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- W2114922134 endingPage "88" @default.
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- W2114922134 abstract "By means of atomistic molecular dynamics simulations, we study cholesterol-DPPC (dipalmitoyl phosphatidylcholine) bilayers of different composition, from pure DPPC bilayers to a 1:1 mixture of DPPC and cholesterol. The lateral pressure profiles through the bilayers are computed and separated into contributions from the different components. We find that the pressure inside the bilayer changes qualitatively for cholesterol concentrations of about 20% or higher. The pressure profile in the inside of the bilayer then turns from a rather flat shape into an alternating sequence of regions with large positive and negative lateral pressure. The changes in the lateral pressure profile are so characteristic that specific interaction between cholesterol and molecules such as membrane proteins mediated solely via the lateral pressure profile might become possible." @default.
- W2114922134 created "2016-06-24" @default.
- W2114922134 creator A5055158239 @default.
- W2114922134 date "2005-10-05" @default.
- W2114922134 modified "2023-10-13" @default.
- W2114922134 title "Lateral pressure profiles in cholesterol–DPPC bilayers" @default.
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- W2114922134 doi "https://doi.org/10.1007/s00249-005-0011-0" @default.
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