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• W2115590697 abstract "<h3>Background</h3> The differential diagnosis between malignant mesothelioma (MM) and metastatic lung adenocarcinoma (MLA) often relies on immunohistochemical studies, with no individual immunomarker holding satisfactory discrimination ability. <h3>Methods</h3> We investigated the diagnostic accuracy of CD24 immunoreactivity on 134 patients including 69 cases of MM and 65 MLA. <h3>Results</h3> The expression of CD24 favoured MLA, with 57/65 cases showing positive cytoplasmic staining compared with 9/69 MM (p<0.001), whose immunopositivity pattern was prevalently membranous (7/9 cases). <h3>Conclusions</h3> CD24 positivity can accurately discriminate MM from MLA. Prospective studies are warranted to clarify whether CD24 could integrate with other immunomarkers to facilitate the diagnosis of mesothelial malignancies." @default.
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• W2115590697 date "2012-10-19" @default.
• W2115590697 modified "2023-09-25" @default.
• W2115590697 title "CD24: a potential new marker in differentiating malignant mesothelioma from pulmonary adenocarcinoma" @default.
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• W2115590697 doi "https://doi.org/10.1136/jclinpath-2012-201020" @default.
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