Matches in SemOpenAlex for { <https://semopenalex.org/work/W2115859816> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2115859816 endingPage "345" @default.
- W2115859816 startingPage "335" @default.
- W2115859816 abstract "The activities of 17β-hydroxysteroid dehydrogenase and of some NADPH-generating enzymes in the fetal mouse testis during the formation of the accessory reproductive glands indicate that Leydig cells synthesize androgens before gonadotropins are secreted. In the neonatal testis the seminiferous tubules grow rapidly and the relative volume of the intertubular tissues decreases. At the same time the absolute activity of 17βSDH also decreases but there is no evident loss of enzyme activity as the primary spermatocytes begin meiotic prophase. High levels of NADPH-generating malic enzyme activity coincide with the onset of meiosis and the development of the spermatids, although the activity of 17βSDH remains constant. Both glucose-6-phosphate and isocitrate dehydrogenases, which can be activated by gonadotropin, show strong activity prior to spermiogenesis. Significantly increased activities of 17βSDH and the ME occur in 10-day postpartum intact mice four hours after a single injection of 0.25 unit ICSH. Exogenous gonadotropin stimulates G6PDH and IDH activities during divisions of spermatogonia five days after birth. The pituitary-Leydig cell axis is stabilized after the beginning of meiosis so exogenous ICSH has little effect on testicular enzymes during the remainder of the first wave of spermatogenesis. Dependence of Leydig cell activities on pituitary gonadotropin seems to occur during pachytene or the early stages of spermatid formation. Androgen synthesis in the murine testis may be associated with the NADPH-generating ME and IDH as well as G6PDH which has been implicated in other steroidogenic tissues." @default.
- W2115859816 created "2016-06-24" @default.
- W2115859816 creator A5021520963 @default.
- W2115859816 date "1968-11-01" @default.
- W2115859816 modified "2023-09-27" @default.
- W2115859816 title "Effect of the interstitial-cell-stimulating hormone on testicular enzymes during spermatogenesis" @default.
- W2115859816 cites W10633288 @default.
- W2115859816 cites W1503565230 @default.
- W2115859816 cites W1977794236 @default.
- W2115859816 cites W1980380663 @default.
- W2115859816 cites W1991063983 @default.
- W2115859816 cites W1997202578 @default.
- W2115859816 cites W1997663825 @default.
- W2115859816 cites W2014409897 @default.
- W2115859816 cites W2018934034 @default.
- W2115859816 cites W2043320564 @default.
- W2115859816 cites W2046097211 @default.
- W2115859816 cites W2046678764 @default.
- W2115859816 cites W2052557407 @default.
- W2115859816 cites W2064446194 @default.
- W2115859816 cites W2073155020 @default.
- W2115859816 cites W2075818006 @default.
- W2115859816 cites W2081640493 @default.
- W2115859816 cites W2084134725 @default.
- W2115859816 cites W2091050119 @default.
- W2115859816 cites W2130150770 @default.
- W2115859816 cites W2136089457 @default.
- W2115859816 cites W2142912283 @default.
- W2115859816 cites W2145397007 @default.
- W2115859816 cites W2153832418 @default.
- W2115859816 cites W2164858924 @default.
- W2115859816 cites W2289132126 @default.
- W2115859816 cites W3118710269 @default.
- W2115859816 cites W4236945656 @default.
- W2115859816 doi "https://doi.org/10.1002/jez.1401690307" @default.
- W2115859816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5752051" @default.
- W2115859816 hasPublicationYear "1968" @default.
- W2115859816 type Work @default.
- W2115859816 sameAs 2115859816 @default.
- W2115859816 citedByCount "8" @default.
- W2115859816 countsByYear W21158598162021 @default.
- W2115859816 crossrefType "journal-article" @default.
- W2115859816 hasAuthorship W2115859816A5021520963 @default.
- W2115859816 hasConcept C104317684 @default.
- W2115859816 hasConcept C123765429 @default.
- W2115859816 hasConcept C126322002 @default.
- W2115859816 hasConcept C134018914 @default.
- W2115859816 hasConcept C148196450 @default.
- W2115859816 hasConcept C16685009 @default.
- W2115859816 hasConcept C2777394357 @default.
- W2115859816 hasConcept C2777736315 @default.
- W2115859816 hasConcept C2778575703 @default.
- W2115859816 hasConcept C2778619154 @default.
- W2115859816 hasConcept C2778782382 @default.
- W2115859816 hasConcept C2779122487 @default.
- W2115859816 hasConcept C2779279991 @default.
- W2115859816 hasConcept C55493867 @default.
- W2115859816 hasConcept C71315377 @default.
- W2115859816 hasConcept C71924100 @default.
- W2115859816 hasConcept C86803240 @default.
- W2115859816 hasConceptScore W2115859816C104317684 @default.
- W2115859816 hasConceptScore W2115859816C123765429 @default.
- W2115859816 hasConceptScore W2115859816C126322002 @default.
- W2115859816 hasConceptScore W2115859816C134018914 @default.
- W2115859816 hasConceptScore W2115859816C148196450 @default.
- W2115859816 hasConceptScore W2115859816C16685009 @default.
- W2115859816 hasConceptScore W2115859816C2777394357 @default.
- W2115859816 hasConceptScore W2115859816C2777736315 @default.
- W2115859816 hasConceptScore W2115859816C2778575703 @default.
- W2115859816 hasConceptScore W2115859816C2778619154 @default.
- W2115859816 hasConceptScore W2115859816C2778782382 @default.
- W2115859816 hasConceptScore W2115859816C2779122487 @default.
- W2115859816 hasConceptScore W2115859816C2779279991 @default.
- W2115859816 hasConceptScore W2115859816C55493867 @default.
- W2115859816 hasConceptScore W2115859816C71315377 @default.
- W2115859816 hasConceptScore W2115859816C71924100 @default.
- W2115859816 hasConceptScore W2115859816C86803240 @default.
- W2115859816 hasIssue "3" @default.
- W2115859816 hasLocation W21158598161 @default.
- W2115859816 hasLocation W21158598162 @default.
- W2115859816 hasOpenAccess W2115859816 @default.
- W2115859816 hasPrimaryLocation W21158598161 @default.
- W2115859816 hasRelatedWork W1976688049 @default.
- W2115859816 hasRelatedWork W2012502375 @default.
- W2115859816 hasRelatedWork W2018478270 @default.
- W2115859816 hasRelatedWork W2035245144 @default.
- W2115859816 hasRelatedWork W2057000165 @default.
- W2115859816 hasRelatedWork W2072808685 @default.
- W2115859816 hasRelatedWork W2136785547 @default.
- W2115859816 hasRelatedWork W2316581151 @default.
- W2115859816 hasRelatedWork W4231554407 @default.
- W2115859816 hasRelatedWork W2411910748 @default.
- W2115859816 hasVolume "169" @default.
- W2115859816 isParatext "false" @default.
- W2115859816 isRetracted "false" @default.
- W2115859816 magId "2115859816" @default.
- W2115859816 workType "article" @default.