FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114542372> ?p ?o ?g. }

• W2114542372 abstract "Abstract Background Although 2-20% of breast cancer patients develop a contralateral breast cancer (CBC), prognosis after CBC is still debated. Using a unique patient cohort, we have investigated whether time interval to second breast cancer (BC2) and mode of detection are associated to prognosis. Methods Information on patient-, tumour-, treatment-characteristics, and outcome was abstracted from patients' individual charts for all patients diagnosed with metachronous CBC in the Southern Healthcare Region of Sweden from 1977-2007. Distant disease-free survival (DDFS) and risk of distant metastases were primary endpoints. Results The cohort included 723 patients with metachronous contralateral breast cancer as primary breast cancer event. Patients with less than three years to BC2 had a significantly impaired DDFS (p = 0.01), and in sub-group analysis, this effect was seen primarily in patients aged <50. By logistic regression analysis, patients diagnosed with BC2 within routine follow-up examinations had a significantly lower risk of developing metastases compared to those who were symptomatic at diagnosis (p < 0.0001). Chemotherapy given after breast BC1 was a negative prognostic factor for DDFS, whereas endocrine treatment and radiotherapy given after BC2 improved DDFS. Conclusions In a large cohort of patients with CBC, we found the time interval to BC2 to be a strong prognostic factor for DDFS in young women and mode of detection to be related to risk of distant metastases. Future studies of tumour biology of BC2 in relation to prognostic factors found in the present study can hopefully provide biological explanations to these findings." @default.
• W2114542372 created "2016-06-24" @default.
• W2114542372 creator A5010340306 @default.
• W2114542372 creator A5024663234 @default.
• W2114542372 creator A5044494492 @default.
• W2114542372 creator A5061921179 @default.
• W2114542372 creator A5081518006 @default.
• W2114542372 date "2011-03-30" @default.
• W2114542372 modified "2023-10-14" @default.
• W2114542372 title "Prediction of outcome after diagnosis of metachronous contralateral breast cancer" @default.
• W2114542372 cites W1525318852 @default.
• W2114542372 cites W1972923779 @default.
• W2114542372 cites W1975810712 @default.
• W2114542372 cites W1978282886 @default.
• W2114542372 cites W1981914307 @default.
• W2114542372 cites W1984684780 @default.
• W2114542372 cites W1989289006 @default.
• W2114542372 cites W1997756362 @default.
• W2114542372 cites W2003726111 @default.
• W2114542372 cites W2004864041 @default.
• W2114542372 cites W2015692376 @default.
• W2114542372 cites W2028404896 @default.
• W2114542372 cites W2028431242 @default.
• W2114542372 cites W2032602380 @default.
• W2114542372 cites W2033364004 @default.
• W2114542372 cites W2042752971 @default.
• W2114542372 cites W2044974380 @default.
• W2114542372 cites W2050867005 @default.
• W2114542372 cites W2057263737 @default.
• W2114542372 cites W2084116621 @default.
• W2114542372 cites W2091001821 @default.
• W2114542372 cites W2093172358 @default.
• W2114542372 cites W2096366696 @default.
• W2114542372 cites W2098565096 @default.
• W2114542372 cites W2098945202 @default.
• W2114542372 cites W2100790158 @default.
• W2114542372 cites W2105442326 @default.
• W2114542372 cites W2117676051 @default.
• W2114542372 cites W2117873981 @default.
• W2114542372 cites W2120065707 @default.
• W2114542372 cites W2121656289 @default.
• W2114542372 cites W2125623465 @default.
• W2114542372 cites W2126301927 @default.
• W2114542372 cites W2145482850 @default.
• W2114542372 cites W2149733477 @default.
• W2114542372 cites W2156746273 @default.
• W2114542372 cites W2161782612 @default.
• W2114542372 cites W2164353984 @default.
• W2114542372 cites W2166631738 @default.
• W2114542372 cites W4237553706 @default.
• W2114542372 doi "https://doi.org/10.1186/1471-2407-11-114" @default.
• W2114542372 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3080341" @default.
• W2114542372 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21450091" @default.
• W2114542372 hasPublicationYear "2011" @default.
• W2114542372 type Work @default.
• W2114542372 sameAs 2114542372 @default.
• W2114542372 citedByCount "34" @default.
• W2114542372 countsByYear W21145423722012 @default.
• W2114542372 countsByYear W21145423722013 @default.
• W2114542372 countsByYear W21145423722014 @default.
• W2114542372 countsByYear W21145423722015 @default.
• W2114542372 countsByYear W21145423722016 @default.
• W2114542372 countsByYear W21145423722017 @default.
• W2114542372 countsByYear W21145423722018 @default.
• W2114542372 countsByYear W21145423722019 @default.
• W2114542372 countsByYear W21145423722020 @default.
• W2114542372 countsByYear W21145423722021 @default.
• W2114542372 countsByYear W21145423722022 @default.
• W2114542372 countsByYear W21145423722023 @default.
• W2114542372 crossrefType "journal-article" @default.
• W2114542372 hasAuthorship W2114542372A5010340306 @default.
• W2114542372 hasAuthorship W2114542372A5024663234 @default.
• W2114542372 hasAuthorship W2114542372A5044494492 @default.
• W2114542372 hasAuthorship W2114542372A5061921179 @default.
• W2114542372 hasAuthorship W2114542372A5081518006 @default.
• W2114542372 hasBestOaLocation W21145423721 @default.
• W2114542372 hasConcept C121608353 @default.
• W2114542372 hasConcept C126322002 @default.
• W2114542372 hasConcept C143998085 @default.
• W2114542372 hasConcept C151956035 @default.
• W2114542372 hasConcept C167135981 @default.
• W2114542372 hasConcept C201903717 @default.
• W2114542372 hasConcept C2779134260 @default.
• W2114542372 hasConcept C2780140570 @default.
• W2114542372 hasConcept C509974204 @default.
• W2114542372 hasConcept C530470458 @default.
• W2114542372 hasConcept C71924100 @default.
• W2114542372 hasConcept C72563966 @default.
• W2114542372 hasConceptScore W2114542372C121608353 @default.
• W2114542372 hasConceptScore W2114542372C126322002 @default.
• W2114542372 hasConceptScore W2114542372C143998085 @default.
• W2114542372 hasConceptScore W2114542372C151956035 @default.
• W2114542372 hasConceptScore W2114542372C167135981 @default.
• W2114542372 hasConceptScore W2114542372C201903717 @default.
• W2114542372 hasConceptScore W2114542372C2779134260 @default.
• W2114542372 hasConceptScore W2114542372C2780140570 @default.
• W2114542372 hasConceptScore W2114542372C509974204 @default.
• W2114542372 hasConceptScore W2114542372C530470458 @default.
• W2114542372 hasConceptScore W2114542372C71924100 @default.
• W2114542372 hasConceptScore W2114542372C72563966 @default.

• next