FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114369438> ?p ?o ?g. }

• W2114369438 endingPage "211" @default.
• W2114369438 startingPage "201" @default.
• W2114369438 abstract "There are few data on the role of lipid lowering in the primary prevention of coronary heart disease (CHD) in diabetic patients. This paper describes the design of a collaborative clinical trial between Diabetes UK, the NHS Research and Development Directorate and Pfizer UK, that addresses this question.The Collaborative AtoRvastatin Diabetes Study (CARDS) is a multicentre, randomized, placebo-controlled, double-blind clinical trial of primary prevention of cardiovascular disease in patients with Type 2 diabetes. The primary objective is to investigate whether treatment with the hydroxymethylglutaryl coenzyme A reductase inhibitor, atorvastatin, reduces the incidence of major cardiovascular events. At entry patients have at least one other risk factor for CHD in addition to diabetes, namely current smoking, hypertension, retinopathy, or micro- or macroalbuminuria. At randomization patients have been selected for a serum low-density lipoprotein (LDL) cholesterol concentration < or = 4.14 mmol/l (160 mg/dl) and triglycerides < or = 6.78 mmol/l (600 mg/dl). Randomization was completed in June 2001. Patients will be followed until 304 primary endpoints have accrued (expected date early 2005). The trial includes 2838 men and women aged 40-75 years. This report describes the design and administration of the study and reviews the evidence to date of the effectiveness of lipid-lowering therapy in Type 2 diabetes.The case for lipid-lowering therapy for the primary prevention of CHD in diabetes has not been demonstrated. CARDS will provide essential information on the extent of any benefits and adverse effects of lipid-lowering therapy in diabetic patients without prior CHD." @default.
• W2114369438 created "2016-06-24" @default.
• W2114369438 creator A5005414020 @default.
• W2114369438 creator A5025348013 @default.
• W2114369438 creator A5025686340 @default.
• W2114369438 creator A5037881015 @default.
• W2114369438 creator A5060579337 @default.
• W2114369438 creator A5064649684 @default.
• W2114369438 creator A5067742368 @default.
• W2114369438 creator A5083684284 @default.
• W2114369438 creator A5088991644 @default.
• W2114369438 creator A5089503693 @default.
• W2114369438 date "2002-03-01" @default.
• W2114369438 modified "2023-09-26" @default.
• W2114369438 title "Design of the Collaborative AtoRvastatin Diabetes Study (CARDS) in patients with Type 2 diabetes" @default.
• W2114369438 cites W1970039102 @default.
• W2114369438 cites W1987280351 @default.
• W2114369438 cites W2001979704 @default.
• W2114369438 cites W2005761359 @default.
• W2114369438 cites W2013837699 @default.
• W2114369438 cites W2014759828 @default.
• W2114369438 cites W2018715171 @default.
• W2114369438 cites W2024872277 @default.
• W2114369438 cites W2029368789 @default.
• W2114369438 cites W2035440468 @default.
• W2114369438 cites W2051674344 @default.
• W2114369438 cites W2053365438 @default.
• W2114369438 cites W2059537042 @default.
• W2114369438 cites W2080585365 @default.
• W2114369438 cites W2101813912 @default.
• W2114369438 cites W2106756736 @default.
• W2114369438 cites W2115728877 @default.
• W2114369438 cites W2116404316 @default.
• W2114369438 cites W2123420731 @default.
• W2114369438 cites W2128300830 @default.
• W2114369438 cites W2129750583 @default.
• W2114369438 cites W2146662886 @default.
• W2114369438 cites W2155598961 @default.
• W2114369438 cites W2161261413 @default.
• W2114369438 cites W2328529137 @default.
• W2114369438 cites W2752336761 @default.
• W2114369438 doi "https://doi.org/10.1046/j.1464-5491.2002.00643.x" @default.
• W2114369438 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11918622" @default.
• W2114369438 hasPublicationYear "2002" @default.
• W2114369438 type Work @default.
• W2114369438 sameAs 2114369438 @default.
• W2114369438 citedByCount "92" @default.
• W2114369438 countsByYear W21143694382012 @default.
• W2114369438 countsByYear W21143694382013 @default.
• W2114369438 countsByYear W21143694382014 @default.
• W2114369438 countsByYear W21143694382015 @default.
• W2114369438 countsByYear W21143694382016 @default.
• W2114369438 countsByYear W21143694382017 @default.
• W2114369438 countsByYear W21143694382018 @default.
• W2114369438 countsByYear W21143694382020 @default.
• W2114369438 countsByYear W21143694382022 @default.
• W2114369438 countsByYear W21143694382023 @default.
• W2114369438 crossrefType "journal-article" @default.
• W2114369438 hasAuthorship W2114369438A5005414020 @default.
• W2114369438 hasAuthorship W2114369438A5025348013 @default.
• W2114369438 hasAuthorship W2114369438A5025686340 @default.
• W2114369438 hasAuthorship W2114369438A5037881015 @default.
• W2114369438 hasAuthorship W2114369438A5060579337 @default.
• W2114369438 hasAuthorship W2114369438A5064649684 @default.
• W2114369438 hasAuthorship W2114369438A5067742368 @default.
• W2114369438 hasAuthorship W2114369438A5083684284 @default.
• W2114369438 hasAuthorship W2114369438A5088991644 @default.
• W2114369438 hasAuthorship W2114369438A5089503693 @default.
• W2114369438 hasConcept C126322002 @default.
• W2114369438 hasConcept C134018914 @default.
• W2114369438 hasConcept C142724271 @default.
• W2114369438 hasConcept C168563851 @default.
• W2114369438 hasConcept C203092338 @default.
• W2114369438 hasConcept C204787440 @default.
• W2114369438 hasConcept C27081682 @default.
• W2114369438 hasConcept C2777180221 @default.
• W2114369438 hasConcept C2777482532 @default.
• W2114369438 hasConcept C535046627 @default.
• W2114369438 hasConcept C555293320 @default.
• W2114369438 hasConcept C71924100 @default.
• W2114369438 hasConceptScore W2114369438C126322002 @default.
• W2114369438 hasConceptScore W2114369438C134018914 @default.
• W2114369438 hasConceptScore W2114369438C142724271 @default.
• W2114369438 hasConceptScore W2114369438C168563851 @default.
• W2114369438 hasConceptScore W2114369438C203092338 @default.
• W2114369438 hasConceptScore W2114369438C204787440 @default.
• W2114369438 hasConceptScore W2114369438C27081682 @default.
• W2114369438 hasConceptScore W2114369438C2777180221 @default.
• W2114369438 hasConceptScore W2114369438C2777482532 @default.
• W2114369438 hasConceptScore W2114369438C535046627 @default.
• W2114369438 hasConceptScore W2114369438C555293320 @default.
• W2114369438 hasConceptScore W2114369438C71924100 @default.
• W2114369438 hasIssue "3" @default.
• W2114369438 hasLocation W21143694381 @default.
• W2114369438 hasLocation W21143694382 @default.
• W2114369438 hasOpenAccess W2114369438 @default.
• W2114369438 hasPrimaryLocation W21143694381 @default.
• W2114369438 hasRelatedWork W2003150205 @default.

• next