FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114253485> ?p ?o ?g. }

• W2114253485 endingPage "17344" @default.
• W2114253485 startingPage "17344" @default.
• W2114253485 abstract "Introduction Intensive care mortality of HIV-positive patients has progressively decreased. However, critically ill HIV-positive patients with sepsis present a worse prognosis. To better understand this condition, we propose a study comparing clinical, etiological and inflammatory data, and the hospital course of HIV-positive and HIV-negative patients with severe sepsis or septic shock. Methods A prospective observational study enrolling patients with severe sepsis or septic shock associated or not with HIV infection, and admitted to intensive care unit (ICU). Clinical, microbiological and inflammatory parameters were assessed, including C-reactive protein (CRP), procalcitonin (PCT), interleukin-6, interleukin-10 and TNF-α. Outcome measures were in-hospital and six-month mortality. Results The study included 58 patients with severe sepsis/septic shock admitted to ICU, 36 HIV-positive and 22 HIV-negative. All HIV-positive patients met the criteria for AIDS (CDC/2008). The main foci of infection in HIV-positive patients were pulmonary and abdominal (p=0.001). Fungi and mycobacteria were identified in 44.4% and 16.7% of HIV-positive patients, respectively. In contrast, the main etiologies for sepsis in HIV-negative patients were Gram-negative bacilli (36.4%) and Gram-positive cocci (36.4%) (p=0.001). CRP and PCT admission concentrations were lower in HIV-positive patients (130 vs. 168 mg/dL p=0.005, and 1.19 vs. 4.06 ng/mL p=0.04, respectively), with a progressive decrease in surviving patients. Initial IL-10 concentrations were higher in HIV-positive patients (4.4 pg/mL vs. 1.0 pg/mL, p=0.005), with moderate accuracy for predicting death (area under receiver-operating characteristic curve =0.74). In-hospital and six-month mortality were higher in HIV-positive patients (55.6 vs. 27.3% p=0.03, and 58.3 vs. 27.3% p=0.02, respectively). Conclusions The course of sepsis was more severe in HIV-positive patients, with distinct clinical, etiological and inflammatory characteristics." @default.
• W2114253485 created "2016-06-24" @default.
• W2114253485 creator A5049115631 @default.
• W2114253485 creator A5072344112 @default.
• W2114253485 date "2013-01-01" @default.
• W2114253485 modified "2023-09-24" @default.
• W2114253485 title "Sepsis in AIDS patients: clinical, etiological and inflammatory characteristics" @default.
• W2114253485 cites W1493216 @default.
• W2114253485 cites W1550361939 @default.
• W2114253485 cites W1967216989 @default.
• W2114253485 cites W1968201338 @default.
• W2114253485 cites W1972350167 @default.
• W2114253485 cites W1972922117 @default.
• W2114253485 cites W1987784268 @default.
• W2114253485 cites W1988405217 @default.
• W2114253485 cites W1992859813 @default.
• W2114253485 cites W2000536195 @default.
• W2114253485 cites W2001280008 @default.
• W2114253485 cites W2007810526 @default.
• W2114253485 cites W2016095124 @default.
• W2114253485 cites W2018760046 @default.
• W2114253485 cites W2023722505 @default.
• W2114253485 cites W2028763115 @default.
• W2114253485 cites W2037719985 @default.
• W2114253485 cites W2049927822 @default.
• W2114253485 cites W2051613953 @default.
• W2114253485 cites W2058830508 @default.
• W2114253485 cites W2059930206 @default.
• W2114253485 cites W2070074382 @default.
• W2114253485 cites W2078703682 @default.
• W2114253485 cites W2088331635 @default.
• W2114253485 cites W2091198122 @default.
• W2114253485 cites W2096356210 @default.
• W2114253485 cites W2111117400 @default.
• W2114253485 cites W2113859378 @default.
• W2114253485 cites W2121943809 @default.
• W2114253485 cites W2128545633 @default.
• W2114253485 cites W2129736254 @default.
• W2114253485 cites W2129875748 @default.
• W2114253485 cites W2131628858 @default.
• W2114253485 cites W2132050458 @default.
• W2114253485 cites W2134923759 @default.
• W2114253485 cites W2142124064 @default.
• W2114253485 cites W2145530209 @default.
• W2114253485 cites W2150948831 @default.
• W2114253485 cites W2151556259 @default.
• W2114253485 cites W2152357679 @default.
• W2114253485 cites W2152955526 @default.
• W2114253485 cites W2154077281 @default.
• W2114253485 cites W2154740531 @default.
• W2114253485 cites W2161041003 @default.
• W2114253485 cites W2166162509 @default.
• W2114253485 cites W2335322575 @default.
• W2114253485 cites W4293242440 @default.
• W2114253485 doi "https://doi.org/10.7448/ias.16.1.17344" @default.
• W2114253485 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3564973" @default.
• W2114253485 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23374857" @default.
• W2114253485 hasPublicationYear "2013" @default.
• W2114253485 type Work @default.
• W2114253485 sameAs 2114253485 @default.
• W2114253485 citedByCount "34" @default.
• W2114253485 countsByYear W21142534852013 @default.
• W2114253485 countsByYear W21142534852014 @default.
• W2114253485 countsByYear W21142534852015 @default.
• W2114253485 countsByYear W21142534852016 @default.
• W2114253485 countsByYear W21142534852017 @default.
• W2114253485 countsByYear W21142534852018 @default.
• W2114253485 countsByYear W21142534852019 @default.
• W2114253485 countsByYear W21142534852020 @default.
• W2114253485 countsByYear W21142534852021 @default.
• W2114253485 countsByYear W21142534852022 @default.
• W2114253485 crossrefType "journal-article" @default.
• W2114253485 hasAuthorship W2114253485A5049115631 @default.
• W2114253485 hasAuthorship W2114253485A5072344112 @default.
• W2114253485 hasBestOaLocation W21142534852 @default.
• W2114253485 hasConcept C10936531 @default.
• W2114253485 hasConcept C126322002 @default.
• W2114253485 hasConcept C137627325 @default.
• W2114253485 hasConcept C188816634 @default.
• W2114253485 hasConcept C203014093 @default.
• W2114253485 hasConcept C2776376669 @default.
• W2114253485 hasConcept C2777628635 @default.
• W2114253485 hasConcept C2778384902 @default.
• W2114253485 hasConcept C71924100 @default.
• W2114253485 hasConcept C90924648 @default.
• W2114253485 hasConceptScore W2114253485C10936531 @default.
• W2114253485 hasConceptScore W2114253485C126322002 @default.
• W2114253485 hasConceptScore W2114253485C137627325 @default.
• W2114253485 hasConceptScore W2114253485C188816634 @default.
• W2114253485 hasConceptScore W2114253485C203014093 @default.
• W2114253485 hasConceptScore W2114253485C2776376669 @default.
• W2114253485 hasConceptScore W2114253485C2777628635 @default.
• W2114253485 hasConceptScore W2114253485C2778384902 @default.
• W2114253485 hasConceptScore W2114253485C71924100 @default.
• W2114253485 hasConceptScore W2114253485C90924648 @default.
• W2114253485 hasIssue "1" @default.
• W2114253485 hasLocation W21142534851 @default.
• W2114253485 hasLocation W21142534852 @default.

• next