Matches in SemOpenAlex for { <https://semopenalex.org/work/W2115088277> ?p ?o ?g. }
- W2115088277 endingPage "688" @default.
- W2115088277 startingPage "683" @default.
- W2115088277 abstract "Magnetic resonance spectroscopy (MRS) is a unique non-invasive method for detecting cardiac metabolic changes. However, MRS in cardiac diagnosis is limited due to insensitivity and low efficiency. Taurine (Tau) is the most abundant free amino acid in the myocardium. We hypothesized that Tau levels may indicate myocardial ischemia and early infarction. Sprague-Dawley rats were divided into seven groups according to different time points during the course of myocardial ischemia, which was induced by left anterior descending coronary artery ligation. Infarcted myocardial tissue was obtained for high-resolution magic angle spinning (1)H nuclear magnetic resonance (NMR) analysis. Results were validated via high-performance liquid chromatography. The Tau levels in the ischemic myocardial tissue were reduced significantly within 5 min compared with those in the control group (relative ratio from 20.27±6.48 to 8.81±0.04, P<0.05) and were maintained for 6 h post-ischemia. Tau levels declined more markedly (56.5%) than creatine levels (48.5%) at 5 min after ligation. This suggests that Tau may have potential as an indicator in the early detection of myocardial ischemia by (1)H MRS." @default.
- W2115088277 created "2016-06-24" @default.
- W2115088277 creator A5000483207 @default.
- W2115088277 creator A5001624794 @default.
- W2115088277 creator A5010776860 @default.
- W2115088277 creator A5015649009 @default.
- W2115088277 creator A5022946499 @default.
- W2115088277 creator A5040443777 @default.
- W2115088277 creator A5040885802 @default.
- W2115088277 creator A5043490198 @default.
- W2115088277 creator A5062093731 @default.
- W2115088277 creator A5078164215 @default.
- W2115088277 creator A5089244317 @default.
- W2115088277 date "2012-12-13" @default.
- W2115088277 modified "2023-10-05" @default.
- W2115088277 title "Taurine detected using high-resolution magic angle spinning 1H nuclear magnetic resonance: A potential indicator of early myocardial infarction" @default.
- W2115088277 cites W1528671715 @default.
- W2115088277 cites W1968286219 @default.
- W2115088277 cites W1968963326 @default.
- W2115088277 cites W1969177333 @default.
- W2115088277 cites W1969899562 @default.
- W2115088277 cites W1972873791 @default.
- W2115088277 cites W1986853673 @default.
- W2115088277 cites W1990494423 @default.
- W2115088277 cites W1995527759 @default.
- W2115088277 cites W1997400572 @default.
- W2115088277 cites W2000358503 @default.
- W2115088277 cites W2000941400 @default.
- W2115088277 cites W2003409824 @default.
- W2115088277 cites W2004616733 @default.
- W2115088277 cites W2016431737 @default.
- W2115088277 cites W2023036252 @default.
- W2115088277 cites W2026960877 @default.
- W2115088277 cites W2034344770 @default.
- W2115088277 cites W2036373055 @default.
- W2115088277 cites W2040618183 @default.
- W2115088277 cites W2061572691 @default.
- W2115088277 cites W2063571777 @default.
- W2115088277 cites W2064617184 @default.
- W2115088277 cites W2081084195 @default.
- W2115088277 cites W2083123206 @default.
- W2115088277 cites W2092912434 @default.
- W2115088277 cites W2093195469 @default.
- W2115088277 cites W2102622616 @default.
- W2115088277 cites W2117254307 @default.
- W2115088277 cites W2119117013 @default.
- W2115088277 cites W2124132924 @default.
- W2115088277 cites W2134965181 @default.
- W2115088277 cites W2145539290 @default.
- W2115088277 cites W2149498798 @default.
- W2115088277 cites W2171628639 @default.
- W2115088277 cites W2172041803 @default.
- W2115088277 cites W2176786484 @default.
- W2115088277 cites W2331933347 @default.
- W2115088277 cites W2404920737 @default.
- W2115088277 cites W2491061016 @default.
- W2115088277 cites W3148970527 @default.
- W2115088277 doi "https://doi.org/10.3892/etm.2012.857" @default.
- W2115088277 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3570233" @default.
- W2115088277 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23408155" @default.
- W2115088277 hasPublicationYear "2012" @default.
- W2115088277 type Work @default.
- W2115088277 sameAs 2115088277 @default.
- W2115088277 citedByCount "3" @default.
- W2115088277 countsByYear W21150882772015 @default.
- W2115088277 crossrefType "journal-article" @default.
- W2115088277 hasAuthorship W2115088277A5000483207 @default.
- W2115088277 hasAuthorship W2115088277A5001624794 @default.
- W2115088277 hasAuthorship W2115088277A5010776860 @default.
- W2115088277 hasAuthorship W2115088277A5015649009 @default.
- W2115088277 hasAuthorship W2115088277A5022946499 @default.
- W2115088277 hasAuthorship W2115088277A5040443777 @default.
- W2115088277 hasAuthorship W2115088277A5040885802 @default.
- W2115088277 hasAuthorship W2115088277A5043490198 @default.
- W2115088277 hasAuthorship W2115088277A5062093731 @default.
- W2115088277 hasAuthorship W2115088277A5078164215 @default.
- W2115088277 hasAuthorship W2115088277A5089244317 @default.
- W2115088277 hasBestOaLocation W21150882771 @default.
- W2115088277 hasConcept C121332964 @default.
- W2115088277 hasConcept C126322002 @default.
- W2115088277 hasConcept C126838900 @default.
- W2115088277 hasConcept C143409427 @default.
- W2115088277 hasConcept C164705383 @default.
- W2115088277 hasConcept C179437574 @default.
- W2115088277 hasConcept C185592680 @default.
- W2115088277 hasConcept C2776820930 @default.
- W2115088277 hasConcept C2777798775 @default.
- W2115088277 hasConcept C2779701627 @default.
- W2115088277 hasConcept C2779896295 @default.
- W2115088277 hasConcept C46141821 @default.
- W2115088277 hasConcept C500558357 @default.
- W2115088277 hasConcept C515207424 @default.
- W2115088277 hasConcept C541997718 @default.
- W2115088277 hasConcept C55493867 @default.
- W2115088277 hasConcept C66974803 @default.
- W2115088277 hasConcept C71924100 @default.
- W2115088277 hasConcept C84935128 @default.
- W2115088277 hasConceptScore W2115088277C121332964 @default.