FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2115992829> ?p ?o ?g. }

• W2115992829 endingPage "521" @default.
• W2115992829 startingPage "513" @default.
• W2115992829 abstract "Ribonucleotide reductase, an enzyme found in all prokaryotic and eukaryotic cells that synthesize DNA, is induced by herpes simplex virus (HSV). In this study the effect of anti-HSV antiserum on the induced ribonucleotide reductase has been examined and the ability of different temperature-sensitive (ts) mutants of HSV-1 to induce the enzyme has been investigated. The HSV-1-induced ribonucleotide reductase was inhibited by antiserum raised against infected cell lysates but not by preimmune serum. The wild-type (ts+) virus induced similar levels of ribonucleotide reductase at 31 degrees C and 38.5 degrees C (the permissive and non-permissive temperatures respectively for the ts mutants). All ts mutants induced approximately wild-type levels of the enzyme at 31 degrees C. At 38.5 degrees C, two of the four ts mutants studied also induced wild-type levels of enzyme but ts G failed to induce any activity while ts K induced variable but low levels. The enzyme activity induced by ts G at 31 degrees C was thermolabile both in vivo and in vitro. These results provide the first strong evidence that the induced ribonucleotide reductase activity is at least partially virus-coded." @default.
• W2115992829 created "2016-06-24" @default.
• W2115992829 creator A5002247050 @default.
• W2115992829 date "1983-03-01" @default.
• W2115992829 modified "2023-09-23" @default.
• W2115992829 title "Ribonucleotide Reductase Induced by Herpes Simplex Virus has a Virus-specified Constituent" @default.
• W2115992829 cites W1504844653 @default.
• W2115992829 cites W153095713 @default.
• W2115992829 cites W1531035388 @default.
• W2115992829 cites W1595008575 @default.
• W2115992829 cites W1775749144 @default.
• W2115992829 cites W1820557301 @default.
• W2115992829 cites W1862850671 @default.
• W2115992829 cites W1877901924 @default.
• W2115992829 cites W1969813411 @default.
• W2115992829 cites W1970537831 @default.
• W2115992829 cites W1970741404 @default.
• W2115992829 cites W1976756961 @default.
• W2115992829 cites W1983674897 @default.
• W2115992829 cites W1985293411 @default.
• W2115992829 cites W1995556647 @default.
• W2115992829 cites W2019578579 @default.
• W2115992829 cites W2023642720 @default.
• W2115992829 cites W2025384697 @default.
• W2115992829 cites W2043722290 @default.
• W2115992829 cites W2048246686 @default.
• W2115992829 cites W2066827421 @default.
• W2115992829 cites W2069892944 @default.
• W2115992829 cites W2081494804 @default.
• W2115992829 cites W2093475210 @default.
• W2115992829 cites W2114240169 @default.
• W2115992829 cites W2151939374 @default.
• W2115992829 cites W2165554716 @default.
• W2115992829 cites W2178778111 @default.
• W2115992829 cites W2461904519 @default.
• W2115992829 doi "https://doi.org/10.1099/0022-1317-64-3-513" @default.
• W2115992829 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6298343" @default.
• W2115992829 hasPublicationYear "1983" @default.
• W2115992829 type Work @default.
• W2115992829 sameAs 2115992829 @default.
• W2115992829 citedByCount "120" @default.
• W2115992829 countsByYear W21159928292014 @default.
• W2115992829 countsByYear W21159928292015 @default.
• W2115992829 countsByYear W21159928292017 @default.
• W2115992829 crossrefType "journal-article" @default.
• W2115992829 hasAuthorship W2115992829A5002247050 @default.
• W2115992829 hasBestOaLocation W21159928291 @default.
• W2115992829 hasConcept C104292427 @default.
• W2115992829 hasConcept C104317684 @default.
• W2115992829 hasConcept C134651460 @default.
• W2115992829 hasConcept C143065580 @default.
• W2115992829 hasConcept C153911025 @default.
• W2115992829 hasConcept C159047783 @default.
• W2115992829 hasConcept C159654299 @default.
• W2115992829 hasConcept C181199279 @default.
• W2115992829 hasConcept C202751555 @default.
• W2115992829 hasConcept C203014093 @default.
• W2115992829 hasConcept C2522874641 @default.
• W2115992829 hasConcept C2779155592 @default.
• W2115992829 hasConcept C2781196997 @default.
• W2115992829 hasConcept C4710235 @default.
• W2115992829 hasConcept C512185932 @default.
• W2115992829 hasConcept C55493867 @default.
• W2115992829 hasConcept C64241487 @default.
• W2115992829 hasConcept C86803240 @default.
• W2115992829 hasConcept C91523082 @default.
• W2115992829 hasConcept C98892162 @default.
• W2115992829 hasConceptScore W2115992829C104292427 @default.
• W2115992829 hasConceptScore W2115992829C104317684 @default.
• W2115992829 hasConceptScore W2115992829C134651460 @default.
• W2115992829 hasConceptScore W2115992829C143065580 @default.
• W2115992829 hasConceptScore W2115992829C153911025 @default.
• W2115992829 hasConceptScore W2115992829C159047783 @default.
• W2115992829 hasConceptScore W2115992829C159654299 @default.
• W2115992829 hasConceptScore W2115992829C181199279 @default.
• W2115992829 hasConceptScore W2115992829C202751555 @default.
• W2115992829 hasConceptScore W2115992829C203014093 @default.
• W2115992829 hasConceptScore W2115992829C2522874641 @default.
• W2115992829 hasConceptScore W2115992829C2779155592 @default.
• W2115992829 hasConceptScore W2115992829C2781196997 @default.
• W2115992829 hasConceptScore W2115992829C4710235 @default.
• W2115992829 hasConceptScore W2115992829C512185932 @default.
• W2115992829 hasConceptScore W2115992829C55493867 @default.
• W2115992829 hasConceptScore W2115992829C64241487 @default.
• W2115992829 hasConceptScore W2115992829C86803240 @default.
• W2115992829 hasConceptScore W2115992829C91523082 @default.
• W2115992829 hasConceptScore W2115992829C98892162 @default.
• W2115992829 hasIssue "3" @default.
• W2115992829 hasLocation W21159928291 @default.
• W2115992829 hasLocation W21159928292 @default.
• W2115992829 hasOpenAccess W2115992829 @default.
• W2115992829 hasPrimaryLocation W21159928291 @default.
• W2115992829 hasRelatedWork W1752397324 @default.
• W2115992829 hasRelatedWork W1986778880 @default.
• W2115992829 hasRelatedWork W1996498777 @default.
• W2115992829 hasRelatedWork W2016936486 @default.
• W2115992829 hasRelatedWork W2066827421 @default.
• W2115992829 hasRelatedWork W2115992829 @default.

• next