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• W2114081005 abstract "To determine the efficacy and safety of infliximab in the treatment of refractory posterior uveitis.Noncomparative interventional case series.Five patients with posterior uveitis were treated: 3 had Behçet's syndrome, and 2 had idiopathic posterior uveitis.Patients with sight-threatening uveitis refractory to other immunosuppressive agents were treated with infliximab.Intraocular inflammation, by using binocular indirect ophthalmoscopy score, retinal vasculitis, and visual acuity. Adverse effects of infliximab were documented.Within 2 weeks of the first infusion of infliximab, 4 of 5 patients showed marked improvement in vitreous haze and visual acuity. By the 6-month follow-up, the same four patients had achieved remission of posterior uveitis and had successfully withdrawn all other immunosuppressive therapy. Further infusions of infliximab were required in 3 patients. One patient developed ocular and systemic tuberculosis, which responded to antituberculous treatment.Infliximab is effective in the treatment of sight-threatening refractory posterior uveitis. However, patients should be thoroughly screened for tuberculosis before treatment and followed up closely during and after therapy with infliximab." @default.
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• W2114081005 date "2003-07-01" @default.
• W2114081005 modified "2023-09-27" @default.
• W2114081005 title "Infliximab in the treatment of refractory posterior uveitis" @default.
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• W2114081005 doi "https://doi.org/10.1016/s0161-6420(03)00406-8" @default.
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