FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114824633> ?p ?o ?g. }

• W2114824633 endingPage "9517" @default.
• W2114824633 startingPage "9517" @default.
• W2114824633 abstract "Biodegradable metal alloys emerge as a new class of biomaterials for tissue engineering and medical devices such as cardiovascular stents. Deploying biodegradable materials to fabricate stents not only obviates a second surgical intervention for implant removal but also circumvents the long-term foreign body effect of permanent implants. However, these materials for stents suffer from an un-controlled degradation rate, acute toxic responses, and rapid structural failure presumably due to a non-uniform, fast corrosion process. Here we report that highly uniform, nanophasic degradation is achieved in a new Mg alloy with unique interstitial alloying composition as the nominal formula Mg–2.5Nd–0.2Zn–0.4Zr (wt%, hereafter, denoted as JDBM). This material exhibits highly homogeneous nanophasic biodegradation patterns as compared to other biodegradable metal alloy materials. Consequently it has significantly reduced degradation rate determined by electrochemical characterization. The in vitro cytotoxicity test using human vascular endothelial cells indicates excellent biocompatibility and potentially minimal toxic effect on arterial vessel walls. Finally, we fabricated a cardiovascular stent using JDBM and performed in vivo long-term assessment via implantation of this stent in an animal model. The results confirmed the reduced degradation rate in vivo, excellent tissue compatibility and long-term structural and mechanical durability. Thus, this new Mg-alloy with highly uniform nanophasic biodegradation represents a major breakthrough in the field and a promising material for manufacturing the next generation biodegradable vascular stents." @default.
• W2114824633 created "2016-06-24" @default.
• W2114824633 creator A5002129923 @default.
• W2114824633 creator A5003757832 @default.
• W2114824633 creator A5013529158 @default.
• W2114824633 creator A5043270834 @default.
• W2114824633 creator A5048267181 @default.
• W2114824633 creator A5052010000 @default.
• W2114824633 creator A5083093957 @default.
• W2114824633 creator A5083773499 @default.
• W2114824633 date "2013-01-01" @default.
• W2114824633 modified "2023-10-07" @default.
• W2114824633 title "Nanophasic biodegradation enhances the durability and biocompatibility of magnesium alloys for the next-generation vascular stents" @default.
• W2114824633 cites W1972757170 @default.
• W2114824633 cites W1989715462 @default.
• W2114824633 cites W1992174590 @default.
• W2114824633 cites W2015622869 @default.
• W2114824633 cites W2024530973 @default.
• W2114824633 cites W2032542005 @default.
• W2114824633 cites W2040235837 @default.
• W2114824633 cites W2045423781 @default.
• W2114824633 cites W2080109744 @default.
• W2114824633 cites W2086192467 @default.
• W2114824633 cites W2087881385 @default.
• W2114824633 cites W2089237206 @default.
• W2114824633 cites W2094088146 @default.
• W2114824633 cites W2094561136 @default.
• W2114824633 cites W2121469024 @default.
• W2114824633 cites W2144903822 @default.
• W2114824633 cites W2151351059 @default.
• W2114824633 cites W2166882028 @default.
• W2114824633 cites W4237344896 @default.
• W2114824633 doi "https://doi.org/10.1039/c3nr02912c" @default.
• W2114824633 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23989064" @default.
• W2114824633 hasPublicationYear "2013" @default.
• W2114824633 type Work @default.
• W2114824633 sameAs 2114824633 @default.
• W2114824633 citedByCount "89" @default.
• W2114824633 countsByYear W21148246332013 @default.
• W2114824633 countsByYear W21148246332014 @default.
• W2114824633 countsByYear W21148246332015 @default.
• W2114824633 countsByYear W21148246332016 @default.
• W2114824633 countsByYear W21148246332017 @default.
• W2114824633 countsByYear W21148246332018 @default.
• W2114824633 countsByYear W21148246332019 @default.
• W2114824633 countsByYear W21148246332020 @default.
• W2114824633 countsByYear W21148246332021 @default.
• W2114824633 countsByYear W21148246332022 @default.
• W2114824633 countsByYear W21148246332023 @default.
• W2114824633 crossrefType "journal-article" @default.
• W2114824633 hasAuthorship W2114824633A5002129923 @default.
• W2114824633 hasAuthorship W2114824633A5003757832 @default.
• W2114824633 hasAuthorship W2114824633A5013529158 @default.
• W2114824633 hasAuthorship W2114824633A5043270834 @default.
• W2114824633 hasAuthorship W2114824633A5048267181 @default.
• W2114824633 hasAuthorship W2114824633A5052010000 @default.
• W2114824633 hasAuthorship W2114824633A5083093957 @default.
• W2114824633 hasAuthorship W2114824633A5083773499 @default.
• W2114824633 hasConcept C104304963 @default.
• W2114824633 hasConcept C136229726 @default.
• W2114824633 hasConcept C141071460 @default.
• W2114824633 hasConcept C150903083 @default.
• W2114824633 hasConcept C157021035 @default.
• W2114824633 hasConcept C159985019 @default.
• W2114824633 hasConcept C171250308 @default.
• W2114824633 hasConcept C178790620 @default.
• W2114824633 hasConcept C185592680 @default.
• W2114824633 hasConcept C191897082 @default.
• W2114824633 hasConcept C192562407 @default.
• W2114824633 hasConcept C207001950 @default.
• W2114824633 hasConcept C2777230088 @default.
• W2114824633 hasConcept C2778583881 @default.
• W2114824633 hasConcept C2779679103 @default.
• W2114824633 hasConcept C2780026712 @default.
• W2114824633 hasConcept C2781411149 @default.
• W2114824633 hasConcept C41008148 @default.
• W2114824633 hasConcept C71924100 @default.
• W2114824633 hasConcept C76155785 @default.
• W2114824633 hasConcept C86803240 @default.
• W2114824633 hasConceptScore W2114824633C104304963 @default.
• W2114824633 hasConceptScore W2114824633C136229726 @default.
• W2114824633 hasConceptScore W2114824633C141071460 @default.
• W2114824633 hasConceptScore W2114824633C150903083 @default.
• W2114824633 hasConceptScore W2114824633C157021035 @default.
• W2114824633 hasConceptScore W2114824633C159985019 @default.
• W2114824633 hasConceptScore W2114824633C171250308 @default.
• W2114824633 hasConceptScore W2114824633C178790620 @default.
• W2114824633 hasConceptScore W2114824633C185592680 @default.
• W2114824633 hasConceptScore W2114824633C191897082 @default.
• W2114824633 hasConceptScore W2114824633C192562407 @default.
• W2114824633 hasConceptScore W2114824633C207001950 @default.
• W2114824633 hasConceptScore W2114824633C2777230088 @default.
• W2114824633 hasConceptScore W2114824633C2778583881 @default.
• W2114824633 hasConceptScore W2114824633C2779679103 @default.
• W2114824633 hasConceptScore W2114824633C2780026712 @default.
• W2114824633 hasConceptScore W2114824633C2781411149 @default.
• W2114824633 hasConceptScore W2114824633C41008148 @default.
• W2114824633 hasConceptScore W2114824633C71924100 @default.

• next