FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114892913> ?p ?o ?g. }

• W2114892913 abstract "Members of the TGF-beta/BMP family of growth factors induce odontoblast differentiation and reparative dentin synthesis, and their use has been proposed to stimulate pulp healing during dental therapeutics in human. However, factors that modulate TGF-beta and/or BMP signalling during odontoblast differentiation and physiology remain largely unknown. To identify them, we compared expression profiles of TGF-beta/BMP-related genes in pulp fibroblast- and odontoblast-like cells cultured from human dental pulp explants using cDNA gene arrays. We evidenced that the gene encoding ecotropic viral integration site-1 (EVI1), a transcription factor that inhibits TGF-beta/BMP signalling, was under-expressed in odontoblast-like cells. This result was verified by real-time PCR and, at the protein level, by immunohistochemistry. In vivo, real-time PCR analysis revealed that EVI1 was expressed in the dental pulp, at a level similar to brain, but lower than in lung, kidney or trachea. The protein was localized in dental pulp samples in pulp core and subodontoblast cells. Staining intensity progressively decreased from the radicular to the coronal pulp where EVI1 staining was almost undetectable in odontoblasts. Our data suggest that fine regulation of the EVI1 level in the human dental pulp might be important in the TGF-beta/BMP-induced modulation of dental pulp cell kinetics and/or odontoblast differentiation." @default.
• W2114892913 created "2016-06-24" @default.
• W2114892913 creator A5004205138 @default.
• W2114892913 creator A5008631605 @default.
• W2114892913 creator A5017339980 @default.
• W2114892913 creator A5044741063 @default.
• W2114892913 creator A5046597795 @default.
• W2114892913 creator A5052971048 @default.
• W2114892913 creator A5058493866 @default.
• W2114892913 creator A5072203592 @default.
• W2114892913 creator A5074554675 @default.
• W2114892913 date "2007-08-01" @default.
• W2114892913 modified "2023-10-14" @default.
• W2114892913 title "Expression of the TGF-β/BMP inhibitor EVI1 in human dental pulp cells" @default.
• W2114892913 cites W1532921008 @default.
• W2114892913 cites W1617041404 @default.
• W2114892913 cites W1970743974 @default.
• W2114892913 cites W1976260078 @default.
• W2114892913 cites W1978146894 @default.
• W2114892913 cites W1979518793 @default.
• W2114892913 cites W1983291068 @default.
• W2114892913 cites W1994798295 @default.
• W2114892913 cites W2006349218 @default.
• W2114892913 cites W2012490303 @default.
• W2114892913 cites W2017528608 @default.
• W2114892913 cites W2023904245 @default.
• W2114892913 cites W2025266673 @default.
• W2114892913 cites W2032750910 @default.
• W2114892913 cites W2035653659 @default.
• W2114892913 cites W2036819945 @default.
• W2114892913 cites W2044251825 @default.
• W2114892913 cites W2047632128 @default.
• W2114892913 cites W2059797981 @default.
• W2114892913 cites W2060904166 @default.
• W2114892913 cites W2063014741 @default.
• W2114892913 cites W2063364980 @default.
• W2114892913 cites W2066914839 @default.
• W2114892913 cites W2071831776 @default.
• W2114892913 cites W2074624875 @default.
• W2114892913 cites W2080002619 @default.
• W2114892913 cites W2080915541 @default.
• W2114892913 cites W2093618481 @default.
• W2114892913 cites W2098996143 @default.
• W2114892913 cites W2103031848 @default.
• W2114892913 cites W2110149781 @default.
• W2114892913 cites W2121039238 @default.
• W2114892913 cites W2137565844 @default.
• W2114892913 cites W2141191556 @default.
• W2114892913 cites W2143355129 @default.
• W2114892913 cites W2154568166 @default.
• W2114892913 cites W2183300678 @default.
• W2114892913 cites W2337472889 @default.
• W2114892913 doi "https://doi.org/10.1016/j.archoralbio.2007.01.012" @default.
• W2114892913 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17328861" @default.
• W2114892913 hasPublicationYear "2007" @default.
• W2114892913 type Work @default.
• W2114892913 sameAs 2114892913 @default.
• W2114892913 citedByCount "10" @default.
• W2114892913 countsByYear W21148929132012 @default.
• W2114892913 countsByYear W21148929132015 @default.
• W2114892913 countsByYear W21148929132019 @default.
• W2114892913 countsByYear W21148929132020 @default.
• W2114892913 crossrefType "journal-article" @default.
• W2114892913 hasAuthorship W2114892913A5004205138 @default.
• W2114892913 hasAuthorship W2114892913A5008631605 @default.
• W2114892913 hasAuthorship W2114892913A5017339980 @default.
• W2114892913 hasAuthorship W2114892913A5044741063 @default.
• W2114892913 hasAuthorship W2114892913A5046597795 @default.
• W2114892913 hasAuthorship W2114892913A5052971048 @default.
• W2114892913 hasAuthorship W2114892913A5058493866 @default.
• W2114892913 hasAuthorship W2114892913A5072203592 @default.
• W2114892913 hasAuthorship W2114892913A5074554675 @default.
• W2114892913 hasConcept C104317684 @default.
• W2114892913 hasConcept C118131993 @default.
• W2114892913 hasConcept C125349252 @default.
• W2114892913 hasConcept C153911025 @default.
• W2114892913 hasConcept C185592680 @default.
• W2114892913 hasConcept C188442228 @default.
• W2114892913 hasConcept C199343813 @default.
• W2114892913 hasConcept C202751555 @default.
• W2114892913 hasConcept C2520015 @default.
• W2114892913 hasConcept C2777400515 @default.
• W2114892913 hasConcept C2778229498 @default.
• W2114892913 hasConcept C2780381497 @default.
• W2114892913 hasConcept C28328180 @default.
• W2114892913 hasConcept C30352789 @default.
• W2114892913 hasConcept C31507581 @default.
• W2114892913 hasConcept C55493867 @default.
• W2114892913 hasConcept C71924100 @default.
• W2114892913 hasConcept C86803240 @default.
• W2114892913 hasConcept C95444343 @default.
• W2114892913 hasConceptScore W2114892913C104317684 @default.
• W2114892913 hasConceptScore W2114892913C118131993 @default.
• W2114892913 hasConceptScore W2114892913C125349252 @default.
• W2114892913 hasConceptScore W2114892913C153911025 @default.
• W2114892913 hasConceptScore W2114892913C185592680 @default.
• W2114892913 hasConceptScore W2114892913C188442228 @default.
• W2114892913 hasConceptScore W2114892913C199343813 @default.
• W2114892913 hasConceptScore W2114892913C202751555 @default.
• W2114892913 hasConceptScore W2114892913C2520015 @default.

• next