Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114519789> ?p ?o ?g. }
- W2114519789 endingPage "1332" @default.
- W2114519789 startingPage "1325" @default.
- W2114519789 abstract "Several reports have suggested an increased risk of coronary disease in human immunodeficiency virus (HIV)-infected patients receiving protease inhibitors (PIs). Impaired endothelium-dependent vasodilation is a putative surrogate marker of coronary atherosclerotic disease.The present study evaluated the effect of HIV infection and antiretroviral treatment on endothelial vasomotor function, by assessing brachial artery flow-mediated dilation (FMD). A total of 75 HIV-infected patients were compared with 223 control subjects who were presumed to be HIV uninfected.HIV-infected patients had significantly impaired FMD, compared with control subjects (mean +/- SD, 7.3% +/- 4.4% vs. 11.1% +/- 6.3%; P < .0001). When adjustments were made for smoking status, sex, and body mass index, the difference between the 2 groups remained statistically significant (P < .01). In a cross-sectional analysis of the HIV-infected patients, we found significant associations between FMD and current injection drug use, hazardous drinking, HIV load, and alpha-high-density lipoprotein triglyceride levels, but not PI therapy. In a multivariate analysis, only current injection drug use and a lower alpha-high-density lipoprotein triglyceride level were significantly associated with FMD.HIV-infected patients have significant impairment of endothelial function, and this impairment is worse among those with elevated levels of HIV replication, particularly injection drug users." @default.
- W2114519789 created "2016-06-24" @default.
- W2114519789 creator A5013031763 @default.
- W2114519789 creator A5036639406 @default.
- W2114519789 creator A5036782519 @default.
- W2114519789 creator A5055974859 @default.
- W2114519789 creator A5058063837 @default.
- W2114519789 creator A5071378911 @default.
- W2114519789 creator A5085234321 @default.
- W2114519789 date "2006-05-01" @default.
- W2114519789 modified "2023-10-13" @default.
- W2114519789 title "Endothelial Function in HIV-Infected Persons" @default.
- W2114519789 cites W146196984 @default.
- W2114519789 cites W1542622008 @default.
- W2114519789 cites W173272028 @default.
- W2114519789 cites W1964510458 @default.
- W2114519789 cites W1975475560 @default.
- W2114519789 cites W1976642547 @default.
- W2114519789 cites W1979252165 @default.
- W2114519789 cites W1979625649 @default.
- W2114519789 cites W1980445357 @default.
- W2114519789 cites W1982811953 @default.
- W2114519789 cites W1991844886 @default.
- W2114519789 cites W1992488558 @default.
- W2114519789 cites W1996385661 @default.
- W2114519789 cites W1999419730 @default.
- W2114519789 cites W2000219564 @default.
- W2114519789 cites W2003358339 @default.
- W2114519789 cites W2008791277 @default.
- W2114519789 cites W2010352983 @default.
- W2114519789 cites W2014859893 @default.
- W2114519789 cites W2015931028 @default.
- W2114519789 cites W2017131494 @default.
- W2114519789 cites W2017306262 @default.
- W2114519789 cites W2028657303 @default.
- W2114519789 cites W2043262912 @default.
- W2114519789 cites W2052185360 @default.
- W2114519789 cites W2060210361 @default.
- W2114519789 cites W2060825301 @default.
- W2114519789 cites W2078529164 @default.
- W2114519789 cites W2087087045 @default.
- W2114519789 cites W2089657864 @default.
- W2114519789 cites W2113082835 @default.
- W2114519789 cites W2120532138 @default.
- W2114519789 cites W2136385005 @default.
- W2114519789 cites W2136390349 @default.
- W2114519789 cites W2146111340 @default.
- W2114519789 cites W2152464646 @default.
- W2114519789 cites W2153683121 @default.
- W2114519789 cites W2157138119 @default.
- W2114519789 cites W2168784348 @default.
- W2114519789 cites W2309506771 @default.
- W2114519789 cites W2318289184 @default.
- W2114519789 cites W2324473093 @default.
- W2114519789 cites W2338565293 @default.
- W2114519789 cites W24373389 @default.
- W2114519789 cites W4230870013 @default.
- W2114519789 cites W4254603647 @default.
- W2114519789 doi "https://doi.org/10.1086/503261" @default.
- W2114519789 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2737346" @default.
- W2114519789 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16586393" @default.
- W2114519789 hasPublicationYear "2006" @default.
- W2114519789 type Work @default.
- W2114519789 sameAs 2114519789 @default.
- W2114519789 citedByCount "184" @default.
- W2114519789 countsByYear W21145197892012 @default.
- W2114519789 countsByYear W21145197892013 @default.
- W2114519789 countsByYear W21145197892014 @default.
- W2114519789 countsByYear W21145197892015 @default.
- W2114519789 countsByYear W21145197892016 @default.
- W2114519789 countsByYear W21145197892017 @default.
- W2114519789 countsByYear W21145197892018 @default.
- W2114519789 countsByYear W21145197892019 @default.
- W2114519789 countsByYear W21145197892020 @default.
- W2114519789 countsByYear W21145197892021 @default.
- W2114519789 countsByYear W21145197892022 @default.
- W2114519789 countsByYear W21145197892023 @default.
- W2114519789 crossrefType "journal-article" @default.
- W2114519789 hasAuthorship W2114519789A5013031763 @default.
- W2114519789 hasAuthorship W2114519789A5036639406 @default.
- W2114519789 hasAuthorship W2114519789A5036782519 @default.
- W2114519789 hasAuthorship W2114519789A5055974859 @default.
- W2114519789 hasAuthorship W2114519789A5058063837 @default.
- W2114519789 hasAuthorship W2114519789A5071378911 @default.
- W2114519789 hasAuthorship W2114519789A5085234321 @default.
- W2114519789 hasBestOaLocation W21145197891 @default.
- W2114519789 hasConcept C126322002 @default.
- W2114519789 hasConcept C142462285 @default.
- W2114519789 hasConcept C203014093 @default.
- W2114519789 hasConcept C2776992346 @default.
- W2114519789 hasConcept C2777604165 @default.
- W2114519789 hasConcept C2778163477 @default.
- W2114519789 hasConcept C2778213512 @default.
- W2114519789 hasConcept C2778913445 @default.
- W2114519789 hasConcept C2780072125 @default.
- W2114519789 hasConcept C2780221984 @default.
- W2114519789 hasConcept C2780972559 @default.
- W2114519789 hasConcept C3013748606 @default.