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• W2115273387 abstract "Blindness is an uncommon but devastating complication of tuberculosis meningitis. The main causes are chronically raised intracranial pressure (hydrocephalus and/or tuberculomas) or direct involvement of the optic chiasm or optic nerves by the basal arachnoiditis (inflammation and/or compression). Antituberculosis therapy combined with corticosteroids and control of intracranial pressure constitutes the mainstay of therapy for tuberculous meningitis. Despite these treatment measures, some patients develop blindness, mainly as a result of progressive optochiasmatic arachnoiditis. This led us to explore the role of adjuvant thalidomide therapy, and we describe the dramatic recovery of vision in 4 consecutive cases. Clinical recovery was accompanied by marked radiological improvement on magnetic resonance imaging (MRI) of the brain." @default.
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• W2115273387 date "2010-06-02" @default.
• W2115273387 modified "2023-09-23" @default.
• W2115273387 title "Tuberculous Meningitis-Related Optic Neuritis: Recovery of Vision With Thalidomide in 4 Consecutive Cases" @default.
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• W2115273387 doi "https://doi.org/10.1177/0883073809350507" @default.
• W2115273387 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20519667" @default.
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