Matches in SemOpenAlex for { <https://semopenalex.org/work/W2115859232> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2115859232 abstract "The effects of (-)-isoproterenol covalently linked to glass beads on inotropic state, cyclic AMP concentration, and phosphorylase b to a conversion was studied in cat and guinea pig papillary muscles. Biochemical responses also were measured in mouse diaphragm sections. In cat papillary muscles under normal conditions and in guinea pig muscles partly depolarized with 22 mM K+ an increased inotropic state and phosphorylase activation could be dissociated from the formation of cyclic AMP. This contrasts with close correlation reported between isometric tension and cyclic AMP concentration in guinea pig papillary muscles exposed to varying concentrations of isoproterenol dissolved in the bath medium. The cyclic nucleotide did increase in guinea pig papillary muscles exposed to a freshly prepared batch of isoproterenol beads and in the mouse diaphragms. The type and age of the bead preparation had marked effects on all responses that were measured and on the rate of leakage of biologically active products from the beads. Nevertheless, experimental conditions could be obtained under which the initiation of the contractile and biochemical responses was probably limited to intense stimulation of receptors at or near the points of contact between beads and muscle and not due to gross leakage into the bath. The results indicate that cyclic AMP is probably involved in the initiation but not the propagation of the inotropic response of papillary muscles exposed to isoproterenol glass beads." @default.
- W2115859232 created "2016-06-24" @default.
- W2115859232 creator A5000412024 @default.
- W2115859232 creator A5050791253 @default.
- W2115859232 creator A5064505102 @default.
- W2115859232 creator A5081572157 @default.
- W2115859232 date "1977-05-01" @default.
- W2115859232 modified "2023-09-24" @default.
- W2115859232 title "Contractile and biochemical responses of cardiac and skeletal muscle to isoproterenol covalently linked to glass beads." @default.
- W2115859232 cites W1161647098 @default.
- W2115859232 cites W1538880915 @default.
- W2115859232 cites W1562695172 @default.
- W2115859232 cites W1995197959 @default.
- W2115859232 cites W1998543829 @default.
- W2115859232 cites W2000037456 @default.
- W2115859232 cites W2021702488 @default.
- W2115859232 cites W2025761011 @default.
- W2115859232 cites W2080671419 @default.
- W2115859232 cites W2095226919 @default.
- W2115859232 cites W2095691742 @default.
- W2115859232 cites W2099789371 @default.
- W2115859232 cites W2120847061 @default.
- W2115859232 cites W2160769344 @default.
- W2115859232 cites W2169155912 @default.
- W2115859232 cites W2323408701 @default.
- W2115859232 cites W955285178 @default.
- W2115859232 doi "https://doi.org/10.1161/01.res.40.5.474" @default.
- W2115859232 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/192486" @default.
- W2115859232 hasPublicationYear "1977" @default.
- W2115859232 type Work @default.
- W2115859232 sameAs 2115859232 @default.
- W2115859232 citedByCount "19" @default.
- W2115859232 crossrefType "journal-article" @default.
- W2115859232 hasAuthorship W2115859232A5000412024 @default.
- W2115859232 hasAuthorship W2115859232A5050791253 @default.
- W2115859232 hasAuthorship W2115859232A5064505102 @default.
- W2115859232 hasAuthorship W2115859232A5081572157 @default.
- W2115859232 hasBestOaLocation W21158592321 @default.
- W2115859232 hasConcept C103486182 @default.
- W2115859232 hasConcept C126322002 @default.
- W2115859232 hasConcept C134018914 @default.
- W2115859232 hasConcept C155710745 @default.
- W2115859232 hasConcept C181199279 @default.
- W2115859232 hasConcept C185592680 @default.
- W2115859232 hasConcept C204779464 @default.
- W2115859232 hasConcept C24998067 @default.
- W2115859232 hasConcept C2776090920 @default.
- W2115859232 hasConcept C2777274916 @default.
- W2115859232 hasConcept C2778815084 @default.
- W2115859232 hasConcept C2778996579 @default.
- W2115859232 hasConcept C519063684 @default.
- W2115859232 hasConcept C55493867 @default.
- W2115859232 hasConcept C71924100 @default.
- W2115859232 hasConcept C86803240 @default.
- W2115859232 hasConceptScore W2115859232C103486182 @default.
- W2115859232 hasConceptScore W2115859232C126322002 @default.
- W2115859232 hasConceptScore W2115859232C134018914 @default.
- W2115859232 hasConceptScore W2115859232C155710745 @default.
- W2115859232 hasConceptScore W2115859232C181199279 @default.
- W2115859232 hasConceptScore W2115859232C185592680 @default.
- W2115859232 hasConceptScore W2115859232C204779464 @default.
- W2115859232 hasConceptScore W2115859232C24998067 @default.
- W2115859232 hasConceptScore W2115859232C2776090920 @default.
- W2115859232 hasConceptScore W2115859232C2777274916 @default.
- W2115859232 hasConceptScore W2115859232C2778815084 @default.
- W2115859232 hasConceptScore W2115859232C2778996579 @default.
- W2115859232 hasConceptScore W2115859232C519063684 @default.
- W2115859232 hasConceptScore W2115859232C55493867 @default.
- W2115859232 hasConceptScore W2115859232C71924100 @default.
- W2115859232 hasConceptScore W2115859232C86803240 @default.
- W2115859232 hasLocation W21158592321 @default.
- W2115859232 hasLocation W21158592322 @default.
- W2115859232 hasOpenAccess W2115859232 @default.
- W2115859232 hasPrimaryLocation W21158592321 @default.
- W2115859232 hasRelatedWork W1822319839 @default.
- W2115859232 hasRelatedWork W1978559347 @default.
- W2115859232 hasRelatedWork W2033761402 @default.
- W2115859232 hasRelatedWork W2072811299 @default.
- W2115859232 hasRelatedWork W2115859232 @default.
- W2115859232 hasRelatedWork W2123268758 @default.
- W2115859232 hasRelatedWork W2406900103 @default.
- W2115859232 hasRelatedWork W2417077403 @default.
- W2115859232 hasRelatedWork W2472921175 @default.
- W2115859232 hasRelatedWork W2952823062 @default.
- W2115859232 isParatext "false" @default.
- W2115859232 isRetracted "false" @default.
- W2115859232 magId "2115859232" @default.
- W2115859232 workType "article" @default.