FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113990040> ?p ?o ?g. }

• W2113990040 endingPage "2856" @default.
• W2113990040 startingPage "2841" @default.
• W2113990040 abstract "The plant-specific Rop family GTPases are versatile molecular switches in many processes during plant growth, development, and responses to the environment. To understand how Rop achieves its functional versatility in signaling, we performed a genome-wide identification of putative Rop targets using a combination of the yeast two-hybrid method, bioinformatic tools, and a robust functional assay in pollen. In this study, we have identified 11 Arabidopsis genes encoding novel proteins, termed RICs (for Rop-interactive CRIB motif-containing proteins), that contain a CRIB (for Cdc42/Rac-interactive binding) motif required for their specific interaction with GTP-bound Rop1. RICs are divergent and classified into five groups that share little sequence homology outside of the conserved Rop-interactive domain. Overexpression in tobacco pollen tubes of the nine Ric genes that are expressed in Arabidopsis pollen causes distinct phenotypes, implying distinct functions for various RICs. RIC3 (group III) and RIC4 (group V) both cause depolarized growth like Rop1 and display Rop1-enhanced localization to the tip of pollen tubes, suggesting that these RICs may be two distinct targets of Rop1. In contrast, RIC10 (group I) promotes pollen tube elongation but does not affect pollen tube growth polarity and shows Rop1-independent localization to the cytoplasm, suggesting that RIC10 may participate in a Rop1-independent pathway probably controlled by a different Rop. Expression of all other RICs causes various degrees of growth inhibition in pollen tubes. Furthermore, these inhibitory RICs also exhibit distinct patterns of localization in pollen tubes. Our results suggest that various RICs have evolved to interact with Rops differentially and to perform distinct functions in pollen tubes. Reverse transcriptase-mediated polymerase chain reaction analysis showed that six of the nine RICs are expressed in various parts of Arabidopsis plants. On the basis of these observations, we propose that RICs function as Rop GTPase targets that control various Rop-dependent signaling pathways in plants." @default.
• W2113990040 created "2016-06-24" @default.
• W2113990040 creator A5010142228 @default.
• W2113990040 creator A5056484536 @default.
• W2113990040 creator A5079079952 @default.
• W2113990040 creator A5089182062 @default.
• W2113990040 date "2001-12-01" @default.
• W2113990040 modified "2023-09-27" @default.
• W2113990040 title "A Genome-Wide Analysis of Arabidopsis Rop-Interactive CRIB Motif–Containing Proteins That Act as Rop GTPase Targets" @default.
• W2113990040 cites W1494075612 @default.
• W2113990040 cites W1597609173 @default.
• W2113990040 cites W1968049992 @default.
• W2113990040 cites W1988265411 @default.
• W2113990040 cites W1990134601 @default.
• W2113990040 cites W1995774065 @default.
• W2113990040 cites W1995979535 @default.
• W2113990040 cites W2019851613 @default.
• W2113990040 cites W2034266654 @default.
• W2113990040 cites W2036123452 @default.
• W2113990040 cites W2042376897 @default.
• W2113990040 cites W2052140010 @default.
• W2113990040 cites W2063274102 @default.
• W2113990040 cites W2069078351 @default.
• W2113990040 cites W2093396713 @default.
• W2113990040 cites W2111624352 @default.
• W2113990040 cites W2112387650 @default.
• W2113990040 cites W2114489109 @default.
• W2113990040 cites W2122095261 @default.
• W2113990040 cites W2127755033 @default.
• W2113990040 cites W2130608091 @default.
• W2113990040 cites W2133166167 @default.
• W2113990040 cites W2133971749 @default.
• W2113990040 cites W2146967896 @default.
• W2113990040 cites W2151010232 @default.
• W2113990040 cites W2159847655 @default.
• W2113990040 cites W2170279909 @default.
• W2113990040 doi "https://doi.org/10.1105/tpc.010218" @default.
• W2113990040 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/139492" @default.
• W2113990040 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11752391" @default.
• W2113990040 hasPublicationYear "2001" @default.
• W2113990040 type Work @default.
• W2113990040 sameAs 2113990040 @default.
• W2113990040 citedByCount "78" @default.
• W2113990040 countsByYear W21139900402012 @default.
• W2113990040 countsByYear W21139900402013 @default.
• W2113990040 countsByYear W21139900402014 @default.
• W2113990040 countsByYear W21139900402015 @default.
• W2113990040 countsByYear W21139900402016 @default.
• W2113990040 countsByYear W21139900402017 @default.
• W2113990040 countsByYear W21139900402018 @default.
• W2113990040 countsByYear W21139900402019 @default.
• W2113990040 countsByYear W21139900402020 @default.
• W2113990040 countsByYear W21139900402021 @default.
• W2113990040 countsByYear W21139900402022 @default.
• W2113990040 countsByYear W21139900402023 @default.
• W2113990040 crossrefType "journal-article" @default.
• W2113990040 hasAuthorship W2113990040A5010142228 @default.
• W2113990040 hasAuthorship W2113990040A5056484536 @default.
• W2113990040 hasAuthorship W2113990040A5079079952 @default.
• W2113990040 hasAuthorship W2113990040A5089182062 @default.
• W2113990040 hasBestOaLocation W21139900401 @default.
• W2113990040 hasConcept C104317684 @default.
• W2113990040 hasConcept C141231307 @default.
• W2113990040 hasConcept C143065580 @default.
• W2113990040 hasConcept C168197293 @default.
• W2113990040 hasConcept C190062978 @default.
• W2113990040 hasConcept C207332259 @default.
• W2113990040 hasConcept C2779491563 @default.
• W2113990040 hasConcept C2780040266 @default.
• W2113990040 hasConcept C2780618852 @default.
• W2113990040 hasConcept C34069715 @default.
• W2113990040 hasConcept C54355233 @default.
• W2113990040 hasConcept C59822182 @default.
• W2113990040 hasConcept C70721500 @default.
• W2113990040 hasConcept C86803240 @default.
• W2113990040 hasConcept C95444343 @default.
• W2113990040 hasConceptScore W2113990040C104317684 @default.
• W2113990040 hasConceptScore W2113990040C141231307 @default.
• W2113990040 hasConceptScore W2113990040C143065580 @default.
• W2113990040 hasConceptScore W2113990040C168197293 @default.
• W2113990040 hasConceptScore W2113990040C190062978 @default.
• W2113990040 hasConceptScore W2113990040C207332259 @default.
• W2113990040 hasConceptScore W2113990040C2779491563 @default.
• W2113990040 hasConceptScore W2113990040C2780040266 @default.
• W2113990040 hasConceptScore W2113990040C2780618852 @default.
• W2113990040 hasConceptScore W2113990040C34069715 @default.
• W2113990040 hasConceptScore W2113990040C54355233 @default.
• W2113990040 hasConceptScore W2113990040C59822182 @default.
• W2113990040 hasConceptScore W2113990040C70721500 @default.
• W2113990040 hasConceptScore W2113990040C86803240 @default.
• W2113990040 hasConceptScore W2113990040C95444343 @default.
• W2113990040 hasIssue "12" @default.
• W2113990040 hasLocation W21139900401 @default.
• W2113990040 hasLocation W21139900402 @default.
• W2113990040 hasLocation W21139900403 @default.
• W2113990040 hasOpenAccess W2113990040 @default.
• W2113990040 hasPrimaryLocation W21139900401 @default.
• W2113990040 hasRelatedWork W137966601 @default.

• next