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- W2113996001 endingPage "596" @default.
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- W2113996001 abstract "An important mechanism in apoptotic regulation is changes in the subcellular distribution of pro- and anti-apoptotic proteins. Among the proteins that change in their localization and may promote apoptosis are nuclear proteins. Several of these nuclear proteins such as p53, Nur77, histone H1.2, and nucleophosmin were reported to accumulate in the cytosol and/or mitochondria and to promote the mitochondrial apoptotic pathway in response to apoptotic stressors. In this review, we will discuss the functions of these and other nuclear proteins in promoting the mitochondrial apoptotic pathway, the mechanisms that regulate their accumulation in the cytosol and/or mitochondria and the potential role of Bax and Bak in this process. This article is part of a Special Issue entitled Mitochondria: the deadly organelle." @default.
- W2113996001 created "2016-06-24" @default.
- W2113996001 creator A5015590263 @default.
- W2113996001 creator A5082591582 @default.
- W2113996001 creator A5090130012 @default.
- W2113996001 date "2011-04-01" @default.
- W2113996001 modified "2023-10-11" @default.
- W2113996001 title "Nuclear proteins acting on mitochondria" @default.
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