Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114743310> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2114743310 endingPage "283" @default.
- W2114743310 startingPage "279" @default.
- W2114743310 abstract "Brentuximab vendotin is a monoclonal antibody approved in August 2011 for use in patients with Hodgkin disease and a rare systemic lymphoma known as anaplastic large cell lymphoma. Brentuximab is approved in patients with Hodgkin disease who have failed autologous transplantation or after failure of at least two prior multi-agent chemotherapy regimens but has not been studied following allogeneic transplantation. Four patients with relapsed Hodgkin disease have been treated at our institution with at least two doses of brentuximab vendotin. Two patients have experienced significant infusion reactions on multiple occasions, and two patients have tolerated the infusions well. During phase 2 trials, there were no reports of Grade 3 or 4 infusion-related reactions. Both patients with reactions had relapsed following allogeneic stem cell transplants, while neither of the patients who tolerated the infusions had undergone transplantation. We report our experience with brentuximab vendotin-treated patients at our institution, focusing on the two post-allogeneic patients who experienced multiple significant infusion reactions. This report evaluates possible mechanisms behind their reactions, including previous allogeneic stem cell transplantation as a likely precipitating factor." @default.
- W2114743310 created "2016-06-24" @default.
- W2114743310 creator A5001417224 @default.
- W2114743310 creator A5007273172 @default.
- W2114743310 creator A5028853453 @default.
- W2114743310 creator A5033702562 @default.
- W2114743310 creator A5035166504 @default.
- W2114743310 date "2012-11-15" @default.
- W2114743310 modified "2023-09-27" @default.
- W2114743310 title "Severe infusion reactions to brentuximab vedotin in two patients with Hodgkin lymphoma previously treated with allogeneic stem cell transplantation" @default.
- W2114743310 cites W1528353570 @default.
- W2114743310 cites W1544569979 @default.
- W2114743310 cites W1880801097 @default.
- W2114743310 cites W1914489852 @default.
- W2114743310 cites W1989545023 @default.
- W2114743310 cites W2004961788 @default.
- W2114743310 cites W2026373761 @default.
- W2114743310 cites W2030604335 @default.
- W2114743310 cites W2046667779 @default.
- W2114743310 cites W2050105922 @default.
- W2114743310 cites W2082635925 @default.
- W2114743310 cites W2102517064 @default.
- W2114743310 cites W2104221398 @default.
- W2114743310 cites W2106555579 @default.
- W2114743310 cites W2055727816 @default.
- W2114743310 doi "https://doi.org/10.1177/1078155212464021" @default.
- W2114743310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23154572" @default.
- W2114743310 hasPublicationYear "2012" @default.
- W2114743310 type Work @default.
- W2114743310 sameAs 2114743310 @default.
- W2114743310 citedByCount "11" @default.
- W2114743310 countsByYear W21147433102013 @default.
- W2114743310 countsByYear W21147433102014 @default.
- W2114743310 countsByYear W21147433102015 @default.
- W2114743310 countsByYear W21147433102017 @default.
- W2114743310 countsByYear W21147433102023 @default.
- W2114743310 crossrefType "journal-article" @default.
- W2114743310 hasAuthorship W2114743310A5001417224 @default.
- W2114743310 hasAuthorship W2114743310A5007273172 @default.
- W2114743310 hasAuthorship W2114743310A5028853453 @default.
- W2114743310 hasAuthorship W2114743310A5033702562 @default.
- W2114743310 hasAuthorship W2114743310A5035166504 @default.
- W2114743310 hasConcept C126322002 @default.
- W2114743310 hasConcept C141071460 @default.
- W2114743310 hasConcept C143998085 @default.
- W2114743310 hasConcept C2776694085 @default.
- W2114743310 hasConcept C2777872185 @default.
- W2114743310 hasConcept C2778191690 @default.
- W2114743310 hasConcept C2779050716 @default.
- W2114743310 hasConcept C2779134260 @default.
- W2114743310 hasConcept C2779338263 @default.
- W2114743310 hasConcept C28328180 @default.
- W2114743310 hasConcept C2911091166 @default.
- W2114743310 hasConcept C2992779791 @default.
- W2114743310 hasConcept C54355233 @default.
- W2114743310 hasConcept C71924100 @default.
- W2114743310 hasConcept C86803240 @default.
- W2114743310 hasConceptScore W2114743310C126322002 @default.
- W2114743310 hasConceptScore W2114743310C141071460 @default.
- W2114743310 hasConceptScore W2114743310C143998085 @default.
- W2114743310 hasConceptScore W2114743310C2776694085 @default.
- W2114743310 hasConceptScore W2114743310C2777872185 @default.
- W2114743310 hasConceptScore W2114743310C2778191690 @default.
- W2114743310 hasConceptScore W2114743310C2779050716 @default.
- W2114743310 hasConceptScore W2114743310C2779134260 @default.
- W2114743310 hasConceptScore W2114743310C2779338263 @default.
- W2114743310 hasConceptScore W2114743310C28328180 @default.
- W2114743310 hasConceptScore W2114743310C2911091166 @default.
- W2114743310 hasConceptScore W2114743310C2992779791 @default.
- W2114743310 hasConceptScore W2114743310C54355233 @default.
- W2114743310 hasConceptScore W2114743310C71924100 @default.
- W2114743310 hasConceptScore W2114743310C86803240 @default.
- W2114743310 hasIssue "3" @default.
- W2114743310 hasLocation W21147433101 @default.
- W2114743310 hasLocation W21147433102 @default.
- W2114743310 hasOpenAccess W2114743310 @default.
- W2114743310 hasPrimaryLocation W21147433101 @default.
- W2114743310 hasRelatedWork W2051094031 @default.
- W2114743310 hasRelatedWork W2059846794 @default.
- W2114743310 hasRelatedWork W2091104789 @default.
- W2114743310 hasRelatedWork W2149135951 @default.
- W2114743310 hasRelatedWork W2549051694 @default.
- W2114743310 hasRelatedWork W2792791166 @default.
- W2114743310 hasRelatedWork W2941198138 @default.
- W2114743310 hasRelatedWork W3043630561 @default.
- W2114743310 hasRelatedWork W4230483407 @default.
- W2114743310 hasRelatedWork W4310104180 @default.
- W2114743310 hasVolume "19" @default.
- W2114743310 isParatext "false" @default.
- W2114743310 isRetracted "false" @default.
- W2114743310 magId "2114743310" @default.
- W2114743310 workType "article" @default.