FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114359463> ?p ?o ?g. }

• W2114359463 endingPage "110" @default.
• W2114359463 startingPage "103" @default.
• W2114359463 abstract "The differentiation of human keratinocytes in most culture systems is incomplete; e.g., lamellar bodies, the characteristic lipid-delivery organelles of epidermis, are not present. Moreover, their lipid profile does not reflect the distinctive composition found in cornifying epidermis. In contrast, keratinocytes that grow at an air-medium interface exhibit more complete differentiation. In this study, we compared the elaboration of lamellar bodies, the lipid content, and the lipid metabolism of human keratinocytes, cultured both under standard immersed conditions and after lifting to an air-medium interface. Whereas submerged cultures neither elaborated lamellar bodies nor displayed a lipid distribution characteristic of cornifying epidermis, lifted cultures displayed advanced cornification, elaborated lamellar bodies which were deposited in intercellular domains, and a lipid profile more typical of cornifying epidermis. Moreover, lipid biosynthesis was 5–10-fold more active in lifted than in immersed cultures, and was not inhibited by exogenous lipoproteins. These findings are consistent with recent studies that demonstrate both high rates of lipogenesis in differentiating layers of the epidermis as well as autonomy of lipogenesis from the influence of circulating lipoproteins. Thus, the lipid content and metabolism of human keratinocyte cultures, grown at an air-medium interface, demonstrate features that simulate the epidermis." @default.
• W2114359463 created "2016-06-24" @default.
• W2114359463 creator A5008415248 @default.
• W2114359463 creator A5048735838 @default.
• W2114359463 creator A5050608918 @default.
• W2114359463 creator A5066400475 @default.
• W2114359463 creator A5083628557 @default.
• W2114359463 date "1988-07-01" @default.
• W2114359463 modified "2023-10-18" @default.
• W2114359463 title "Lipid content and metabolism of human keratinocyte cultures grown at the air-medium interface" @default.
• W2114359463 cites W1612390895 @default.
• W2114359463 cites W1949202479 @default.
• W2114359463 cites W1964539744 @default.
• W2114359463 cites W1967749441 @default.
• W2114359463 cites W1974861398 @default.
• W2114359463 cites W1975921658 @default.
• W2114359463 cites W1975986537 @default.
• W2114359463 cites W1977779461 @default.
• W2114359463 cites W1983851236 @default.
• W2114359463 cites W1985091308 @default.
• W2114359463 cites W1986757006 @default.
• W2114359463 cites W1990545618 @default.
• W2114359463 cites W1995023052 @default.
• W2114359463 cites W2001062031 @default.
• W2114359463 cites W2006170660 @default.
• W2114359463 cites W2017695342 @default.
• W2114359463 cites W2027482987 @default.
• W2114359463 cites W2031958246 @default.
• W2114359463 cites W2038085058 @default.
• W2114359463 cites W2049043712 @default.
• W2114359463 cites W2052095326 @default.
• W2114359463 cites W2071809465 @default.
• W2114359463 cites W2102742421 @default.
• W2114359463 cites W2128280943 @default.
• W2114359463 cites W2137156887 @default.
• W2114359463 cites W2148635708 @default.
• W2114359463 cites W2153695113 @default.
• W2114359463 cites W2169484065 @default.
• W2114359463 cites W2286048934 @default.
• W2114359463 cites W2303771534 @default.
• W2114359463 doi "https://doi.org/10.1002/jcp.1041360113" @default.
• W2114359463 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2456290" @default.
• W2114359463 hasPublicationYear "1988" @default.
• W2114359463 type Work @default.
• W2114359463 sameAs 2114359463 @default.
• W2114359463 citedByCount "51" @default.
• W2114359463 countsByYear W21143594632013 @default.
• W2114359463 countsByYear W21143594632014 @default.
• W2114359463 countsByYear W21143594632017 @default.
• W2114359463 countsByYear W21143594632019 @default.
• W2114359463 countsByYear W21143594632022 @default.
• W2114359463 countsByYear W21143594632023 @default.
• W2114359463 crossrefType "journal-article" @default.
• W2114359463 hasAuthorship W2114359463A5008415248 @default.
• W2114359463 hasAuthorship W2114359463A5048735838 @default.
• W2114359463 hasAuthorship W2114359463A5050608918 @default.
• W2114359463 hasAuthorship W2114359463A5066400475 @default.
• W2114359463 hasAuthorship W2114359463A5083628557 @default.
• W2114359463 hasConcept C105702510 @default.
• W2114359463 hasConcept C12554922 @default.
• W2114359463 hasConcept C141359234 @default.
• W2114359463 hasConcept C145156650 @default.
• W2114359463 hasConcept C168240541 @default.
• W2114359463 hasConcept C185592680 @default.
• W2114359463 hasConcept C202751555 @default.
• W2114359463 hasConcept C25095133 @default.
• W2114359463 hasConcept C2776458125 @default.
• W2114359463 hasConcept C2777074287 @default.
• W2114359463 hasConcept C4733338 @default.
• W2114359463 hasConcept C55493867 @default.
• W2114359463 hasConcept C58226133 @default.
• W2114359463 hasConcept C77851909 @default.
• W2114359463 hasConcept C8010536 @default.
• W2114359463 hasConcept C86803240 @default.
• W2114359463 hasConcept C95444343 @default.
• W2114359463 hasConceptScore W2114359463C105702510 @default.
• W2114359463 hasConceptScore W2114359463C12554922 @default.
• W2114359463 hasConceptScore W2114359463C141359234 @default.
• W2114359463 hasConceptScore W2114359463C145156650 @default.
• W2114359463 hasConceptScore W2114359463C168240541 @default.
• W2114359463 hasConceptScore W2114359463C185592680 @default.
• W2114359463 hasConceptScore W2114359463C202751555 @default.
• W2114359463 hasConceptScore W2114359463C25095133 @default.
• W2114359463 hasConceptScore W2114359463C2776458125 @default.
• W2114359463 hasConceptScore W2114359463C2777074287 @default.
• W2114359463 hasConceptScore W2114359463C4733338 @default.
• W2114359463 hasConceptScore W2114359463C55493867 @default.
• W2114359463 hasConceptScore W2114359463C58226133 @default.
• W2114359463 hasConceptScore W2114359463C77851909 @default.
• W2114359463 hasConceptScore W2114359463C8010536 @default.
• W2114359463 hasConceptScore W2114359463C86803240 @default.
• W2114359463 hasConceptScore W2114359463C95444343 @default.
• W2114359463 hasIssue "1" @default.
• W2114359463 hasLocation W21143594631 @default.
• W2114359463 hasLocation W21143594632 @default.
• W2114359463 hasOpenAccess W2114359463 @default.
• W2114359463 hasPrimaryLocation W21143594631 @default.
• W2114359463 hasRelatedWork W1982801741 @default.

• next