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- W2115849571 abstract "Common marmosets with bilateral ibotenic acid-induced destruction of the neurones of the vertical limb of the diagonal band of Broca, which provide the major cholinergic input to the hippocampal formation, were impaired on the acquisition but not on the retention of a repeated-trial visuospatial discrimination learning task. They were also impaired on serial spatial reversal learning (but not on serial object reversal learning), on acquisition of a trial-independent successive concurrent discrimination using novel objects (but not on acquisition of a comparable discrimination in which two familiar objects had predictable reward value) and were unable to acquire a difficult conditional object discrimination. It is argued that the role of the hippocampus is in the acquisition but not the retention of ruled-based behaviour (which includes spatial responding) in contrast to the acquistion of discriminations based on stimulus-reward association formation." @default.
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- W2115849571 date "1989-11-01" @default.
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- W2115849571 title "Learning about rules but not about reward is impaired following lesions of the cholinergic projection to the hippocampus" @default.
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- W2115849571 doi "https://doi.org/10.1016/0006-8993(89)90626-4" @default.
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