FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114866570> ?p ?o ?g. }

• W2114866570 endingPage "6367" @default.
• W2114866570 startingPage "6360" @default.
• W2114866570 abstract "ABSTRACT The decapeptide killer peptide (KP) derived from the sequence of a single-chain, anti-idiotypic antibody acting as a functional internal image of a microbicidal, broad-spectrum yeast killer toxin (KT) was shown to exert a strong microbicidal activity against human pathogens. With the aim to exploit this peptide to confer resistance to plant pathogens, we assayed its antimicrobial activity against a broad spectrum of phytopathogenic bacteria and fungi. Synthetic KP exhibited antimicrobial activity in vitro towards Pseudomonas syringae , Erwinia carotovora , Botrytis cinerea , and Fusarium oxysporum . KP was also expressed in plants by using a Potato virus X (PVX)-derived vector as a fusion to the viral coat protein, yielding chimeric virus particles (CVPs) displaying the heterologous peptide. Purified CVPs showed enhanced antimicrobial activity against the above-mentioned plant pathogens and human pathogens such as Staphylococcus aureus and Candida albicans . Moreover, in vivo assays designed to challenge KP-expressing plants (as CVPs) with Pseudomonas syringae pv. tabaci showed enhanced resistance to bacterial attack. The results indicate that the PVX-based display system is a high-yield, rapid, and efficient method to produce and evaluate antimicrobial peptides in plants, representing a milestone for the large-scale production of high-added-value peptides through molecular farming. Moreover, KP is a promising molecule to be stably engineered in plants to confer broad-spectrum resistance to phytopathogens." @default.
• W2114866570 created "2016-06-24" @default.
• W2114866570 creator A5007413456 @default.
• W2114866570 creator A5009136557 @default.
• W2114866570 creator A5010634757 @default.
• W2114866570 creator A5013664452 @default.
• W2114866570 creator A5032029561 @default.
• W2114866570 creator A5045561296 @default.
• W2114866570 creator A5066577751 @default.
• W2114866570 date "2005-10-01" @default.
• W2114866570 modified "2023-10-01" @default.
• W2114866570 title "Production of an Engineered Killer Peptide in<i>Nicotiana benthamiana</i>by Using a<i>Potato virus X</i>Expression System" @default.
• W2114866570 cites W1484232481 @default.
• W2114866570 cites W1512422408 @default.
• W2114866570 cites W1514282028 @default.
• W2114866570 cites W1527748238 @default.
• W2114866570 cites W1565479825 @default.
• W2114866570 cites W1566827176 @default.
• W2114866570 cites W1574072708 @default.
• W2114866570 cites W1578714703 @default.
• W2114866570 cites W1599630939 @default.
• W2114866570 cites W1968157068 @default.
• W2114866570 cites W1972006278 @default.
• W2114866570 cites W1972449754 @default.
• W2114866570 cites W1981646808 @default.
• W2114866570 cites W1986360179 @default.
• W2114866570 cites W1993792452 @default.
• W2114866570 cites W1997575569 @default.
• W2114866570 cites W2001825353 @default.
• W2114866570 cites W2002592834 @default.
• W2114866570 cites W2005220928 @default.
• W2114866570 cites W2011733259 @default.
• W2114866570 cites W2014319406 @default.
• W2114866570 cites W2014321075 @default.
• W2114866570 cites W2015538538 @default.
• W2114866570 cites W2018822159 @default.
• W2114866570 cites W2021367598 @default.
• W2114866570 cites W2028323881 @default.
• W2114866570 cites W2029927999 @default.
• W2114866570 cites W2033802329 @default.
• W2114866570 cites W2034911101 @default.
• W2114866570 cites W2046182783 @default.
• W2114866570 cites W2061816975 @default.
• W2114866570 cites W2062230922 @default.
• W2114866570 cites W2064222825 @default.
• W2114866570 cites W2069852531 @default.
• W2114866570 cites W2079578919 @default.
• W2114866570 cites W2091276023 @default.
• W2114866570 cites W2092147320 @default.
• W2114866570 cites W2096415553 @default.
• W2114866570 cites W2110894948 @default.
• W2114866570 cites W2115995288 @default.
• W2114866570 cites W2120706631 @default.
• W2114866570 cites W2124639420 @default.
• W2114866570 cites W2142605443 @default.
• W2114866570 cites W2143658252 @default.
• W2114866570 cites W2157122286 @default.
• W2114866570 cites W2157465146 @default.
• W2114866570 cites W2160665697 @default.
• W2114866570 cites W2164527203 @default.
• W2114866570 cites W2412600577 @default.
• W2114866570 cites W260664763 @default.
• W2114866570 doi "https://doi.org/10.1128/aem.71.10.6360-6367.2005" @default.
• W2114866570 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1265961" @default.
• W2114866570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16204558" @default.
• W2114866570 hasPublicationYear "2005" @default.
• W2114866570 type Work @default.
• W2114866570 sameAs 2114866570 @default.
• W2114866570 citedByCount "40" @default.
• W2114866570 countsByYear W21148665702012 @default.
• W2114866570 countsByYear W21148665702013 @default.
• W2114866570 countsByYear W21148665702014 @default.
• W2114866570 countsByYear W21148665702015 @default.
• W2114866570 countsByYear W21148665702017 @default.
• W2114866570 countsByYear W21148665702018 @default.
• W2114866570 countsByYear W21148665702019 @default.
• W2114866570 crossrefType "journal-article" @default.
• W2114866570 hasAuthorship W2114866570A5007413456 @default.
• W2114866570 hasAuthorship W2114866570A5009136557 @default.
• W2114866570 hasAuthorship W2114866570A5010634757 @default.
• W2114866570 hasAuthorship W2114866570A5013664452 @default.
• W2114866570 hasAuthorship W2114866570A5032029561 @default.
• W2114866570 hasAuthorship W2114866570A5045561296 @default.
• W2114866570 hasAuthorship W2114866570A5066577751 @default.
• W2114866570 hasBestOaLocation W21148665702 @default.
• W2114866570 hasConcept C109110057 @default.
• W2114866570 hasConcept C159047783 @default.
• W2114866570 hasConcept C2522874641 @default.
• W2114866570 hasConcept C2775867217 @default.
• W2114866570 hasConcept C2776460866 @default.
• W2114866570 hasConcept C2777642389 @default.
• W2114866570 hasConcept C2780381237 @default.
• W2114866570 hasConcept C2780562374 @default.
• W2114866570 hasConcept C4937899 @default.
• W2114866570 hasConcept C540938839 @default.
• W2114866570 hasConcept C59822182 @default.
• W2114866570 hasConcept C86803240 @default.
• W2114866570 hasConcept C89423630 @default.

• next