FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2116028075> ?p ?o ?g. }

• W2116028075 endingPage "245" @default.
• W2116028075 startingPage "239" @default.
• W2116028075 abstract "Neutralizing monoclonal antibodies (N-MAbs) to serotype G2 and G4 rotaviruses were used to study intraserotypic variation by selection and characterization of N-MAb-resistant antigenic variants and reaction of N-MAbs with prototype rotavirus strains. Two G2-specific N-MAbs reacted with G2 rotaviruses S2, DS-1, RV-5 and RV-6 but not with 1076. Sequence analysis of the gene encoding VP7 of 1076 virus showed that the differences in amino acid sequence between 1076 virus and the other G2 strains at position 147, 213 and 217 correlated with the loss of N-MAb reactivity. Rotavirus variant mutation mapping data suggested that the amino acid difference at position 213 was likely to be of greatest importance. Rotavirus 1076 was defined as monotype b within G2 strains, whereas S2, DS-1, RV-5 and RV-6 belong to monotype a. The molecular basis for G4 subtypes/monotypes was also studied. The monotype G4b N-MAb 3A3 selected an antigenic variant with an amino acid mutation at position 96, whereas variants of the G4a-reactive N-MAb ST-3:1 showed a mutation at position 94, which produced a new, utilized glycosylation site. Neutralization by N-MAb ST-3:1 was also affected by amino acid changes at position 96. Reactions with these N-MAbs show that serotype G2 viruses can be divided into monotypes and confirm the observation that serotype G4 rotaviruses can be subdivided into subtypes/monotypes a and b. The G2 monotypes relate to differences at particular amino acids within antigenic region C and possibly region B, whereas antigenic region A is most important for G4 monotype differentiation." @default.
• W2116028075 created "2016-06-24" @default.
• W2116028075 creator A5004429723 @default.
• W2116028075 creator A5018580844 @default.
• W2116028075 creator A5022567789 @default.
• W2116028075 creator A5030171291 @default.
• W2116028075 creator A5042513149 @default.
• W2116028075 date "1996-02-01" @default.
• W2116028075 modified "2023-10-05" @default.
• W2116028075 title "Amino acids involved in distinguishing between monotypes of rotavirus G serotypes 2 and 4" @default.
• W2116028075 cites W1514516484 @default.
• W2116028075 cites W1574980295 @default.
• W2116028075 cites W1667485201 @default.
• W2116028075 cites W1745542466 @default.
• W2116028075 cites W1808097902 @default.
• W2116028075 cites W1917812967 @default.
• W2116028075 cites W1920344802 @default.
• W2116028075 cites W1927508411 @default.
• W2116028075 cites W1996437843 @default.
• W2116028075 cites W2007799003 @default.
• W2116028075 cites W2015486029 @default.
• W2116028075 cites W2023050855 @default.
• W2116028075 cites W2025632476 @default.
• W2116028075 cites W2027433479 @default.
• W2116028075 cites W2027754900 @default.
• W2116028075 cites W2039526755 @default.
• W2116028075 cites W2070296246 @default.
• W2116028075 cites W2088781810 @default.
• W2116028075 cites W2089528138 @default.
• W2116028075 cites W2092702475 @default.
• W2116028075 cites W2099992779 @default.
• W2116028075 cites W2138715674 @default.
• W2116028075 cites W2141929055 @default.
• W2116028075 cites W2144836235 @default.
• W2116028075 cites W2325338916 @default.
• W2116028075 doi "https://doi.org/10.1099/0022-1317-77-2-239" @default.
• W2116028075 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8627227" @default.
• W2116028075 hasPublicationYear "1996" @default.
• W2116028075 type Work @default.
• W2116028075 sameAs 2116028075 @default.
• W2116028075 citedByCount "28" @default.
• W2116028075 countsByYear W21160280752014 @default.
• W2116028075 countsByYear W21160280752015 @default.
• W2116028075 countsByYear W21160280752022 @default.
• W2116028075 crossrefType "journal-article" @default.
• W2116028075 hasAuthorship W2116028075A5004429723 @default.
• W2116028075 hasAuthorship W2116028075A5018580844 @default.
• W2116028075 hasAuthorship W2116028075A5022567789 @default.
• W2116028075 hasAuthorship W2116028075A5030171291 @default.
• W2116028075 hasAuthorship W2116028075A5042513149 @default.
• W2116028075 hasBestOaLocation W21160280751 @default.
• W2116028075 hasConcept C10389963 @default.
• W2116028075 hasConcept C104317684 @default.
• W2116028075 hasConcept C147483822 @default.
• W2116028075 hasConcept C153911025 @default.
• W2116028075 hasConcept C159047783 @default.
• W2116028075 hasConcept C159654299 @default.
• W2116028075 hasConcept C167625842 @default.
• W2116028075 hasConcept C191942190 @default.
• W2116028075 hasConcept C2522874641 @default.
• W2116028075 hasConcept C2779416561 @default.
• W2116028075 hasConcept C2781367151 @default.
• W2116028075 hasConcept C501734568 @default.
• W2116028075 hasConcept C515207424 @default.
• W2116028075 hasConcept C542903549 @default.
• W2116028075 hasConcept C54355233 @default.
• W2116028075 hasConcept C86803240 @default.
• W2116028075 hasConceptScore W2116028075C10389963 @default.
• W2116028075 hasConceptScore W2116028075C104317684 @default.
• W2116028075 hasConceptScore W2116028075C147483822 @default.
• W2116028075 hasConceptScore W2116028075C153911025 @default.
• W2116028075 hasConceptScore W2116028075C159047783 @default.
• W2116028075 hasConceptScore W2116028075C159654299 @default.
• W2116028075 hasConceptScore W2116028075C167625842 @default.
• W2116028075 hasConceptScore W2116028075C191942190 @default.
• W2116028075 hasConceptScore W2116028075C2522874641 @default.
• W2116028075 hasConceptScore W2116028075C2779416561 @default.
• W2116028075 hasConceptScore W2116028075C2781367151 @default.
• W2116028075 hasConceptScore W2116028075C501734568 @default.
• W2116028075 hasConceptScore W2116028075C515207424 @default.
• W2116028075 hasConceptScore W2116028075C542903549 @default.
• W2116028075 hasConceptScore W2116028075C54355233 @default.
• W2116028075 hasConceptScore W2116028075C86803240 @default.
• W2116028075 hasIssue "2" @default.
• W2116028075 hasLocation W21160280751 @default.
• W2116028075 hasLocation W21160280752 @default.
• W2116028075 hasOpenAccess W2116028075 @default.
• W2116028075 hasPrimaryLocation W21160280751 @default.
• W2116028075 hasRelatedWork W1730531114 @default.
• W2116028075 hasRelatedWork W1785408368 @default.
• W2116028075 hasRelatedWork W1808097902 @default.
• W2116028075 hasRelatedWork W1987645034 @default.
• W2116028075 hasRelatedWork W2026673299 @default.
• W2116028075 hasRelatedWork W2066707535 @default.
• W2116028075 hasRelatedWork W2071330946 @default.
• W2116028075 hasRelatedWork W2074435673 @default.
• W2116028075 hasRelatedWork W2083751638 @default.
• W2116028075 hasRelatedWork W4229506305 @default.

• next