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- W2114556977 abstract "microRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs, approximately 22 nucleotides (nts) in length, widely found in animals, plants, and viruses. Mature miRNAs control gene expression at a post-transcriptional level through blocking protein translation or inducing mRNA degradation. Many recent studies have shown that hepatitis B virus x protein (HBx), a viral protein with a crucial role in hepatogenesis, is associated with the regulation of miRNAs. This interaction impacts fundamental tumor processes, such as cell proliferation, differentiation, and apoptosis. In this review, we summarized the recent literature on the roles of HBx-regulated miRNAs in the pathogenesis of hepatocellular carcinoma." @default.
- W2114556977 created "2016-06-24" @default.
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- W2114556977 date "2014-10-07" @default.
- W2114556977 modified "2023-10-16" @default.
- W2114556977 title "The impact of hepatitis B virus x protein and microRNAs in hepatocellular carcinoma: a comprehensive analysis" @default.
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- W2114556977 doi "https://doi.org/10.1007/s13277-014-2658-6" @default.
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