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• W2114004293 endingPage "2036" @default.
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• W2114004293 abstract "<h3>BACKGROUND AND PURPOSE:</h3> Different and specific MR imaging patterns of lesions involving WM are widely defined in neonatal encephalopathy. The aim of this study was to describe a novel MR imaging pattern of damage characterized by the abnormal prominence of DMVs in premature and full-term neonates. <h3>MATERIALS AND METHODS:</h3> Twenty-one (11 premature and 10 full-term) neonates with MR imaging evidence of linear radially oriented fan-shaped lesions in the periventricular WM and without dural venous thrombosis were enrolled in this retrospective study. A total of 37 MR imaging examinations were performed at ages ranging from day 0 to 24 months. <h3>RESULTS:</h3> According to the appearance of linear anomalies on T2-weighted images, we identified 2 main patterns: T2 hypointense lesions without WM cavitations and T2 hypointense lesions associated with linear cysts. The first pattern was found in 17 examinations performed between 0 and 44 days of life; the second pattern was found in another 14 examinations performed between 6 days and 4 months of life. Five examinations performed between 9 and 24 months of life showed a reduction in volume and hyperintense signal intensity of the periventricular WM on T2-weighted and FLAIR images. <h3>CONCLUSIONS:</h3> Subtle linear WM lesions with the same anatomic distribution of DMVs may be evident in premature and full-term neonates without signs of major venous thrombosis, both in the acute and subacute phases. Their appearance and evolution suggest that transient DMV engorgement/thrombosis may be responsible for WM damage that can lead to a PVL-like pattern." @default.
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• W2114004293 date "2011-09-29" @default.
• W2114004293 modified "2023-10-11" @default.
• W2114004293 title "Deep Medullary Vein Involvement in Neonates with Brain Damage: An MR Imaging Study" @default.
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• W2114004293 doi "https://doi.org/10.3174/ajnr.a2687" @default.
• W2114004293 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7964414" @default.
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