Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114410111> ?p ?o ?g. }
- W2114410111 endingPage "3288" @default.
- W2114410111 startingPage "3281" @default.
- W2114410111 abstract "Wsc1 is a member of a family of highly O-glycosylated cell surface proteins that reside in the plasma membrane of Saccharomyces cerevisiae and function as sensors of cell wall stress. These proteins activate the cell wall integrity signalling pathway by stimulating the small G-protein Rho1, protein kinase C (Pkc1) and a MAP kinase cascade. The cytoplasmic domains of Wsc1 family members interact with the Rom2 guanine nucleotide exchange factor to stimulate GTP-binding of Rho1. Here, a mutational analysis of the cytoplasmic domain of Wsc1 is presented. The data identify two regions of the Wsc1 cytoplasmic tail that are conserved with other family members as important for Rom2 interaction. These regions are separated by an inhibitory region, which includes a cluster of seryl residues that appear to be phosphorylated. Mutational analysis of these residues supports a model in which Wsc1 interaction with Rom2 is negatively regulated by phosphorylation." @default.
- W2114410111 created "2016-06-24" @default.
- W2114410111 creator A5000796046 @default.
- W2114410111 creator A5004022049 @default.
- W2114410111 creator A5056383381 @default.
- W2114410111 date "2004-10-01" @default.
- W2114410111 modified "2023-09-27" @default.
- W2114410111 title "Mutational analysis of the cytoplasmic domain of the Wsc1 cell wall stress sensor" @default.
- W2114410111 cites W1485925377 @default.
- W2114410111 cites W1499601028 @default.
- W2114410111 cites W1526043578 @default.
- W2114410111 cites W1588192538 @default.
- W2114410111 cites W1798150371 @default.
- W2114410111 cites W1864334043 @default.
- W2114410111 cites W1889502940 @default.
- W2114410111 cites W1938343654 @default.
- W2114410111 cites W1961049630 @default.
- W2114410111 cites W1973782344 @default.
- W2114410111 cites W1993191556 @default.
- W2114410111 cites W2002960804 @default.
- W2114410111 cites W2017619665 @default.
- W2114410111 cites W2033133245 @default.
- W2114410111 cites W2034092404 @default.
- W2114410111 cites W2039038110 @default.
- W2114410111 cites W2040518083 @default.
- W2114410111 cites W2040838736 @default.
- W2114410111 cites W2060913542 @default.
- W2114410111 cites W2065220166 @default.
- W2114410111 cites W2068432705 @default.
- W2114410111 cites W2071468845 @default.
- W2114410111 cites W2080229333 @default.
- W2114410111 cites W2090306001 @default.
- W2114410111 cites W2099661865 @default.
- W2114410111 cites W2102824246 @default.
- W2114410111 cites W2123150152 @default.
- W2114410111 cites W2124941588 @default.
- W2114410111 cites W2125672511 @default.
- W2114410111 cites W2130316063 @default.
- W2114410111 cites W2136656652 @default.
- W2114410111 cites W2137127271 @default.
- W2114410111 cites W2142030911 @default.
- W2114410111 cites W2142161768 @default.
- W2114410111 cites W2143924086 @default.
- W2114410111 cites W2151702365 @default.
- W2114410111 cites W2152568223 @default.
- W2114410111 cites W2154035538 @default.
- W2114410111 cites W2169333620 @default.
- W2114410111 doi "https://doi.org/10.1099/mic.0.27264-0" @default.
- W2114410111 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15470108" @default.
- W2114410111 hasPublicationYear "2004" @default.
- W2114410111 type Work @default.
- W2114410111 sameAs 2114410111 @default.
- W2114410111 citedByCount "30" @default.
- W2114410111 countsByYear W21144101112013 @default.
- W2114410111 countsByYear W21144101112014 @default.
- W2114410111 countsByYear W21144101112015 @default.
- W2114410111 countsByYear W21144101112016 @default.
- W2114410111 countsByYear W21144101112017 @default.
- W2114410111 countsByYear W21144101112018 @default.
- W2114410111 countsByYear W21144101112019 @default.
- W2114410111 countsByYear W21144101112020 @default.
- W2114410111 countsByYear W21144101112021 @default.
- W2114410111 countsByYear W21144101112022 @default.
- W2114410111 countsByYear W21144101112023 @default.
- W2114410111 crossrefType "journal-article" @default.
- W2114410111 hasAuthorship W2114410111A5000796046 @default.
- W2114410111 hasAuthorship W2114410111A5004022049 @default.
- W2114410111 hasAuthorship W2114410111A5056383381 @default.
- W2114410111 hasBestOaLocation W21144101111 @default.
- W2114410111 hasConcept C104317684 @default.
- W2114410111 hasConcept C118716 @default.
- W2114410111 hasConcept C11960822 @default.
- W2114410111 hasConcept C126619667 @default.
- W2114410111 hasConcept C143840085 @default.
- W2114410111 hasConcept C154428179 @default.
- W2114410111 hasConcept C181199279 @default.
- W2114410111 hasConcept C185592680 @default.
- W2114410111 hasConcept C190062978 @default.
- W2114410111 hasConcept C2777576037 @default.
- W2114410111 hasConcept C41625074 @default.
- W2114410111 hasConcept C55493867 @default.
- W2114410111 hasConcept C62478195 @default.
- W2114410111 hasConcept C86803240 @default.
- W2114410111 hasConcept C95444343 @default.
- W2114410111 hasConceptScore W2114410111C104317684 @default.
- W2114410111 hasConceptScore W2114410111C118716 @default.
- W2114410111 hasConceptScore W2114410111C11960822 @default.
- W2114410111 hasConceptScore W2114410111C126619667 @default.
- W2114410111 hasConceptScore W2114410111C143840085 @default.
- W2114410111 hasConceptScore W2114410111C154428179 @default.
- W2114410111 hasConceptScore W2114410111C181199279 @default.
- W2114410111 hasConceptScore W2114410111C185592680 @default.
- W2114410111 hasConceptScore W2114410111C190062978 @default.
- W2114410111 hasConceptScore W2114410111C2777576037 @default.
- W2114410111 hasConceptScore W2114410111C41625074 @default.
- W2114410111 hasConceptScore W2114410111C55493867 @default.
- W2114410111 hasConceptScore W2114410111C62478195 @default.
- W2114410111 hasConceptScore W2114410111C86803240 @default.