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- W2115379951 abstract "Baculoviruses are lethal pathogens of insects, predominantly of the order Lepidoptera. These viruses have a bi-phasic life cycle, which greatly facilitates their use for biotechnological applications. They were exploited initially as biocontrol agents, and then engineered as protein expression vectors. The baculovirus expression vector system (BEVS) is now widely used for recombinant protein production. More recently they have become a popular choice for development as gene delivery and expression vectors in mammalian cells. This article reviews some of the major developments and patents relating to baculoviruses since their initial use as an expression tool and investigates current technologies alleviating bottlenecks in recombinant gene expression in insect cells." @default.
- W2115379951 created "2016-06-24" @default.
- W2115379951 creator A5041200047 @default.
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- W2115379951 date "2009-01-01" @default.
- W2115379951 modified "2023-10-13" @default.
- W2115379951 title "Baculovirus Expression Systems for Recombinant Protein Production in Insect Cells" @default.
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- W2115379951 doi "https://doi.org/10.2174/187220809787172669" @default.
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