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- W2114150857 abstract "To characterize the association of low HbA(1c) values (<4.0%) with liver enzymes and steatosis.Cross-sectional study of 12,533 participants without diabetes aged <20 years in the Third National Health and Nutrition Examination Survey (1988-1994). Logistic regression models were adjusted for demographic, lifestyle, and health status variables.HbA(1c) values ranged from 3.2 to 15.7%, and 84 participants had HbA(1c) <4.0% in the population (mean age 44, 52% female, 15% black or Hispanic). We observed J-shaped associations between HbA(1c) and liver enzymes and hepatic steatosis. In adjusted models, HbA(1c) <4.0% was strongly associated with elevated alanine aminotransferase (OR 3.62 [95% CI 1.09-12.02]) and aspartate aminotransferase (6.80 [2.99-15.43]).Low HbA(1c) values were associated with liver enzymes and steatosis in the U.S. population. Liver disease may partially explain the association of HbA(1c) with mortality and other long-term outcomes." @default.
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- W2114150857 date "2011-11-14" @default.
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- W2114150857 title "Low Glycated Hemoglobin and Liver Disease in the U.S. Population" @default.
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- W2114150857 doi "https://doi.org/10.2337/dc11-0944" @default.
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