Matches in SemOpenAlex for { <https://semopenalex.org/work/W2114942012> ?p ?o ?g. }
- W2114942012 endingPage "1101" @default.
- W2114942012 startingPage "1096" @default.
- W2114942012 abstract "Little is known as to how hepatectomy is associated with the growth of hepatic tumours, which may reside in the remaining liver after curative resection for hepatocellular carcinoma. Using an intra-hepatic tumour implantation model in rats, the effects of hepatectomy on tumour growth in the remaining liver were investigated. On post-operative day 7, the tumour weight in the remaining liver following 30% hepatectomy was 0.321 ± 0.058 g (mean ± SD) which was significantly greater than that (0.245 ± 0.040 g) in sham operations (P < 0.05). However, the tumour weight (0.156 ± 0.067 g) in the remaining liver following 60% hepatectomy was significantly lower than that in sham animals (P < 0.005). The number of TdT-mediated dUTP nick-end labelling (TUNEL) positive tumour cells was significantly increased in 60% hepatectomy as compared with the sham and 30% hepatectomy group. The mRNA expression of TGF-β1, TNF-α and Fas in the tumour portion of 60% hepatectomy, was higher than that in 30% hepatectomy group. Plasma levels of TGF-β1 were inversely correlated with intra-hepatic tumour weights. These results suggest that major hepatic resection may lead to an increased induction of apoptosis for the remaining hepatic tumour. © 2000 Cancer Research Campaign" @default.
- W2114942012 created "2016-06-24" @default.
- W2114942012 creator A5003880330 @default.
- W2114942012 creator A5009661886 @default.
- W2114942012 creator A5055231348 @default.
- W2114942012 creator A5057378015 @default.
- W2114942012 creator A5074377492 @default.
- W2114942012 creator A5075811653 @default.
- W2114942012 date "2000-10-01" @default.
- W2114942012 modified "2023-10-14" @default.
- W2114942012 title "Major hepatic resection may suppress the growth of tumours remaining in the residual liver" @default.
- W2114942012 cites W1557164803 @default.
- W2114942012 cites W1558416075 @default.
- W2114942012 cites W1559658698 @default.
- W2114942012 cites W167223055 @default.
- W2114942012 cites W1841601429 @default.
- W2114942012 cites W1964337404 @default.
- W2114942012 cites W1982308850 @default.
- W2114942012 cites W1984973295 @default.
- W2114942012 cites W1998649957 @default.
- W2114942012 cites W2006217850 @default.
- W2114942012 cites W2012707575 @default.
- W2114942012 cites W2013559803 @default.
- W2114942012 cites W2013592953 @default.
- W2114942012 cites W2017377497 @default.
- W2114942012 cites W2019029050 @default.
- W2114942012 cites W2024157438 @default.
- W2114942012 cites W2027379399 @default.
- W2114942012 cites W2032344536 @default.
- W2114942012 cites W2032929812 @default.
- W2114942012 cites W2035911481 @default.
- W2114942012 cites W2045796964 @default.
- W2114942012 cites W2048653029 @default.
- W2114942012 cites W2054088593 @default.
- W2114942012 cites W2073894669 @default.
- W2114942012 cites W2075809552 @default.
- W2114942012 cites W2084609653 @default.
- W2114942012 cites W2102854687 @default.
- W2114942012 cites W2134691685 @default.
- W2114942012 cites W2138302361 @default.
- W2114942012 cites W2147599491 @default.
- W2114942012 cites W2283844404 @default.
- W2114942012 cites W2340798637 @default.
- W2114942012 cites W4302561293 @default.
- W2114942012 doi "https://doi.org/10.1054/bjoc.2000.1379" @default.
- W2114942012 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2363560" @default.
- W2114942012 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10993659" @default.
- W2114942012 hasPublicationYear "2000" @default.
- W2114942012 type Work @default.
- W2114942012 sameAs 2114942012 @default.
- W2114942012 citedByCount "17" @default.
- W2114942012 countsByYear W21149420122012 @default.
- W2114942012 countsByYear W21149420122014 @default.
- W2114942012 countsByYear W21149420122016 @default.
- W2114942012 countsByYear W21149420122017 @default.
- W2114942012 countsByYear W21149420122020 @default.
- W2114942012 crossrefType "journal-article" @default.
- W2114942012 hasAuthorship W2114942012A5003880330 @default.
- W2114942012 hasAuthorship W2114942012A5009661886 @default.
- W2114942012 hasAuthorship W2114942012A5055231348 @default.
- W2114942012 hasAuthorship W2114942012A5057378015 @default.
- W2114942012 hasAuthorship W2114942012A5074377492 @default.
- W2114942012 hasAuthorship W2114942012A5075811653 @default.
- W2114942012 hasBestOaLocation W21149420121 @default.
- W2114942012 hasConcept C126322002 @default.
- W2114942012 hasConcept C134018914 @default.
- W2114942012 hasConcept C141071460 @default.
- W2114942012 hasConcept C142724271 @default.
- W2114942012 hasConcept C159110652 @default.
- W2114942012 hasConcept C190283241 @default.
- W2114942012 hasConcept C196795494 @default.
- W2114942012 hasConcept C204232928 @default.
- W2114942012 hasConcept C2776231280 @default.
- W2114942012 hasConcept C2776909242 @default.
- W2114942012 hasConcept C2777546739 @default.
- W2114942012 hasConcept C2778019345 @default.
- W2114942012 hasConcept C55493867 @default.
- W2114942012 hasConcept C71924100 @default.
- W2114942012 hasConcept C86803240 @default.
- W2114942012 hasConcept C90924648 @default.
- W2114942012 hasConceptScore W2114942012C126322002 @default.
- W2114942012 hasConceptScore W2114942012C134018914 @default.
- W2114942012 hasConceptScore W2114942012C141071460 @default.
- W2114942012 hasConceptScore W2114942012C142724271 @default.
- W2114942012 hasConceptScore W2114942012C159110652 @default.
- W2114942012 hasConceptScore W2114942012C190283241 @default.
- W2114942012 hasConceptScore W2114942012C196795494 @default.
- W2114942012 hasConceptScore W2114942012C204232928 @default.
- W2114942012 hasConceptScore W2114942012C2776231280 @default.
- W2114942012 hasConceptScore W2114942012C2776909242 @default.
- W2114942012 hasConceptScore W2114942012C2777546739 @default.
- W2114942012 hasConceptScore W2114942012C2778019345 @default.
- W2114942012 hasConceptScore W2114942012C55493867 @default.
- W2114942012 hasConceptScore W2114942012C71924100 @default.
- W2114942012 hasConceptScore W2114942012C86803240 @default.
- W2114942012 hasConceptScore W2114942012C90924648 @default.
- W2114942012 hasIssue "8" @default.
- W2114942012 hasLocation W21149420121 @default.