FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114090595> ?p ?o ?g. }

• W2114090595 endingPage "850" @default.
• W2114090595 startingPage "844" @default.
• W2114090595 abstract "Abstract Osteoarthritis (OA) is a major degenerative disease affecting millions of individuals. The ability of articular cartilage to self‐repair is limited due to a low tissue turnover rate and the avascular nature of the cartilage, making OA an irreversible disease. In Korea, however, many traditional Korean medical doctors have treated joint disease with a prescription of traditional Korean medicine, BaekJeolYuSin‐tang (BYT). Thus, the chondroprotective effects of BYT and its active component, berberine (Ber) were investigated in an experimental model. Here it is shown that BYT or Ber significantly inhibited the expression of matrix metalloproteinase (MMP)‐3 and a disintegrin and metalloproteinase with thrombospondin motifs‐5 as well as increasing the expression of tissue inhibitors of metalloproteinase‐1, aggrecan and collagen in rabbit articular chondrocytes ( p < 0.05). BYT or Ber significantly inhibited the secretion and activity of MMP‐3 ( p < 0.05). In addition, BYT or Ber significantly inhibited the release of collagen and glycosaminoglycan into the culture media from rabbit articular cartilage explants ( p < 0.05). The data suggest that BYT or Ber has a therapeutic potential for the treatment of cartilage damage in osteoarthritis. Copyright © 2010 John Wiley & Sons, Ltd." @default.
• W2114090595 created "2016-06-24" @default.
• W2114090595 creator A5009961822 @default.
• W2114090595 creator A5046879145 @default.
• W2114090595 creator A5049541329 @default.
• W2114090595 creator A5087688898 @default.
• W2114090595 date "2010-11-19" @default.
• W2114090595 modified "2023-09-27" @default.
• W2114090595 title "Baekjeolyusin-tang and its active component berberine block the release of collagen and proteoglycan from IL-1β-stimulated rabbit cartilage and down-regulate matrix metalloproteinases in rabbit chondrocytes" @default.
• W2114090595 cites W1237294289 @default.
• W2114090595 cites W1538233442 @default.
• W2114090595 cites W1968900840 @default.
• W2114090595 cites W1977040840 @default.
• W2114090595 cites W1994153742 @default.
• W2114090595 cites W2007033032 @default.
• W2114090595 cites W2007622743 @default.
• W2114090595 cites W2012899141 @default.
• W2114090595 cites W2018225482 @default.
• W2114090595 cites W2023714013 @default.
• W2114090595 cites W2050178836 @default.
• W2114090595 cites W2053342448 @default.
• W2114090595 cites W2053628893 @default.
• W2114090595 cites W2068839516 @default.
• W2114090595 cites W2069745732 @default.
• W2114090595 cites W2078884339 @default.
• W2114090595 cites W2120312541 @default.
• W2114090595 cites W2130478732 @default.
• W2114090595 cites W2133032095 @default.
• W2114090595 cites W2133896679 @default.
• W2114090595 cites W2142608022 @default.
• W2114090595 cites W2164082697 @default.
• W2114090595 cites W2166892087 @default.
• W2114090595 doi "https://doi.org/10.1002/ptr.3353" @default.
• W2114090595 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21089182" @default.
• W2114090595 hasPublicationYear "2010" @default.
• W2114090595 type Work @default.
• W2114090595 sameAs 2114090595 @default.
• W2114090595 citedByCount "21" @default.
• W2114090595 countsByYear W21140905952013 @default.
• W2114090595 countsByYear W21140905952014 @default.
• W2114090595 countsByYear W21140905952015 @default.
• W2114090595 countsByYear W21140905952016 @default.
• W2114090595 countsByYear W21140905952017 @default.
• W2114090595 countsByYear W21140905952018 @default.
• W2114090595 countsByYear W21140905952020 @default.
• W2114090595 countsByYear W21140905952021 @default.
• W2114090595 countsByYear W21140905952022 @default.
• W2114090595 countsByYear W21140905952023 @default.
• W2114090595 crossrefType "journal-article" @default.
• W2114090595 hasAuthorship W2114090595A5009961822 @default.
• W2114090595 hasAuthorship W2114090595A5046879145 @default.
• W2114090595 hasAuthorship W2114090595A5049541329 @default.
• W2114090595 hasAuthorship W2114090595A5087688898 @default.
• W2114090595 hasConcept C105702510 @default.
• W2114090595 hasConcept C109523444 @default.
• W2114090595 hasConcept C126322002 @default.
• W2114090595 hasConcept C134018914 @default.
• W2114090595 hasConcept C142724271 @default.
• W2114090595 hasConcept C153074725 @default.
• W2114090595 hasConcept C153911025 @default.
• W2114090595 hasConcept C167814343 @default.
• W2114090595 hasConcept C185592680 @default.
• W2114090595 hasConcept C197534660 @default.
• W2114090595 hasConcept C204787440 @default.
• W2114090595 hasConcept C2776164576 @default.
• W2114090595 hasConcept C2776224515 @default.
• W2114090595 hasConcept C2779335624 @default.
• W2114090595 hasConcept C2780116568 @default.
• W2114090595 hasConcept C2780550940 @default.
• W2114090595 hasConcept C3020332539 @default.
• W2114090595 hasConcept C55493867 @default.
• W2114090595 hasConcept C55728118 @default.
• W2114090595 hasConcept C71924100 @default.
• W2114090595 hasConcept C86803240 @default.
• W2114090595 hasConcept C98274493 @default.
• W2114090595 hasConceptScore W2114090595C105702510 @default.
• W2114090595 hasConceptScore W2114090595C109523444 @default.
• W2114090595 hasConceptScore W2114090595C126322002 @default.
• W2114090595 hasConceptScore W2114090595C134018914 @default.
• W2114090595 hasConceptScore W2114090595C142724271 @default.
• W2114090595 hasConceptScore W2114090595C153074725 @default.
• W2114090595 hasConceptScore W2114090595C153911025 @default.
• W2114090595 hasConceptScore W2114090595C167814343 @default.
• W2114090595 hasConceptScore W2114090595C185592680 @default.
• W2114090595 hasConceptScore W2114090595C197534660 @default.
• W2114090595 hasConceptScore W2114090595C204787440 @default.
• W2114090595 hasConceptScore W2114090595C2776164576 @default.
• W2114090595 hasConceptScore W2114090595C2776224515 @default.
• W2114090595 hasConceptScore W2114090595C2779335624 @default.
• W2114090595 hasConceptScore W2114090595C2780116568 @default.
• W2114090595 hasConceptScore W2114090595C2780550940 @default.
• W2114090595 hasConceptScore W2114090595C3020332539 @default.
• W2114090595 hasConceptScore W2114090595C55493867 @default.
• W2114090595 hasConceptScore W2114090595C55728118 @default.
• W2114090595 hasConceptScore W2114090595C71924100 @default.
• W2114090595 hasConceptScore W2114090595C86803240 @default.
• W2114090595 hasConceptScore W2114090595C98274493 @default.
• W2114090595 hasIssue "6" @default.

• next