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- W2114062442 abstract "Somatically acquired chromosometranslocations are the major mechanismfor gene activation in hematologic ma-lignancies, but they have not been de-scribed previously in the more commonepithelial tumors, such as lung cancers.Furthermore, lung carcinomas often ex-hibit complex karyotypes, and this com-plexity has been assumed to imply a lackof specificity. Indeed, chromosomal de-letions associated with mutations in tu-mor suppressor genes, or gene amplifi-cations of dominant oncogenes, arewell-known genetic abnormalities inthese tumors" @default.
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- W2114062442 date "2000-08-16" @default.
- W2114062442 modified "2023-09-25" @default.
- W2114062442 title "Chromosome 19 Translocation, Overexpression of Notch3, and Human Lung Cancer" @default.
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- W2114062442 doi "https://doi.org/10.1093/jnci/92.16.1355" @default.
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