FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2115840539> ?p ?o ?g. }

• W2115840539 endingPage "173" @default.
• W2115840539 startingPage "167" @default.
• W2115840539 abstract "We conducted a double-blind, placebo-controlled clinical trial to demonstrate the efficacy of nitazoxanide suspension for the treatment of presumed infectious diarrhea in children. Eligible patients must have had diarrheal illness lasting 3-29 days. Patients were randomized to receive either nitazoxanide or placebo twice daily for three days. The primary endpoint was time from first dose to resolution of symptoms. One hundred children mean age 3.3 years were enrolled. The median time to resolution of symptoms for nitazoxanide treated patients was 23 hours (IQR 4-48 hours) vs 103.5 hours (IQR 63->168 hours) for placebo (p<0.001). An analysis by disease subset indicated nitazoxanide treated patients had statistically shorter durations of diarrheal illness associated with Giardia lamblia (n=32, p<0.001) and those with no identified enteropathogen (n=38, p=0.008), when compared to placebo. The study medication was well tolerated. Overall, nitazoxanide was effective at reducing the duration of diarrheal illness associated with multiple etiologies, including patients with no identified enteropathogen. These results suggest nitazoxanide may be a viable therapeutic option for the empiric treatment of diarrheal illness in children where the etiology is unknown or presumed to be of infectious origin. Clinical trial registry number NCT01326338." @default.
• W2115840539 created "2016-06-24" @default.
• W2115840539 creator A5044155525 @default.
• W2115840539 creator A5052732847 @default.
• W2115840539 creator A5073071485 @default.
• W2115840539 creator A5073072963 @default.
• W2115840539 creator A5073595878 @default.
• W2115840539 date "2012-03-01" @default.
• W2115840539 modified "2023-10-18" @default.
• W2115840539 title "Nitazoxanide for the empiric treatment of pediatric infectious diarrhea" @default.
• W2115840539 cites W1584262266 @default.
• W2115840539 cites W1978271621 @default.
• W2115840539 cites W1981173411 @default.
• W2115840539 cites W1994729182 @default.
• W2115840539 cites W2005562083 @default.
• W2115840539 cites W2018663404 @default.
• W2115840539 cites W2056007377 @default.
• W2115840539 cites W2063700381 @default.
• W2115840539 cites W2074730909 @default.
• W2115840539 cites W2086715367 @default.
• W2115840539 cites W2088399547 @default.
• W2115840539 cites W2095322104 @default.
• W2115840539 cites W2096031010 @default.
• W2115840539 cites W2104952890 @default.
• W2115840539 cites W2109524284 @default.
• W2115840539 cites W2112290804 @default.
• W2115840539 cites W2114106142 @default.
• W2115840539 cites W2116905112 @default.
• W2115840539 cites W2122152652 @default.
• W2115840539 cites W2126983680 @default.
• W2115840539 cites W2127653958 @default.
• W2115840539 cites W2128105614 @default.
• W2115840539 cites W2131381620 @default.
• W2115840539 cites W2133153279 @default.
• W2115840539 cites W2141042056 @default.
• W2115840539 cites W2146097876 @default.
• W2115840539 cites W2149272038 @default.
• W2115840539 cites W2149892566 @default.
• W2115840539 cites W2151279031 @default.
• W2115840539 cites W2152035272 @default.
• W2115840539 cites W2160454557 @default.
• W2115840539 cites W2168033293 @default.
• W2115840539 cites W2170200960 @default.
• W2115840539 doi "https://doi.org/10.1016/j.trstmh.2011.11.007" @default.
• W2115840539 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22301075" @default.
• W2115840539 hasPublicationYear "2012" @default.
• W2115840539 type Work @default.
• W2115840539 sameAs 2115840539 @default.
• W2115840539 citedByCount "42" @default.
• W2115840539 countsByYear W21158405392012 @default.
• W2115840539 countsByYear W21158405392013 @default.
• W2115840539 countsByYear W21158405392014 @default.
• W2115840539 countsByYear W21158405392015 @default.
• W2115840539 countsByYear W21158405392016 @default.
• W2115840539 countsByYear W21158405392017 @default.
• W2115840539 countsByYear W21158405392018 @default.
• W2115840539 countsByYear W21158405392019 @default.
• W2115840539 countsByYear W21158405392020 @default.
• W2115840539 countsByYear W21158405392021 @default.
• W2115840539 countsByYear W21158405392023 @default.
• W2115840539 crossrefType "journal-article" @default.
• W2115840539 hasAuthorship W2115840539A5044155525 @default.
• W2115840539 hasAuthorship W2115840539A5052732847 @default.
• W2115840539 hasAuthorship W2115840539A5073071485 @default.
• W2115840539 hasAuthorship W2115840539A5073072963 @default.
• W2115840539 hasAuthorship W2115840539A5073595878 @default.
• W2115840539 hasConcept C126322002 @default.
• W2115840539 hasConcept C137627325 @default.
• W2115840539 hasConcept C142724271 @default.
• W2115840539 hasConcept C187212893 @default.
• W2115840539 hasConcept C203092338 @default.
• W2115840539 hasConcept C204787440 @default.
• W2115840539 hasConcept C27081682 @default.
• W2115840539 hasConcept C2777276848 @default.
• W2115840539 hasConcept C2779802037 @default.
• W2115840539 hasConcept C535046627 @default.
• W2115840539 hasConcept C71924100 @default.
• W2115840539 hasConceptScore W2115840539C126322002 @default.
• W2115840539 hasConceptScore W2115840539C137627325 @default.
• W2115840539 hasConceptScore W2115840539C142724271 @default.
• W2115840539 hasConceptScore W2115840539C187212893 @default.
• W2115840539 hasConceptScore W2115840539C203092338 @default.
• W2115840539 hasConceptScore W2115840539C204787440 @default.
• W2115840539 hasConceptScore W2115840539C27081682 @default.
• W2115840539 hasConceptScore W2115840539C2777276848 @default.
• W2115840539 hasConceptScore W2115840539C2779802037 @default.
• W2115840539 hasConceptScore W2115840539C535046627 @default.
• W2115840539 hasConceptScore W2115840539C71924100 @default.
• W2115840539 hasIssue "3" @default.
• W2115840539 hasLocation W21158405391 @default.
• W2115840539 hasLocation W21158405392 @default.
• W2115840539 hasOpenAccess W2115840539 @default.
• W2115840539 hasPrimaryLocation W21158405391 @default.
• W2115840539 hasRelatedWork W1991948947 @default.
• W2115840539 hasRelatedWork W2036346027 @default.
• W2115840539 hasRelatedWork W2051665346 @default.
• W2115840539 hasRelatedWork W2086715367 @default.
• W2115840539 hasRelatedWork W2126313057 @default.

• next