Matches in SemOpenAlex for { <https://semopenalex.org/work/W2115348517> ?p ?o ?g. }
- W2115348517 endingPage "785" @default.
- W2115348517 startingPage "776" @default.
- W2115348517 abstract "Mutations in the zinc finger transcription factor ZIC3 are associated with human left-right patterning abnormalities (X-linked heterotaxy, HTX1, MIM 306955), and mice null for Zic3 show a similar phenotype. However, the developmental function of Zic3 is largely unknown and its expression in early embryonic development suggests a role prior to organ formation. The current study of Zic3 null mice identifies a novel function for Zic3 in the gastrula-stage embryo. Analysis of Zic3 function at early embryonic stages shows that it ensures the fidelity of embryonic patterning, including patterning of the anterior visceral endoderm, the initiation of gastrulation, and positioning of the primitive streak. At later stages, deficiency of Zic3 results in abnormal mesoderm allocation. These results indicate a requirement for Zic3 during early embryogenesis prior to cardiac and visceral organ patterning. Developmental Dynamics 235:776–785, 2006. © 2006 Wiley-Liss, Inc." @default.
- W2115348517 created "2016-06-24" @default.
- W2115348517 creator A5020642145 @default.
- W2115348517 creator A5047263678 @default.
- W2115348517 creator A5066687791 @default.
- W2115348517 date "2006-03-01" @default.
- W2115348517 modified "2023-10-09" @default.
- W2115348517 title "Zic3 is critical for early embryonic patterning during gastrulation" @default.
- W2115348517 cites W1533376056 @default.
- W2115348517 cites W1680418198 @default.
- W2115348517 cites W1922106993 @default.
- W2115348517 cites W1922337323 @default.
- W2115348517 cites W1959009706 @default.
- W2115348517 cites W1961367983 @default.
- W2115348517 cites W1968530627 @default.
- W2115348517 cites W1969923021 @default.
- W2115348517 cites W1970845471 @default.
- W2115348517 cites W1977376400 @default.
- W2115348517 cites W1979062316 @default.
- W2115348517 cites W1979717361 @default.
- W2115348517 cites W1979981202 @default.
- W2115348517 cites W1985360296 @default.
- W2115348517 cites W1988173672 @default.
- W2115348517 cites W2006937113 @default.
- W2115348517 cites W2008777486 @default.
- W2115348517 cites W2009872695 @default.
- W2115348517 cites W2010856041 @default.
- W2115348517 cites W2023116564 @default.
- W2115348517 cites W2039248606 @default.
- W2115348517 cites W2043188635 @default.
- W2115348517 cites W2054267083 @default.
- W2115348517 cites W2056872760 @default.
- W2115348517 cites W2057375692 @default.
- W2115348517 cites W2067924517 @default.
- W2115348517 cites W2069693786 @default.
- W2115348517 cites W2071255863 @default.
- W2115348517 cites W2073264990 @default.
- W2115348517 cites W2075347688 @default.
- W2115348517 cites W2077439507 @default.
- W2115348517 cites W2082993601 @default.
- W2115348517 cites W2092088384 @default.
- W2115348517 cites W2094145003 @default.
- W2115348517 cites W2103412450 @default.
- W2115348517 cites W2107943858 @default.
- W2115348517 cites W2120347846 @default.
- W2115348517 cites W2120410199 @default.
- W2115348517 cites W2127522049 @default.
- W2115348517 cites W2132069716 @default.
- W2115348517 cites W2132584224 @default.
- W2115348517 cites W2142951125 @default.
- W2115348517 cites W2147350988 @default.
- W2115348517 cites W2147534191 @default.
- W2115348517 cites W2148354523 @default.
- W2115348517 cites W2152504473 @default.
- W2115348517 cites W2162614738 @default.
- W2115348517 cites W2166690710 @default.
- W2115348517 cites W2166870017 @default.
- W2115348517 cites W2299492101 @default.
- W2115348517 cites W2396242620 @default.
- W2115348517 doi "https://doi.org/10.1002/dvdy.20668" @default.
- W2115348517 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16397896" @default.
- W2115348517 hasPublicationYear "2006" @default.
- W2115348517 type Work @default.
- W2115348517 sameAs 2115348517 @default.
- W2115348517 citedByCount "46" @default.
- W2115348517 countsByYear W21153485172012 @default.
- W2115348517 countsByYear W21153485172013 @default.
- W2115348517 countsByYear W21153485172015 @default.
- W2115348517 countsByYear W21153485172016 @default.
- W2115348517 countsByYear W21153485172017 @default.
- W2115348517 countsByYear W21153485172018 @default.
- W2115348517 countsByYear W21153485172019 @default.
- W2115348517 countsByYear W21153485172021 @default.
- W2115348517 countsByYear W21153485172022 @default.
- W2115348517 countsByYear W21153485172023 @default.
- W2115348517 crossrefType "journal-article" @default.
- W2115348517 hasAuthorship W2115348517A5020642145 @default.
- W2115348517 hasAuthorship W2115348517A5047263678 @default.
- W2115348517 hasAuthorship W2115348517A5066687791 @default.
- W2115348517 hasConcept C104317684 @default.
- W2115348517 hasConcept C127716648 @default.
- W2115348517 hasConcept C129536746 @default.
- W2115348517 hasConcept C145103041 @default.
- W2115348517 hasConcept C196843134 @default.
- W2115348517 hasConcept C2777164004 @default.
- W2115348517 hasConcept C2780915607 @default.
- W2115348517 hasConcept C54355233 @default.
- W2115348517 hasConcept C66518211 @default.
- W2115348517 hasConcept C86339819 @default.
- W2115348517 hasConcept C86803240 @default.
- W2115348517 hasConcept C87073359 @default.
- W2115348517 hasConcept C95444343 @default.
- W2115348517 hasConceptScore W2115348517C104317684 @default.
- W2115348517 hasConceptScore W2115348517C127716648 @default.
- W2115348517 hasConceptScore W2115348517C129536746 @default.
- W2115348517 hasConceptScore W2115348517C145103041 @default.
- W2115348517 hasConceptScore W2115348517C196843134 @default.
- W2115348517 hasConceptScore W2115348517C2777164004 @default.