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• W2114098158 abstract "A fluorescent pH probe, N,N'-bi( l-phenylalanine amine)-perylene-3,4;9,10-dicarboxylic diimide (PDCDA) was synthesized and used for pH sensing in living cells. A significant fluorescence intensity change was observed over a pH range from 7.0 to 4.0. Electrostatic potential maps (MEP) suggested that the electronic repulsion between PDCDAs was increased by the high negative electrostatic potential which resulted in a high water solubility of PDCDA. PDCDA was successfully applied as a high-performance fluorochrome for living HeLa cell imaging. The results demonstrate that the probe PDCDA is a good candidate for monitoring pH fluctuations in living cells with good water solubility, low cytotoxicity, high fluorescence quantum yield and photostability." @default.
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• W2114098158 date "2015-05-26" @default.
• W2114098158 modified "2023-10-16" @default.
• W2114098158 title "A water-soluble fluorescent pH probe based on perylene dyes and its application to cell imaging" @default.
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• W2114098158 doi "https://doi.org/10.1002/bio.2930" @default.
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