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- W2114302015 abstract "In this manuscript we summarize the role of chronic stress as a potential trigger factor for Parkinson9s disease. Underlying mechanisms and stress-induced changes to the neuronal networks have been highlighted. Examples of stress induced reversible symptoms that resemble parkinsonism in humans and in animal models raise the question whether emotional stress can cause striatal degeneration in susceptible patients. A Pubmed literature review searching for the terms ‘Stress’, ‘Distress and Parkinson9s disease’, 9Emotional Distress and Parkinson9s disease’, ‘Stress and Parkinson9s disease’, ‘Prodromal Parkinson9s disease’, ‘Non motor symptoms and Parkinson9s disease’, ‘Paradoxical kinesia’, ‘Psychogenic parkinsonism’, ‘Functional somatic syndromes’, ‘Chronic fatigue syndrome’, ‘Irritable bowel syndrome’, ‘Fibromyalgia’, ‘Dopamine and fibromyalgia’, ‘Dopamine and chronic fatigue syndrome’ and ‘Dopamine and irritable bowel syndrome’ was carried out until April 2013. Articles were also identified through searches of the authors’ own files. Only papers published in English were reviewed. The final reference list was generated on the basis of originality and relevance to the broad scope of this viewpoint." @default.
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- W2114302015 date "2013-11-20" @default.
- W2114302015 modified "2023-10-18" @default.
- W2114302015 title "Can stress trigger Parkinson's disease?" @default.
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- W2114302015 doi "https://doi.org/10.1136/jnnp-2013-305911" @default.
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