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- W2115626643 abstract "In this study, 75 Shiga toxin (Stx)-producing Escherichia coli (STEC) strains originating from foods (n = 73) and drinking water (n = 2) were analyzed for their stx genotype, as well as for further chromosome-, phage-, and plasmid-encoded virulence factors. A broad spectrum of stx genes was detected. Fifty-three strains (70.7%) contained stx(2) or stx(2) variants, including stx(2d), mucus-activatable stx(2d), stx(2e), and stx(2g). Seven strains (9.3%) harbored stx(1) or stx(1c), and 15 strains (20.0%) carried both stx(2) and/or stx(2) variants and stx(1) or stx(1c). Beside stx, the most abundant accessory virulence markers in STEC food isolates were iha (57.3%), ehxA (40.0%), espP (28.0%), and subAB (25.3%). Only four strains were eae positive; three of these belonged to the serogroups O26, O103, and O157 and contained a typical enterohemorrhagic E. coli virulence spectrum. The results of this study show that a number of STEC strains that occur in foods appear to be pathogenic for humans, based on their virulence profiles. Analysis of stx subtypes and detection of additional virulence factors in eae-negative strains may help to better assess the risk of such strains for causing human infection." @default.
- W2115626643 created "2016-06-24" @default.
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- W2115626643 date "2009-10-01" @default.
- W2115626643 modified "2023-10-16" @default.
- W2115626643 title "Molecular Analysis of Virulence Profiles and Shiga Toxin Genes in Food-Borne Shiga Toxin-Producing Escherichia coli" @default.
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- W2115626643 doi "https://doi.org/10.1128/aem.00874-09" @default.
- W2115626643 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2753087" @default.
- W2115626643 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19684176" @default.
- W2115626643 hasPublicationYear "2009" @default.
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