Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114495016> ?p ?o ?g. }
- W2114495016 endingPage "1069" @default.
- W2114495016 startingPage "1057" @default.
- W2114495016 abstract "Primary and secondary liver tumors resemble some of the most common causes of cancer and represent a major clinical problem owing to the poor prognosis. First-line therapeutic concepts are mainly based on surgical resection and/or systemic chemotherapy (SCT). However, many patients are not suitable for surgery or have failed SCT, although the total tumor load is still limited, which makes a regional therapy approach appealing.This review focuses on different types of transarterial instillation of chemotherapy, which encompasses conventional and drug-eluting transarterial chemoembolization (TACE), hepatic arterial infusion (HAI) chemotherapy and isolated hepatic perfusion (ILP).TACE can be regarded as the treatment of choice in patients with multinodular hepatocellular carcinoma, but it should still be performed as a lipiodol-based regimen, while the value of doxorubicin-eluting beads needs to be exploited in further randomized controlled trials (RCTs). For patients with colorectal liver metastases, HAI chemotherapy has been challenged by the advent of more effective SCT, but encouraging results have been observed for the combination of the most recent, active drugs given by means of HAI with SCT. Nevertheless, data from RCTs comparing SCT with this transarterial regional therapy approach, as well as with TACE and ILP, are urgently needed." @default.
- W2114495016 created "2016-06-24" @default.
- W2114495016 creator A5001670568 @default.
- W2114495016 creator A5057700552 @default.
- W2114495016 date "2011-04-21" @default.
- W2114495016 modified "2023-09-23" @default.
- W2114495016 title "Advances in regional chemotherapy of the liver" @default.
- W2114495016 cites W10475245 @default.
- W2114495016 cites W1586614077 @default.
- W2114495016 cites W1670652180 @default.
- W2114495016 cites W1835268604 @default.
- W2114495016 cites W1870066362 @default.
- W2114495016 cites W1878603103 @default.
- W2114495016 cites W1961040537 @default.
- W2114495016 cites W1963592300 @default.
- W2114495016 cites W1966468806 @default.
- W2114495016 cites W1969947714 @default.
- W2114495016 cites W1971837077 @default.
- W2114495016 cites W1975154077 @default.
- W2114495016 cites W1975496136 @default.
- W2114495016 cites W1975777455 @default.
- W2114495016 cites W1979423262 @default.
- W2114495016 cites W1979538908 @default.
- W2114495016 cites W1979780672 @default.
- W2114495016 cites W1980986964 @default.
- W2114495016 cites W1982527376 @default.
- W2114495016 cites W1985524610 @default.
- W2114495016 cites W1986924507 @default.
- W2114495016 cites W1990790427 @default.
- W2114495016 cites W1990921501 @default.
- W2114495016 cites W1991180701 @default.
- W2114495016 cites W1991227640 @default.
- W2114495016 cites W1994193851 @default.
- W2114495016 cites W1996869264 @default.
- W2114495016 cites W1999265843 @default.
- W2114495016 cites W2006519378 @default.
- W2114495016 cites W2007340624 @default.
- W2114495016 cites W2007615142 @default.
- W2114495016 cites W2009020951 @default.
- W2114495016 cites W2013065502 @default.
- W2114495016 cites W2020559266 @default.
- W2114495016 cites W2020830322 @default.
- W2114495016 cites W2021471642 @default.
- W2114495016 cites W2024270630 @default.
- W2114495016 cites W2025077625 @default.
- W2114495016 cites W2026140821 @default.
- W2114495016 cites W2029797721 @default.
- W2114495016 cites W2032794440 @default.
- W2114495016 cites W2033578575 @default.
- W2114495016 cites W2033703798 @default.
- W2114495016 cites W2039553930 @default.
- W2114495016 cites W2042470623 @default.
- W2114495016 cites W2043435446 @default.
- W2114495016 cites W2044224410 @default.
- W2114495016 cites W2048690087 @default.
- W2114495016 cites W2049811920 @default.
- W2114495016 cites W2050344385 @default.
- W2114495016 cites W2052552898 @default.
- W2114495016 cites W2054997051 @default.
- W2114495016 cites W2055647323 @default.
- W2114495016 cites W2056302939 @default.
- W2114495016 cites W2057408326 @default.
- W2114495016 cites W2057646027 @default.
- W2114495016 cites W2058693187 @default.
- W2114495016 cites W2063849195 @default.
- W2114495016 cites W2065565627 @default.
- W2114495016 cites W2066390717 @default.
- W2114495016 cites W2074333538 @default.
- W2114495016 cites W2075725415 @default.
- W2114495016 cites W2087450896 @default.
- W2114495016 cites W2087579890 @default.
- W2114495016 cites W2087923534 @default.
- W2114495016 cites W2090741805 @default.
- W2114495016 cites W2092759077 @default.
- W2114495016 cites W2092950906 @default.
- W2114495016 cites W2093869962 @default.
- W2114495016 cites W2094313851 @default.
- W2114495016 cites W2094618962 @default.
- W2114495016 cites W2095201384 @default.
- W2114495016 cites W2097440086 @default.
- W2114495016 cites W2109836271 @default.
- W2114495016 cites W2113058626 @default.
- W2114495016 cites W2113818241 @default.
- W2114495016 cites W2122364701 @default.
- W2114495016 cites W2124515527 @default.
- W2114495016 cites W2125737275 @default.
- W2114495016 cites W2125763116 @default.
- W2114495016 cites W2125877119 @default.
- W2114495016 cites W2128813634 @default.
- W2114495016 cites W2131239494 @default.
- W2114495016 cites W2133399075 @default.
- W2114495016 cites W2135423900 @default.
- W2114495016 cites W2137238918 @default.
- W2114495016 cites W2137493748 @default.
- W2114495016 cites W2138059780 @default.
- W2114495016 cites W2139296387 @default.
- W2114495016 cites W2142750088 @default.
- W2114495016 cites W2144425748 @default.