Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114911345> ?p ?o ?g. }
- W2114911345 endingPage "57" @default.
- W2114911345 startingPage "449" @default.
- W2114911345 abstract "To provide family physicians with practical ways of managing depressed patients responding insufficiently to initial antidepressant treatment.A search of MEDLINE and relevant bibliographies showed most studies could be categorized as level III evidence. Few well controlled studies (eg, level I evidence) specify treatment of next choice in rigorously defined treatment-refractory depression (TRD).Failure to achieve and sustain full symptom remission affects relatively few treated depressed patients. Most chronically depressed people are not absolutely resistant but are relatively resistant to treatment; they fail to achieve the goals of treatment because of improper diagnosis or insufficient treatment application. The literature on TRD has largely focused on medication strategies; fewer studies investigated psychosocial approaches. The best established augmentation strategies are lithium salts and triidothyronine (T3). Combination antidepressants have become clinical psychiatrists' preferred treatment, despite limited evidence. Electroconvulsive therapy (ECT) remains a feasible option for TRD, but response rates are poor among people with TRD. High relapse rates after ECT remain a serious and common clinical dilemma.Family physicians should familiarize themselves with some new strategies to modify inadequate response to initial antidepressant treatment." @default.
- W2114911345 created "2016-06-24" @default.
- W2114911345 creator A5000590729 @default.
- W2114911345 creator A5044819148 @default.
- W2114911345 creator A5068850044 @default.
- W2114911345 creator A5071192003 @default.
- W2114911345 date "2003-04-01" @default.
- W2114911345 modified "2023-09-26" @default.
- W2114911345 title "What to do if an initial antidepressant fails?" @default.
- W2114911345 cites W1515279996 @default.
- W2114911345 cites W1519800783 @default.
- W2114911345 cites W1578313693 @default.
- W2114911345 cites W1581257829 @default.
- W2114911345 cites W1599530923 @default.
- W2114911345 cites W1762787217 @default.
- W2114911345 cites W180218168 @default.
- W2114911345 cites W187528805 @default.
- W2114911345 cites W1944976733 @default.
- W2114911345 cites W1962821909 @default.
- W2114911345 cites W1984444217 @default.
- W2114911345 cites W1986842900 @default.
- W2114911345 cites W2003982930 @default.
- W2114911345 cites W2005066505 @default.
- W2114911345 cites W2009549897 @default.
- W2114911345 cites W2011709753 @default.
- W2114911345 cites W2014614851 @default.
- W2114911345 cites W2021675008 @default.
- W2114911345 cites W2027778520 @default.
- W2114911345 cites W2031799297 @default.
- W2114911345 cites W2035148491 @default.
- W2114911345 cites W2035353883 @default.
- W2114911345 cites W2043046773 @default.
- W2114911345 cites W2046970666 @default.
- W2114911345 cites W2051442680 @default.
- W2114911345 cites W2052785022 @default.
- W2114911345 cites W2063291862 @default.
- W2114911345 cites W2071696563 @default.
- W2114911345 cites W2071898382 @default.
- W2114911345 cites W2073585506 @default.
- W2114911345 cites W2080896438 @default.
- W2114911345 cites W2082857343 @default.
- W2114911345 cites W2085769789 @default.
- W2114911345 cites W2112334970 @default.
- W2114911345 cites W2112540509 @default.
- W2114911345 cites W2114693958 @default.
- W2114911345 cites W2116579677 @default.
- W2114911345 cites W2120180412 @default.
- W2114911345 cites W2121928096 @default.
- W2114911345 cites W2122681119 @default.
- W2114911345 cites W2126369654 @default.
- W2114911345 cites W2126668978 @default.
- W2114911345 cites W2143002682 @default.
- W2114911345 cites W2148560706 @default.
- W2114911345 cites W2155275341 @default.
- W2114911345 cites W2156139207 @default.
- W2114911345 cites W2167845443 @default.
- W2114911345 cites W2210637379 @default.
- W2114911345 cites W2227425106 @default.
- W2114911345 cites W2230907131 @default.
- W2114911345 cites W2321953674 @default.
- W2114911345 cites W2326556724 @default.
- W2114911345 cites W2327335541 @default.
- W2114911345 cites W2416036002 @default.
- W2114911345 cites W2467798782 @default.
- W2114911345 cites W2993399942 @default.
- W2114911345 cites W2994532047 @default.
- W2114911345 cites W59251613 @default.
- W2114911345 cites W73023600 @default.
- W2114911345 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2214210" @default.
- W2114911345 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12729241" @default.
- W2114911345 hasPublicationYear "2003" @default.
- W2114911345 type Work @default.
- W2114911345 sameAs 2114911345 @default.
- W2114911345 citedByCount "10" @default.
- W2114911345 countsByYear W21149113452013 @default.
- W2114911345 crossrefType "journal-article" @default.
- W2114911345 hasAuthorship W2114911345A5000590729 @default.
- W2114911345 hasAuthorship W2114911345A5044819148 @default.
- W2114911345 hasAuthorship W2114911345A5068850044 @default.
- W2114911345 hasAuthorship W2114911345A5071192003 @default.
- W2114911345 hasConcept C111472728 @default.
- W2114911345 hasConcept C118552586 @default.
- W2114911345 hasConcept C121332964 @default.
- W2114911345 hasConcept C138885662 @default.
- W2114911345 hasConcept C139719470 @default.
- W2114911345 hasConcept C142424586 @default.
- W2114911345 hasConcept C150966472 @default.
- W2114911345 hasConcept C162324750 @default.
- W2114911345 hasConcept C17744445 @default.
- W2114911345 hasConcept C177713679 @default.
- W2114911345 hasConcept C199539241 @default.
- W2114911345 hasConcept C2776412080 @default.
- W2114911345 hasConcept C2776867660 @default.
- W2114911345 hasConcept C2777330709 @default.
- W2114911345 hasConcept C2777342061 @default.
- W2114911345 hasConcept C2778496695 @default.
- W2114911345 hasConcept C2778541603 @default.
- W2114911345 hasConcept C2779177272 @default.