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• W2114918261 abstract "The great potential for medical applications of inorganic nanoparticles in living organisms is severely restricted by the concern that nanoparticles can harmfully interact with biological systems, such as lipid membranes or cell proteins. To enable an uptake of such nanoparticles by cells without harming their membranes, platinum nanoparticles were synthesized within cavities of hollow protein nanospheres (apoferritin). In vitro, the protein-platinum nanoparticles show good catalytic efficiency and long-term stability. Subsequently the particles were tested after ferritin-receptor-mediated incorporation in human intestinal Caco-2 cells. Upon externally induced stress, for example, with hydrogen peroxide, the oxygen species in the cells decreased and the viability of the cells increased." @default.
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• W2114918261 date "2009-12-17" @default.
• W2114918261 modified "2023-10-17" @default.
• W2114918261 title "Reducing Stress on Cells with Apoferritin-Encapsulated Platinum Nanoparticles" @default.
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• W2114918261 doi "https://doi.org/10.1021/nl903313r" @default.
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