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- W2115489314 abstract "Shiga toxin-producing Escherichia coli (STEC) is a group of pathogens which cause gastrointestinal disease in humans and have been associated with numerous food-borne outbreaks worldwide. The intimin adhesin has been considered for many years to be the only colonization factor in these strains. However, the rapid progress in whole-genome sequencing of different STEC serotypes has accelerated the discovery of other adhesins (fimbrial and afimbrial), which have emerged as important contributors to the intestinal colonization occurring during STEC infection. This review summarizes recent progress to identify and characterize, at the molecular level, novel adhesion and colonization factors in STEC strains, with an emphasis on their contribution to virulence traits, their host-pathogen interactions, the regulatory mechanisms controlling their expression, and their role as targets eliciting immune responses in the host." @default.
- W2115489314 created "2016-06-24" @default.
- W2115489314 creator A5016550228 @default.
- W2115489314 creator A5017963202 @default.
- W2115489314 date "2012-03-01" @default.
- W2115489314 modified "2023-10-16" @default.
- W2115489314 title "Molecular Mechanisms That Mediate Colonization of Shiga Toxin-Producing Escherichia coli Strains" @default.
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