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- W2115955381 abstract "Mast cells are restricted to the leptomeninges and thalamus of healthy mice. These populations are increased by stress and highly sensitive to reproductive hormones. To examine the influence of nociception, a form of stress, on thalamic mast cells, we ligated the left fifth lumbar spinal nerve of male and female mice to induce hyperalgesia. Two, 7 and 14 days later, mice were killed and thalami examined histologically using toluidine blue stain. The total number of thalamic mast cells was not influenced by ligation of the spinal nerve compared to sham-operation in either female or male mice. However, in females, the percent of thalamic mast cells located on the side of the thalamus contralateral to the ligation was greater on days 2 and 7, coincident with mechanical hyperalgesia. At these times, areas in which mast cells were most dense contralateral to nerve-injury included the posterior (Po) and lateral geniculate (LG) nuclei compared to their symmetrical distribution in sham-operated mice. These data suggest that local nociceptive signals to each side of the thalamus rather than stress hormones influence the location of mast cells during the development of allodynia and hyperalgesia. In addition, both hyperalgesia and mast cell distribution induced by nerve-ligation differ in females compared to males, reflecting a novel neuroimmune response to pain within the CNS." @default.
- W2115955381 created "2016-06-24" @default.
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- W2115955381 date "2005-03-01" @default.
- W2115955381 modified "2023-10-14" @default.
- W2115955381 title "Unilateral spinal nerve ligation leads to an asymmetrical distribution of mast cells in the thalamus of female but not male mice" @default.
- W2115955381 cites W1533115076 @default.
- W2115955381 cites W1566175888 @default.
- W2115955381 cites W1946950710 @default.
- W2115955381 cites W1958281454 @default.
- W2115955381 cites W1963587204 @default.
- W2115955381 cites W1963628498 @default.
- W2115955381 cites W1963785160 @default.
- W2115955381 cites W1965866432 @default.
- W2115955381 cites W1966657043 @default.
- W2115955381 cites W1968161007 @default.
- W2115955381 cites W1969887614 @default.
- W2115955381 cites W1971107903 @default.
- W2115955381 cites W1972081947 @default.
- W2115955381 cites W1983402669 @default.
- W2115955381 cites W1989469817 @default.
- W2115955381 cites W1989875279 @default.
- W2115955381 cites W1990177635 @default.
- W2115955381 cites W1995261715 @default.
- W2115955381 cites W1995605020 @default.
- W2115955381 cites W1998138279 @default.
- W2115955381 cites W1998783767 @default.
- W2115955381 cites W1998950078 @default.
- W2115955381 cites W1999555237 @default.
- W2115955381 cites W2000976225 @default.
- W2115955381 cites W2001134995 @default.
- W2115955381 cites W2002759179 @default.
- W2115955381 cites W2005285448 @default.
- W2115955381 cites W2009323482 @default.
- W2115955381 cites W2011746291 @default.
- W2115955381 cites W2024905784 @default.
- W2115955381 cites W2027880398 @default.
- W2115955381 cites W2029619172 @default.
- W2115955381 cites W2032609932 @default.
- W2115955381 cites W2034949619 @default.
- W2115955381 cites W2036323596 @default.
- W2115955381 cites W2036755824 @default.
- W2115955381 cites W2041180516 @default.
- W2115955381 cites W2044722385 @default.
- W2115955381 cites W2047107707 @default.
- W2115955381 cites W2049124574 @default.
- W2115955381 cites W2051311776 @default.
- W2115955381 cites W2052797473 @default.
- W2115955381 cites W2057710446 @default.
- W2115955381 cites W2062848007 @default.
- W2115955381 cites W2064145368 @default.
- W2115955381 cites W2064731181 @default.
- W2115955381 cites W2064781600 @default.
- W2115955381 cites W2066347302 @default.
- W2115955381 cites W2066526154 @default.
- W2115955381 cites W2067523166 @default.
- W2115955381 cites W2068406701 @default.
- W2115955381 cites W2070777089 @default.
- W2115955381 cites W2074861021 @default.
- W2115955381 cites W2078446214 @default.
- W2115955381 cites W2082840812 @default.
- W2115955381 cites W2089236297 @default.
- W2115955381 cites W2089593753 @default.
- W2115955381 cites W2091523643 @default.
- W2115955381 cites W2093703392 @default.
- W2115955381 cites W2099173554 @default.
- W2115955381 cites W2099871304 @default.
- W2115955381 cites W2118358218 @default.
- W2115955381 cites W2119250252 @default.
- W2115955381 cites W2131724028 @default.
- W2115955381 cites W2137789711 @default.
- W2115955381 cites W2158649743 @default.
- W2115955381 cites W2169613767 @default.
- W2115955381 cites W2339022261 @default.
- W2115955381 cites W4239604700 @default.
- W2115955381 cites W4244361698 @default.
- W2115955381 cites W4248558388 @default.
- W2115955381 cites W4375932165 @default.
- W2115955381 doi "https://doi.org/10.1016/j.pain.2004.12.002" @default.
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