FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114789627> ?p ?o ?g. }

• W2114789627 endingPage "6733" @default.
• W2114789627 startingPage "6728" @default.
• W2114789627 abstract "ABSTRACT Human anaplasmosis (formerly human granulocytic ehrlichiosis) and human monocytic ehrlichiosis (HME) are emerging tick-borne infections caused by obligate intracellular bacteria in the family Anaplasmataceae . Clinical findings include fever, headache, myalgia, leukopenia, thrombocytopenia, and hepatic inflammatory injury. Whereas Ehrlichia chaffeensis (HME) often causes meningoencephalitis, this is rare with Anaplasma phagocytophilum infection. The abilities of infected primary host monocytes and neutrophils and of infected HL-60 cells to cross human umbilical vein endothelial cell-derived EA.hy926 cell barriers and human brain microvascular cells (BMEC), a human blood-brain barrier model, were studied. Uninfected monocyte/macrophages crossed endothelial cell barriers six times more efficiently than neutrophils. More E. chaffeensis -infected monocytes transmigrated than uninfected monocytes, whereas A. phagocytophilum suppressed neutrophil transmigration. Differences were not due to barrier dysfunction, as transendothelial cell resistivities were the same for uninfected cell controls. Similar results were obtained for HL-60 cells used as hosts for E. chaffeensis and A. phagocytophilum . Differential transmigration of E. chaffeensis- and A. phagocytophilum -infected leukocytes and HL-60 cells confirmed a role for the pathogen in modifying cell migratory capacity. These results support the hypothesis that Anaplasmataceae intracellular infections lead to unique pathogen-specific host cell functional alterations that are likely important for pathogen survival, pathogenesis, and disease induction." @default.
• W2114789627 created "2016-06-24" @default.
• W2114789627 creator A5003749380 @default.
• W2114789627 creator A5040424012 @default.
• W2114789627 creator A5042852035 @default.
• W2114789627 creator A5065231641 @default.
• W2114789627 date "2003-12-01" @default.
• W2114789627 modified "2023-10-01" @default.
• W2114789627 title "Divergent Interactions of<i>Ehrlichiachaffeensis-</i>and<i>Anaplasma phagocytophilum-</i>InfectedLeukocytes with Endothelial CellBarriers" @default.
• W2114789627 cites W1602508363 @default.
• W2114789627 cites W1864853792 @default.
• W2114789627 cites W1910966691 @default.
• W2114789627 cites W1915335956 @default.
• W2114789627 cites W1970148498 @default.
• W2114789627 cites W1986722064 @default.
• W2114789627 cites W2000441131 @default.
• W2114789627 cites W2029231398 @default.
• W2114789627 cites W2037548392 @default.
• W2114789627 cites W2042091261 @default.
• W2114789627 cites W2054927308 @default.
• W2114789627 cites W2064740336 @default.
• W2114789627 cites W2070207411 @default.
• W2114789627 cites W2071583315 @default.
• W2114789627 cites W2090052676 @default.
• W2114789627 cites W2096015856 @default.
• W2114789627 cites W2103097492 @default.
• W2114789627 cites W2104840825 @default.
• W2114789627 cites W2107146480 @default.
• W2114789627 cites W2119499389 @default.
• W2114789627 cites W2120295864 @default.
• W2114789627 cites W2120786836 @default.
• W2114789627 cites W2128746435 @default.
• W2114789627 cites W2131091712 @default.
• W2114789627 cites W2131184698 @default.
• W2114789627 cites W2132854225 @default.
• W2114789627 cites W2133552199 @default.
• W2114789627 cites W2143764497 @default.
• W2114789627 cites W2146582952 @default.
• W2114789627 cites W2149071352 @default.
• W2114789627 cites W2153213171 @default.
• W2114789627 cites W2166704438 @default.
• W2114789627 cites W2166833739 @default.
• W2114789627 cites W2186849444 @default.
• W2114789627 cites W39020522 @default.
• W2114789627 cites W4232646680 @default.
• W2114789627 cites W4320578718 @default.
• W2114789627 doi "https://doi.org/10.1128/iai.71.12.6728-6733.2003" @default.
• W2114789627 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/308917" @default.
• W2114789627 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14638757" @default.
• W2114789627 hasPublicationYear "2003" @default.
• W2114789627 type Work @default.
• W2114789627 sameAs 2114789627 @default.
• W2114789627 citedByCount "17" @default.
• W2114789627 countsByYear W21147896272012 @default.
• W2114789627 countsByYear W21147896272014 @default.
• W2114789627 countsByYear W21147896272018 @default.
• W2114789627 countsByYear W21147896272019 @default.
• W2114789627 countsByYear W21147896272020 @default.
• W2114789627 countsByYear W21147896272023 @default.
• W2114789627 crossrefType "journal-article" @default.
• W2114789627 hasAuthorship W2114789627A5003749380 @default.
• W2114789627 hasAuthorship W2114789627A5040424012 @default.
• W2114789627 hasAuthorship W2114789627A5042852035 @default.
• W2114789627 hasAuthorship W2114789627A5065231641 @default.
• W2114789627 hasBestOaLocation W21147896271 @default.
• W2114789627 hasConcept C153726182 @default.
• W2114789627 hasConcept C159047783 @default.
• W2114789627 hasConcept C159654299 @default.
• W2114789627 hasConcept C203014093 @default.
• W2114789627 hasConcept C2776370125 @default.
• W2114789627 hasConcept C2776460866 @default.
• W2114789627 hasConcept C2777479583 @default.
• W2114789627 hasConcept C2777511614 @default.
• W2114789627 hasConcept C2778101375 @default.
• W2114789627 hasConcept C2779159148 @default.
• W2114789627 hasConcept C2779620486 @default.
• W2114789627 hasConcept C2779657035 @default.
• W2114789627 hasConcept C2909063110 @default.
• W2114789627 hasConcept C86803240 @default.
• W2114789627 hasConcept C8891405 @default.
• W2114789627 hasConcept C89423630 @default.
• W2114789627 hasConceptScore W2114789627C153726182 @default.
• W2114789627 hasConceptScore W2114789627C159047783 @default.
• W2114789627 hasConceptScore W2114789627C159654299 @default.
• W2114789627 hasConceptScore W2114789627C203014093 @default.
• W2114789627 hasConceptScore W2114789627C2776370125 @default.
• W2114789627 hasConceptScore W2114789627C2776460866 @default.
• W2114789627 hasConceptScore W2114789627C2777479583 @default.
• W2114789627 hasConceptScore W2114789627C2777511614 @default.
• W2114789627 hasConceptScore W2114789627C2778101375 @default.
• W2114789627 hasConceptScore W2114789627C2779159148 @default.
• W2114789627 hasConceptScore W2114789627C2779620486 @default.
• W2114789627 hasConceptScore W2114789627C2779657035 @default.
• W2114789627 hasConceptScore W2114789627C2909063110 @default.
• W2114789627 hasConceptScore W2114789627C86803240 @default.
• W2114789627 hasConceptScore W2114789627C8891405 @default.
• W2114789627 hasConceptScore W2114789627C89423630 @default.
• W2114789627 hasIssue "12" @default.

• next