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- W2115364257 endingPage "396" @default.
- W2115364257 startingPage "363" @default.
- W2115364257 abstract "Rolling adhesion on vascular surfaces is the first step in recruiting circulating leukocytes, hematopoietic progenitors, or platelets to specific organs or to sites of infection or injury. Rolling requires the rapid yet balanced formation and dissociation of adhesive bonds in the challenging environment of blood flow. This review explores how structurally distinct adhesion receptors interact through mechanically regulated kinetics with their ligands to meet these challenges. Remarkably, increasing force applied to adhesive bonds first prolongs their lifetimes (catch bonds) and then shortens their lifetimes (slip bonds). Catch bonds mediate the counterintuitive phenomenon of flow-enhanced rolling adhesion. Force-regulated disruptions of receptor interdomain or intradomain interactions remote from the ligand-binding surface generate catch bonds. Adhesion receptor dimerization, clustering in membrane domains, and interactions with the cytoskeleton modulate the forces applied to bonds. Both inside-out and outside-in cell signals regulate these processes." @default.
- W2115364257 created "2016-06-24" @default.
- W2115364257 creator A5036800314 @default.
- W2115364257 creator A5043920114 @default.
- W2115364257 date "2010-11-10" @default.
- W2115364257 modified "2023-10-06" @default.
- W2115364257 title "Rolling Cell Adhesion" @default.
- W2115364257 cites W1502078581 @default.
- W2115364257 cites W1531681292 @default.
- W2115364257 cites W1538504702 @default.
- W2115364257 cites W1557239654 @default.
- W2115364257 cites W1633422929 @default.
- W2115364257 cites W1933376653 @default.
- W2115364257 cites W1955338813 @default.
- W2115364257 cites W1965086435 @default.
- W2115364257 cites W1966126942 @default.
- W2115364257 cites W1967906263 @default.
- W2115364257 cites W1969000446 @default.
- W2115364257 cites W1969419418 @default.
- W2115364257 cites W1969721828 @default.
- W2115364257 cites W1971783741 @default.
- W2115364257 cites W1973897127 @default.
- W2115364257 cites W1974172048 @default.
- W2115364257 cites W1977100656 @default.
- W2115364257 cites W1981204372 @default.
- W2115364257 cites W1981594687 @default.
- W2115364257 cites W1982037165 @default.
- W2115364257 cites W1984335380 @default.
- W2115364257 cites W1984845371 @default.
- W2115364257 cites W1985173030 @default.
- W2115364257 cites W1985524929 @default.
- W2115364257 cites W1987174800 @default.
- W2115364257 cites W1987263460 @default.
- W2115364257 cites W1987610942 @default.
- W2115364257 cites W1988033018 @default.
- W2115364257 cites W1989978944 @default.
- W2115364257 cites W1990942416 @default.
- W2115364257 cites W1991254311 @default.
- W2115364257 cites W1994331544 @default.
- W2115364257 cites W1995781008 @default.
- W2115364257 cites W2004432012 @default.
- W2115364257 cites W2006070959 @default.
- W2115364257 cites W2008415358 @default.
- W2115364257 cites W2009264307 @default.
- W2115364257 cites W2010080800 @default.
- W2115364257 cites W2011629831 @default.
- W2115364257 cites W2012112908 @default.
- W2115364257 cites W2012275753 @default.
- W2115364257 cites W2012683574 @default.
- W2115364257 cites W2012713768 @default.
- W2115364257 cites W2016531738 @default.
- W2115364257 cites W2017184182 @default.
- W2115364257 cites W2017873104 @default.
- W2115364257 cites W2022755299 @default.
- W2115364257 cites W2023458662 @default.
- W2115364257 cites W2025735516 @default.
- W2115364257 cites W2027414724 @default.
- W2115364257 cites W2027551044 @default.
- W2115364257 cites W2029812241 @default.
- W2115364257 cites W2030549554 @default.
- W2115364257 cites W2030594652 @default.
- W2115364257 cites W2031261181 @default.
- W2115364257 cites W2033320607 @default.
- W2115364257 cites W2033821350 @default.
- W2115364257 cites W2035809865 @default.
- W2115364257 cites W2038800531 @default.
- W2115364257 cites W2040061251 @default.
- W2115364257 cites W2041310039 @default.
- W2115364257 cites W2042371636 @default.
- W2115364257 cites W2044505929 @default.
- W2115364257 cites W2044890797 @default.
- W2115364257 cites W2046737206 @default.
- W2115364257 cites W2051369945 @default.
- W2115364257 cites W2052192720 @default.
- W2115364257 cites W2055596401 @default.
- W2115364257 cites W2056565413 @default.
- W2115364257 cites W2057642577 @default.
- W2115364257 cites W2058268269 @default.
- W2115364257 cites W2062212084 @default.
- W2115364257 cites W2063559096 @default.
- W2115364257 cites W2063952895 @default.
- W2115364257 cites W2064261433 @default.
- W2115364257 cites W2067159154 @default.
- W2115364257 cites W2068262290 @default.
- W2115364257 cites W2068603247 @default.
- W2115364257 cites W2068738605 @default.
- W2115364257 cites W2069193445 @default.
- W2115364257 cites W2070351771 @default.
- W2115364257 cites W2075013504 @default.
- W2115364257 cites W2077393770 @default.
- W2115364257 cites W2084445306 @default.
- W2115364257 cites W2084630883 @default.
- W2115364257 cites W2084677920 @default.
- W2115364257 cites W2085371331 @default.
- W2115364257 cites W2087308464 @default.
- W2115364257 cites W2088900101 @default.
- W2115364257 cites W2091767454 @default.
- W2115364257 cites W2091913466 @default.