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- W2114653999 abstract "It is clear that cytokines exert a variety of modulatory actions on the central nervous system. As part of our work exploring the relationship between immune activation and psychosis, we measured cerebrospinal fluid (CSF) IL-1α and IL-2 levels in 60 medicated schizophrenic patients and in 21 normal volunteers using a competitive enzyme immunoassay. The two groups did not differ significantly in their mean cytokine levels: 1.01 (0.149) ng/ml (patients) vs. 1.28 (0.150) ng/ml (controls) for IL-1α and 0.970 (0.038) ng/ml (patients) vs. 1.25 (0.086) ng/ml (controls) for IL-2. There was a significant positive correlation between CSF IL-1α and IL-2 levels for all subjects (r = 0.50, n=44, p = 0.0001)." @default.
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- W2114653999 date "1997-05-01" @default.
- W2114653999 modified "2023-10-11" @default.
- W2114653999 title "CSF IL-1 and IL-2 in medicated schizophrenic patients and normal volunteers" @default.
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- W2114653999 doi "https://doi.org/10.1016/s0920-9964(97)00008-x" @default.
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