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- W2114501807 abstract "Condensation of tert-butyl (E)-3-(2′-aminophenyl)propenoate with a range of aromatic and heteroaromatic aldehydes gives the corresponding imines as single diastereoisomers (>98% de). Addition of lithium (R)-N-benzyl-N-(α-methylbenzyl)amide initiates a tandem conjugate addition/cyclization reaction to generate 2-aryl-4-aminotetrahydroquinoline-3-carboxylic acid derivatives in >98% de, >98% ee and high isolated yield. Hydrogenolysis of an N(1)-Boc protected derivative allows selective cleavage of the N-benzyl-N-α-methylbenzyl protecting groups without compromise of the diastereo- or enantiopurity." @default.
- W2114501807 created "2016-06-24" @default.
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- W2114501807 creator A5042218147 @default.
- W2114501807 date "2009-04-06" @default.
- W2114501807 modified "2023-09-27" @default.
- W2114501807 title "A Tandem Conjugate Addition/Cyclization Protocol for the Asymmetric Synthesis of 2-Aryl-4-aminotetrahydroquinoline-3-carboxylic Acid Derivatives" @default.
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- W2114501807 cites W1980985405 @default.
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- W2114501807 cites W1986762319 @default.
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- W2114501807 doi "https://doi.org/10.1021/ol9004118" @default.
- W2114501807 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19348467" @default.
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