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- W2114661303 abstract "Objectives: Late-life implications of early traumatic stress for the adreno-cortical system were examined in a sample of 133 child survivors of the Holocaust, who were subjected to Nazi persecution during infancy. Method: In a non-convenience sample of child survivors, born between 1935 and 1944, basal circadian cortisol release and cortisol reactivity to a stressor were assessed. Results: Age, parental loss during the Holocaust, current depression, post-traumatic stress disorder (PTSD) and physical illness were not associated with differences in basal diurnal cortisol levels. Neuro-endocrine effects, however, were found in stress reactivity through elevated cortisol levels in male respondents in the youngest age group (born 1941–1945), and in male respondents suffering from PTSD-related functional impairment. Conclusion: The youngest survivors of Nazi persecution show late-life effects of traumatic stress during early childhood, evidenced by the early onset of differential neuroendocrine pathways to stress-regulating strategies." @default.
- W2114661303 created "2016-06-24" @default.
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- W2114661303 date "2008-09-01" @default.
- W2114661303 modified "2023-09-26" @default.
- W2114661303 title "Diurnal cortisol patterns and stress reactivity in child Holocaust survivors reaching old age" @default.
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- W2114661303 doi "https://doi.org/10.1080/13607860802343134" @default.
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