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- W2115104005 abstract "Although rare, night terrors are difficult to treat and a major management problem, especially when accompanied by sleepwalking or other automatic behaviours. Severe injury (sometimes death) during the period of confusion following the rise from bed has been reported, 1 Schenck CH Mahowald MW Long-term nightly benzodiazepine treatment of injurious parasomnias and other disorders of disrupted nocturnal sleep in 170 adults. Am J Med. 1996; 100: 333-337 Summary Full Text PDF PubMed Scopus (242) Google Scholar and more frequent attacks lead to serious disruption of sleep, which may impair subsequent daytime functioning and result in psychiatric comorbidity. Night terrors can thus cause severe disability, and effective therapy would be of benefit to patients and their families. There have been reports of treatment with benzodiazepines, 1 Schenck CH Mahowald MW Long-term nightly benzodiazepine treatment of injurious parasomnias and other disorders of disrupted nocturnal sleep in 170 adults. Am J Med. 1996; 100: 333-337 Summary Full Text PDF PubMed Scopus (242) Google Scholar imipramine, 2 Cooper AJ Treatment of co-existent night terrors with imipramine. J Clin Psychiatry. 1987; 48: 209-210 PubMed Google Scholar and long-term psychotherapy, 3 Kales JD Cadieux RJ Soldatos CR Kales A Psychotherapy with night-terror patients. Psychother. 1982; 36: 399-407 Google Scholar but only benzodiazepines have shown any notable success. Selective serotonin reuptake inhibitors (SSRIs) have antipanic actions and there is some overlap in symptoms of nocturnal panic attacks and night terrors. We report a series of six patients with night terrors, referred for drug treatment because of distressing or dangerous accompanying behaviours, or sleep disruption. All six patients were assessed clinically and by home polysomnography (medilog). All responded to treatment with the SSRI paroxetine (table). TablePatient characteristics and response to treatment Patient Age (yr, at onset) Attack frequency Paroxetine dose (mg) Change in attack frequency 1 46 (14) 2–3/night 40 Abolition, no recurrence on stopping treatment 2 31 (15) 2–3/week 20 Reduction, recurrence on stopping treatment 3 30 (6) 4–5/week 20 Abolition, recurrence on stopping treatment 4 24 (13) 1/night 20 Abolition 5 31 (5) 2–3/week 20 Reduction, attacks on drug- free days when on alternate day dosage 6 45 (··) 1–2/night 20 Reduction Open table in a new tab" @default.
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- W2115104005 date "1997-07-01" @default.
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- W2115104005 title "Adult night terrors and paroxetine" @default.
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- W2115104005 doi "https://doi.org/10.1016/s0140-6736(05)62351-3" @default.
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