Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114379621> ?p ?o ?g. }
- W2114379621 endingPage "8610" @default.
- W2114379621 startingPage "8600" @default.
- W2114379621 abstract "In the nucleolus the U3 snoRNA is recruited to the 80S pre-rRNA processing complex in the dense fibrillar component (DFC). The U3 snoRNA is found throughout the nucleolus and has been proposed to move with the preribosomes to the granular component (GC). In contrast, the localization of other RNAs, such as the U8 snoRNA, is restricted to the DFC. Here we show that the incorporation of the U3 snoRNA into the 80S processing complex is not dependent on pre-rRNA base pairing sequences but requires the B/C motif, a U3-specific protein-binding element. We also show that the binding of Mpp10 to the 80S U3 complex is dependent on sequences within the U3 snoRNA that base pair with the pre-rRNA adjacent to the initial cleavage site. Furthermore, mutations that inhibit 80S complex formation and/or the association of Mpp10 result in retention of the U3 snoRNA in the DFC. From this we propose that the GC localization of the U3 snoRNA is a direct result of its active involvement in the initial steps of ribosome biogenesis." @default.
- W2114379621 created "2016-06-24" @default.
- W2114379621 creator A5023962178 @default.
- W2114379621 creator A5024316359 @default.
- W2114379621 creator A5053030519 @default.
- W2114379621 creator A5056082573 @default.
- W2114379621 creator A5077613316 @default.
- W2114379621 creator A5081889079 @default.
- W2114379621 date "2004-10-01" @default.
- W2114379621 modified "2023-09-27" @default.
- W2114379621 title "Role of Pre-rRNA Base Pairing and 80S Complex Formation in Subnucleolar Localization of the U3 snoRNP" @default.
- W2114379621 cites W109701900 @default.
- W2114379621 cites W1494838952 @default.
- W2114379621 cites W1506119659 @default.
- W2114379621 cites W1565721167 @default.
- W2114379621 cites W1869558150 @default.
- W2114379621 cites W1970148613 @default.
- W2114379621 cites W1977944225 @default.
- W2114379621 cites W1978458718 @default.
- W2114379621 cites W1989221817 @default.
- W2114379621 cites W1994566492 @default.
- W2114379621 cites W1997874688 @default.
- W2114379621 cites W1998905553 @default.
- W2114379621 cites W2002829809 @default.
- W2114379621 cites W2005042567 @default.
- W2114379621 cites W2008025013 @default.
- W2114379621 cites W2013303176 @default.
- W2114379621 cites W2023905948 @default.
- W2114379621 cites W2024799598 @default.
- W2114379621 cites W2044240925 @default.
- W2114379621 cites W2046559761 @default.
- W2114379621 cites W2065923747 @default.
- W2114379621 cites W2068321397 @default.
- W2114379621 cites W2080459885 @default.
- W2114379621 cites W2081133503 @default.
- W2114379621 cites W2096277488 @default.
- W2114379621 cites W2100400436 @default.
- W2114379621 cites W2108566341 @default.
- W2114379621 cites W2113407635 @default.
- W2114379621 cites W2113711350 @default.
- W2114379621 cites W2116360991 @default.
- W2114379621 cites W2120382578 @default.
- W2114379621 cites W2130848029 @default.
- W2114379621 cites W2132623938 @default.
- W2114379621 cites W2134725862 @default.
- W2114379621 cites W2135107149 @default.
- W2114379621 cites W2140748458 @default.
- W2114379621 cites W2141975228 @default.
- W2114379621 cites W2151443034 @default.
- W2114379621 cites W2152374345 @default.
- W2114379621 cites W2154658130 @default.
- W2114379621 cites W2156671325 @default.
- W2114379621 cites W2157713791 @default.
- W2114379621 cites W2159195583 @default.
- W2114379621 cites W2160102239 @default.
- W2114379621 cites W2161794927 @default.
- W2114379621 cites W2170742997 @default.
- W2114379621 cites W2170808152 @default.
- W2114379621 cites W2171816678 @default.
- W2114379621 cites W2199441825 @default.
- W2114379621 doi "https://doi.org/10.1128/mcb.24.19.8600-8610.2004" @default.
- W2114379621 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/516741" @default.
- W2114379621 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15367679" @default.
- W2114379621 hasPublicationYear "2004" @default.
- W2114379621 type Work @default.
- W2114379621 sameAs 2114379621 @default.
- W2114379621 citedByCount "42" @default.
- W2114379621 countsByYear W21143796212012 @default.
- W2114379621 countsByYear W21143796212013 @default.
- W2114379621 countsByYear W21143796212015 @default.
- W2114379621 countsByYear W21143796212016 @default.
- W2114379621 countsByYear W21143796212017 @default.
- W2114379621 countsByYear W21143796212019 @default.
- W2114379621 countsByYear W21143796212020 @default.
- W2114379621 countsByYear W21143796212023 @default.
- W2114379621 crossrefType "journal-article" @default.
- W2114379621 hasAuthorship W2114379621A5023962178 @default.
- W2114379621 hasAuthorship W2114379621A5024316359 @default.
- W2114379621 hasAuthorship W2114379621A5053030519 @default.
- W2114379621 hasAuthorship W2114379621A5056082573 @default.
- W2114379621 hasAuthorship W2114379621A5077613316 @default.
- W2114379621 hasAuthorship W2114379621A5081889079 @default.
- W2114379621 hasBestOaLocation W21143796212 @default.
- W2114379621 hasConcept C104317684 @default.
- W2114379621 hasConcept C131934819 @default.
- W2114379621 hasConcept C151730666 @default.
- W2114379621 hasConcept C175156509 @default.
- W2114379621 hasConcept C179255354 @default.
- W2114379621 hasConcept C183873130 @default.
- W2114379621 hasConcept C185581394 @default.
- W2114379621 hasConcept C190062978 @default.
- W2114379621 hasConcept C2779419633 @default.
- W2114379621 hasConcept C43369102 @default.
- W2114379621 hasConcept C54355233 @default.
- W2114379621 hasConcept C552990157 @default.
- W2114379621 hasConcept C62203573 @default.
- W2114379621 hasConcept C67705224 @default.
- W2114379621 hasConcept C67905577 @default.