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- W2114531913 abstract "Pre- and post-treatment serum thrombopoietin (TPO) concentration was measured in 35 patients with immune thrombocytopenic purpura (ITP). Mean post-treatment levels were significantly lower (P = 0·02) than pretreatment and not different for treatment modality. No significant correlation between pre- or post-treatment TPO and platelet counts was demonstrable (R = −0·325, P = 0·056 and R = −0·227, P = 0·190 respectively). In patients with very low platelet counts ( 20 × 109/l), pretreatment serum TPO was significantly higher than in patients with higher counts (P = 0·033). The logarithm of the platelet turnover rate, measured in 15 patients, correlated with pretreatment TPO levels (R = 0·64). These findings suggest a contributory role for TPO in the mechanism of ITP." @default.
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- W2114531913 date "2001-12-01" @default.
- W2114531913 modified "2023-10-17" @default.
- W2114531913 title "Serum thrombopoietin levels in relation to disease status in patients with immune thrombocytopenic purpura" @default.
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- W2114531913 doi "https://doi.org/10.1046/j.1365-2141.2001.03184.x" @default.
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