Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114536730> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2114536730 abstract "Objectives. To determine the gastroprotective and antisecretory effect of ethanol extract from matico leaves (Piper aduncum) in animal models. Materials and methods. To evaluate the gastroprotective effect, 220 mice of the Balb C57 strain were used. They were randomized in 22 groups of ten animals each, in which the formation of gastric ulcers was induced with indomethacin. Gastroprotection was determined by evaluating three aspects: inflammation, number of hemorrhagic shocks and number of ulcers. To evaluate the antisecretory effect, 64 white male Holtzman rats were used, which were randomized in eight groups of eight animals, one control and seven groups of treatment with one extract dose level and two phytochemical dose levels. Antisecretion was obtained through the pylorus ligation. Results. Regarding gastroprotection, dichloromethane, chloroform, hexane and methanol extracts decreased inflammation to over 66% (p<0,05). The ethanolic extract shows 100% activity in reducing the number of hemorrhagic bands (p<0,05). The chloroform extract shows antiulcer activity at 75% (p<0,05). In terms of antisecretion, the phytochemical in capsules containing the ethanolic extract achieved 72% reduction of the gastric secretion volume (p<0,01) and 104,3% (p<0,01) PH increase. Conclusions. In experimental conditions, ethanolic extracts, their fractions and phytochemicals have a gastroprotective effect in mice and antisecretory effect in rats." @default.
- W2114536730 created "2016-06-24" @default.
- W2114536730 creator A5008343188 @default.
- W2114536730 creator A5026789423 @default.
- W2114536730 creator A5032938827 @default.
- W2114536730 creator A5044261195 @default.
- W2114536730 creator A5049330619 @default.
- W2114536730 creator A5051732361 @default.
- W2114536730 creator A5055095929 @default.
- W2114536730 creator A5056811548 @default.
- W2114536730 creator A5064766015 @default.
- W2114536730 date "2014-03-11" @default.
- W2114536730 modified "2023-09-23" @default.
- W2114536730 title "Efecto gastroprotector y antisecretor de un fitofármaco de hojas de matico (Piper aduncum)" @default.
- W2114536730 cites W1554897248 @default.
- W2114536730 cites W1576054536 @default.
- W2114536730 cites W1973843410 @default.
- W2114536730 cites W1991317722 @default.
- W2114536730 cites W1994139148 @default.
- W2114536730 cites W1995507287 @default.
- W2114536730 cites W2014085190 @default.
- W2114536730 cites W2023417128 @default.
- W2114536730 cites W2026639275 @default.
- W2114536730 cites W2028986035 @default.
- W2114536730 cites W2029758945 @default.
- W2114536730 cites W2061396218 @default.
- W2114536730 cites W2069076162 @default.
- W2114536730 cites W2071903946 @default.
- W2114536730 cites W2073518752 @default.
- W2114536730 cites W2078554972 @default.
- W2114536730 cites W2086574041 @default.
- W2114536730 cites W2108594592 @default.
- W2114536730 cites W2225439238 @default.
- W2114536730 cites W2302752766 @default.
- W2114536730 cites W335354783 @default.
- W2114536730 cites W984964308 @default.
- W2114536730 cites W2336313712 @default.
- W2114536730 doi "https://doi.org/10.17843/rpmesp.2013.304.240" @default.
- W2114536730 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24448937" @default.
- W2114536730 hasPublicationYear "2014" @default.
- W2114536730 type Work @default.
- W2114536730 sameAs 2114536730 @default.
- W2114536730 citedByCount "3" @default.
- W2114536730 countsByYear W21145367302014 @default.
- W2114536730 countsByYear W21145367302015 @default.
- W2114536730 countsByYear W21145367302021 @default.
- W2114536730 crossrefType "journal-article" @default.
- W2114536730 hasAuthorship W2114536730A5008343188 @default.
- W2114536730 hasAuthorship W2114536730A5026789423 @default.
- W2114536730 hasAuthorship W2114536730A5032938827 @default.
- W2114536730 hasAuthorship W2114536730A5044261195 @default.
- W2114536730 hasAuthorship W2114536730A5049330619 @default.
- W2114536730 hasAuthorship W2114536730A5051732361 @default.
- W2114536730 hasAuthorship W2114536730A5055095929 @default.
- W2114536730 hasAuthorship W2114536730A5056811548 @default.
- W2114536730 hasAuthorship W2114536730A5064766015 @default.
- W2114536730 hasBestOaLocation W21145367301 @default.
- W2114536730 hasConcept C142724271 @default.
- W2114536730 hasConcept C185592680 @default.
- W2114536730 hasConcept C195475562 @default.
- W2114536730 hasConcept C204787440 @default.
- W2114536730 hasConcept C2777155639 @default.
- W2114536730 hasConcept C2779969877 @default.
- W2114536730 hasConcept C556039675 @default.
- W2114536730 hasConcept C71924100 @default.
- W2114536730 hasConcept C98274493 @default.
- W2114536730 hasConceptScore W2114536730C142724271 @default.
- W2114536730 hasConceptScore W2114536730C185592680 @default.
- W2114536730 hasConceptScore W2114536730C195475562 @default.
- W2114536730 hasConceptScore W2114536730C204787440 @default.
- W2114536730 hasConceptScore W2114536730C2777155639 @default.
- W2114536730 hasConceptScore W2114536730C2779969877 @default.
- W2114536730 hasConceptScore W2114536730C556039675 @default.
- W2114536730 hasConceptScore W2114536730C71924100 @default.
- W2114536730 hasConceptScore W2114536730C98274493 @default.
- W2114536730 hasIssue "4" @default.
- W2114536730 hasLocation W21145367301 @default.
- W2114536730 hasLocation W21145367302 @default.
- W2114536730 hasLocation W21145367303 @default.
- W2114536730 hasLocation W21145367304 @default.
- W2114536730 hasOpenAccess W2114536730 @default.
- W2114536730 hasPrimaryLocation W21145367301 @default.
- W2114536730 hasRelatedWork W2097045984 @default.
- W2114536730 hasRelatedWork W2320344009 @default.
- W2114536730 hasRelatedWork W2493117472 @default.
- W2114536730 hasRelatedWork W2725927837 @default.
- W2114536730 hasRelatedWork W2972395592 @default.
- W2114536730 hasRelatedWork W3091946903 @default.
- W2114536730 hasRelatedWork W3107587590 @default.
- W2114536730 hasRelatedWork W3130821936 @default.
- W2114536730 hasRelatedWork W3176039872 @default.
- W2114536730 hasRelatedWork W4301048464 @default.
- W2114536730 hasVolume "30" @default.
- W2114536730 isParatext "false" @default.
- W2114536730 isRetracted "false" @default.
- W2114536730 magId "2114536730" @default.
- W2114536730 workType "article" @default.