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• W2114597244 abstract "The transformation of cultivated hamster brain cells by polyoma virus is reported. The transformed cell line contained polyoma virus-specific nuclear, surface and transplantation antigens. Subcutaneous and intracranial inoculations revealed high tumorigenicity of the cells. Brain-specific S 100 protein was found in these tumors with immuno-peroxidase staining, suggesting that they were of a nervous nature. Both in vivo and in vitro, the cells had glial features as studied by phase contrast, light and electron microscopy. Type-H virus-like particles were found in the tumor cells and might have played a role in the viral transformation." @default.
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• W2114597244 date "1978-04-15" @default.
• W2114597244 modified "2023-09-23" @default.
• W2114597244 title "Neoplastic transformation of hamster brain cellsin vitro by polyoma virus" @default.
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• W2114597244 doi "https://doi.org/10.1002/ijc.2910210419" @default.
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