Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114062685> ?p ?o ?g. }
- W2114062685 endingPage "8" @default.
- W2114062685 startingPage "1" @default.
- W2114062685 abstract "In this work, we examined structural changes of actin filaments interacting with myosin visualized by quick freeze deep-etch replica electron microscopy (EM) by using a new method of image processing/analysis based on mathematical morphology. In order to quantify the degree of structural changes, two characteristic patterns were extracted from the EM images. One is the winding pattern of the filament shape (WP) reflecting flexibility of the filament, and the other is the surface pattern of the filament (SP) reflecting intra-molecular domain-mobility of actin monomers constituting the filament. EM images were processed by morphological filtering followed by box-counting to calculate the fractal dimensions for WP (D(WP)) and SP (D(SP)). The result indicates that D(WP) was larger than D(SP) irrespective of the state of the filament (myosin-free or bound) and that both parameters for myosin-bound filaments were significantly larger than those for myosin-free filaments. Overall, this work provides the first quantitative insight into how conformational disorder of actin monomers is correlated with the myosin-induced increase in flexibility of actin filaments along their length as suggested by earlier studies with different techniques. Our method is yet to be improved in details, but promising as a powerful tool for studying the structural change of protein molecules and their assemblies, which can potentially be applied to a wide range of biological and biomedical images." @default.
- W2114062685 created "2016-06-24" @default.
- W2114062685 creator A5000415993 @default.
- W2114062685 creator A5017391296 @default.
- W2114062685 creator A5026230089 @default.
- W2114062685 creator A5059519917 @default.
- W2114062685 date "2011-10-01" @default.
- W2114062685 modified "2023-09-27" @default.
- W2114062685 title "Fractal dimension analysis and mathematical morphology of structural changes in actin filaments imaged by electron microscopy" @default.
- W2114062685 cites W1966790935 @default.
- W2114062685 cites W1970049715 @default.
- W2114062685 cites W1970800786 @default.
- W2114062685 cites W1972290959 @default.
- W2114062685 cites W1985081051 @default.
- W2114062685 cites W1998463775 @default.
- W2114062685 cites W2002300976 @default.
- W2114062685 cites W2004339398 @default.
- W2114062685 cites W2008815323 @default.
- W2114062685 cites W2012709849 @default.
- W2114062685 cites W2017681545 @default.
- W2114062685 cites W2020230501 @default.
- W2114062685 cites W2021167319 @default.
- W2114062685 cites W2026064166 @default.
- W2114062685 cites W2033061682 @default.
- W2114062685 cites W2037319070 @default.
- W2114062685 cites W2039247149 @default.
- W2114062685 cites W2043664506 @default.
- W2114062685 cites W2050914286 @default.
- W2114062685 cites W2052357815 @default.
- W2114062685 cites W2052781326 @default.
- W2114062685 cites W2053271991 @default.
- W2114062685 cites W2060482091 @default.
- W2114062685 cites W2061662766 @default.
- W2114062685 cites W2077353456 @default.
- W2114062685 cites W2078815478 @default.
- W2114062685 cites W2081201371 @default.
- W2114062685 cites W2083007032 @default.
- W2114062685 cites W2085367586 @default.
- W2114062685 cites W2090568849 @default.
- W2114062685 cites W2098368581 @default.
- W2114062685 cites W2109564101 @default.
- W2114062685 cites W2114371913 @default.
- W2114062685 cites W2130027506 @default.
- W2114062685 cites W2134536686 @default.
- W2114062685 cites W2140040046 @default.
- W2114062685 cites W2152812894 @default.
- W2114062685 cites W2165242943 @default.
- W2114062685 cites W2172152021 @default.
- W2114062685 cites W329272561 @default.
- W2114062685 doi "https://doi.org/10.1016/j.jsb.2011.07.007" @default.
- W2114062685 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21801838" @default.
- W2114062685 hasPublicationYear "2011" @default.
- W2114062685 type Work @default.
- W2114062685 sameAs 2114062685 @default.
- W2114062685 citedByCount "13" @default.
- W2114062685 countsByYear W21140626852012 @default.
- W2114062685 countsByYear W21140626852013 @default.
- W2114062685 countsByYear W21140626852015 @default.
- W2114062685 countsByYear W21140626852016 @default.
- W2114062685 countsByYear W21140626852017 @default.
- W2114062685 countsByYear W21140626852019 @default.
- W2114062685 crossrefType "journal-article" @default.
- W2114062685 hasAuthorship W2114062685A5000415993 @default.
- W2114062685 hasAuthorship W2114062685A5017391296 @default.
- W2114062685 hasAuthorship W2114062685A5026230089 @default.
- W2114062685 hasAuthorship W2114062685A5059519917 @default.
- W2114062685 hasConcept C105795698 @default.
- W2114062685 hasConcept C120665830 @default.
- W2114062685 hasConcept C121332964 @default.
- W2114062685 hasConcept C12554922 @default.
- W2114062685 hasConcept C125705527 @default.
- W2114062685 hasConcept C134306372 @default.
- W2114062685 hasConcept C14228908 @default.
- W2114062685 hasConcept C147080431 @default.
- W2114062685 hasConcept C15954220 @default.
- W2114062685 hasConcept C185592680 @default.
- W2114062685 hasConcept C186060115 @default.
- W2114062685 hasConcept C192562407 @default.
- W2114062685 hasConcept C20702342 @default.
- W2114062685 hasConcept C26546657 @default.
- W2114062685 hasConcept C2780598303 @default.
- W2114062685 hasConcept C33923547 @default.
- W2114062685 hasConcept C40636538 @default.
- W2114062685 hasConcept C55493867 @default.
- W2114062685 hasConcept C6997183 @default.
- W2114062685 hasConcept C8010536 @default.
- W2114062685 hasConcept C8035138 @default.
- W2114062685 hasConcept C86803240 @default.
- W2114062685 hasConcept C93877712 @default.
- W2114062685 hasConceptScore W2114062685C105795698 @default.
- W2114062685 hasConceptScore W2114062685C120665830 @default.
- W2114062685 hasConceptScore W2114062685C121332964 @default.
- W2114062685 hasConceptScore W2114062685C12554922 @default.
- W2114062685 hasConceptScore W2114062685C125705527 @default.
- W2114062685 hasConceptScore W2114062685C134306372 @default.
- W2114062685 hasConceptScore W2114062685C14228908 @default.
- W2114062685 hasConceptScore W2114062685C147080431 @default.
- W2114062685 hasConceptScore W2114062685C15954220 @default.